"Pramistar": reviews of doctors and patients, instructions for use
What is the drug "Pramistar"?Instructions, reviews about this medicine will be described below. Also we will tell you about what properties this medicine possesses, what purposes it is prescribed, whether it has side reactions and contraindications.
Composition, Description, Forms
In what kind of packaging is the "PRIMISTAR" drug sold? Tablets( reviews about this drug are ambiguous) are placed in contour packs that are contained in cardboard packs.
The active substance of the drug is pramiracetam. Also included are auxiliary ingredients in the form of polyethylene glycol, colloidal anhydrous silicon dioxide, crospovidone, calcium stearate, hydroxypropylcellulose, titanium dioxide, polyethylene glycol, microcrystalline cellulose and hypromelose.
The tablets are coated with a coat, they have a white color and an elongated shape with a risk.
Pharmacodynamics of the drug
How does the medicine "Pramistar" work? The doctors' reviews say that the active component of this remedy is for nootropics, pyrrolidine derivatives and racemates. The drug improves memory, activates motivation processes and promotes learning.
The principle of action of this medication has not been studied to the end. However, experts argue that this medication is able to activate high-affinity capture and neuronal activity of choline in the cholinergic parts of the brain.
It should also be noted that the drug in question is actively involved in the synthesis of phosphatidylcholine. It restores the structure of the membranes of neurocytes and improves their plasticity.
How is the effect of the medicine "Pramistar" manifested? Patients' feedback indicates that this remedy does not have a sedative effect, but at the same time it directly affects the central and autonomic nervous systems.
The active substance of the drug increases the time during which people can concentrate on something. Also, the medicine improves memory and activates mental work.
After taking the tablets, the structure of the reticular formation is restored, and the microcirculation of the brain tissues is normalized.
Experts believe that this drug is very effective as an antidepressant.
Pharmacokinetics of oral medication
Is the drug "Pramistar" absorbed? Reviews say that after taking the tablets their active ingredient is quickly and completely absorbed into the bloodstream. The greatest content of prirametcetam in the blood is observed after a lapse of two hours. The half-life period is six hours.
The drug is not metabolized in the liver and does not bind to plasma proteins. It is excreted unchanged with urine.
Indications for the use of a nootropy
What can the "Pramistar" preparation be used for? Reviews say that such a tool is actively used in:
- senile dementia;
- of discirculatory encephalopathy;
- memory corruption;
- emotional lability.
It should also be noted that this medication can be used during recovery after TBI and ischemic stroke, in elderly people to improve thinking and remembering processes, to increase motivation, concentration and interest in life, to eliminate irritability, melancholia and various cognitivedisorders.
Contraindications to the use of
Under what conditions can not prescribe "Pramistar"( tablets)?Instruction, reviews speak about the following contraindications:
- pregnancy and breastfeeding;
- hemorrhage in the brain;
- allergy to drug substances;
- severe liver or kidney disease.
Preparation "Pramistar": instructions for use
You can find feedback on the effectiveness of tablets at the very end of the article.
According to the enclosed instructions, the product should be swallowed whole. To achieve the desired result, the drug should be taken at least a month. Typically, the course of therapy is sixty days.
The drug "Pramistar" is prescribed one tablet twice a day. Correction of dose for elderly patients is not required.
People with kidney disease should be monitored during the course of treatment. If any undesirable effects occur during this process, then the therapy must be stopped.
Cases of overdose with tablets
To date, there have been no reported cases of overdose with the drug in question. If the recommended dose has been exceeded, then you should rinse the stomach, and take enterosorbents.
Side effects of
Does the drug "Pramistar" cause undesirable reactions? Reviews say that the side effects of this tool are extremely rare.
In some cases, the following phenomena are possible:
- dizziness, severe agitation, headaches, tremor;
- indigestion, dryness of the oral mucosa, pain in the abdomen, nausea;
- insomnia, dysphoria, urinary incontinence, confusion;
- anorexia, fecal incontinence, spasms.
Drug Interaction
Before using this medication, always be aware of its drug interaction. According to the instructions, it is not recommended to take it simultaneously with "Captopril", "Digoxin", "Warfarin" and "Theophylline".
The drug "Pramistar" is able to reduce the processes of platelet aggregation. In this regard, it should not be combined with anticoagulants and inhibitors of platelet aggregation.
Such side effects as irritability, insomnia or confusion increase with the simultaneous administration of "thyroxine" and "triiodothyronine", as well as with other thyroid hormones.
Special recommendations
The use of medication in patients with renal insufficiency should be accompanied by strict control of kidney function.
If the patient exhibits such side effects as confusion, tremors and dizziness, then driving is highly discouraged.
Synonyms, prices and analogues of
The synonym for this drug is the preparation "Pramiracetam".There are also a number of analogues that have a similar mechanism of action. They include the following medicines: "Pikamilon", "Aminalon", "Lira", "Biotropic", "Glycine", "Vasavital", "Bifren", "Vicerebrol", "Encephabolus", "Gamalate B6", "Cerebrolysin"," Dendricks "," Fenotropil "," Cavinton "," Phenibut "," Calcium Gopantenate "," Fezam "," Vinpotropil "," Pantogam "," Noben "," Pyracetam "," Thiocetam "," Omaron ", "Cogitum", Noophen, "Noopept", "Nootropil", "Neuro-Norm", "Ceraxon", "Neurovin", "Cognum", "Quattrex".
It is rather problematic to buy this drug on the territory of the Russian Federation. Therefore, most patients order it in online pharmacies. It should be noted that the cost of this medicine is very high and amounts to 1500-2500 rubles.
Pramistar preparation: feedback on the effect of
Despite the fact that it is problematic to buy a nootropic drug in conventional pharmacies, there are quite a few reviews about it. It should be noted that they are ambiguous.
Most patients who have been prescribed this medication report that the medicine "Pramistar" significantly improves and improves memory, stimulates thought processes and stimulates motivation for active activity.
Some people who have completed a full course of treatment claim that after taking the pills they became "completely different".
With regard to negative reviews, they are most often associated with the development of unwanted reactions. Of the side effects, you can especially highlight nausea and drowsiness. By the way, drowsiness is very clearly manifested in the first few weeks of treatment. It should be noted that almost all patients get enough sleep much better. They dream only memorable and vivid dreams.
In addition to improving memory and mental activity, this tool proved effective in the therapy of craniocerebral injuries, as well as in the restoration of cognitive abilities in the elderly.
According to the patient's feedback, this drug significantly improves learning ability. Thanks to him you can pass exams well. Although some young people argue that after a month's course, this drug causes obsessions. In this case, its abrupt reversal leads to drowsiness and lethargy.
Most people who use or want to use this tool are confused by its price. Compared with other drugs of a similar effect, "Pramistar" is very expensive. Moreover, it is difficult to access.
With regard to the feedback of specialists, they report that the drug should be taken only after consultation with the doctor, and also under its strict control. It should also be borne in mind that the medication we are considering is intended only for the treatment of serious disorders in the CNS.It is prohibited to use it at its discretion. Otherwise, it can be detrimental to the patient's health and his psycho-emotional state in general.