"Ftoruracil" preparation: instructions for use, description, composition, analogues and reviews

Oncological diseases, unfortunately, are now very common. Naturally, you can not give up, you need to fight this pathology. In no case should you be treated yourself. You can not do without qualified help. The fact is that some medicines can be prescribed only by prescription and are used only by a special admission scheme. In many cases, doctors prescribe a drug such as "fluorouracil".Instructions for use of this medication will be set out below.

General description of

So, the presented medicine is used in oncology, since it has antitumor effect. It can be classified as anti-metabolites. That is, the substance contained in the liquid, can significantly slow down the metabolism between cells.

"Fluorouracil"( instruction for use always goes in the package with the drug) has a simple composition. It includes water sterilized and caustic soda. The main active ingredient is fluorouracil.

Forms and features of taking the drug

It should be noted that this drug has several forms. If you need "Ftoruracil", the instructions for use tell us about its types:

1. Liquid solution for intravenous or intracavitary injection. Most often this happens 5% aqueous mixture in ampoules of 5 ml. There is also a concentrated solution, which is placed in a 10 ml bottle.

2. Ointment. It is usually also 5%.It is used to treat skin pathologies, for example, basil.

If you were assigned "Fluorouracil", the instructions for use contain such information regarding the reception schemes:

- Every day take 0.5 g / m2.or 12 mg / kg. The course of therapy is no more than 5 days. After this, a one-month break is necessary.

- Once every 7 days 0.6 g / m2.The course of therapy is about 6-10 weeks.

- In combination with other antitumor drugs - on the 1st and 8th day of the course, 0.6 g / m2.

However, in all cases, the dosage and method of taking the drug are individually prescribed. It all depends on the severity and stage of the disease, the general condition of the patient, his state of health, and the plan for chemotherapy.

The liquid can be injected or dripped. It should be borne in mind that some drugs that are given to the patient in conjunction with this, provide a decrease in the dose of fluorouracil by 20-30%.So, "Fluorouracil"( instructions for use, the description of the drug must necessarily be read by the patient) has an anti-inflammatory effect and significantly slows down the chemical reactions that contribute to the division of malignant cells.

. Pharmacological action and interaction with other drugs. That is, the substance blocks the formation of DNA.

The drug is absorbed quickly enough, with the formation of fluorouridine monophosphate. It is split in the liver for about 20 hours. Respiratory organs( 60-80%) and kidneys( 7-10% in unchanged state) are involved in excretion of the drug.

If you need to take "fluorouracil", the instructions for use( the composition of the drug we have already considered) states that there are some substances that can not be combined with it. For example, sulfonamide drugs and phenylbutazone are incompatible with said agent. But alpha-interferon and cytostatics, on the contrary, strengthen the action of "fluorouracil".This should be taken into account when prescribing a dosage.

Please note that the vaccination of the patient, due to its weakened immunity, should be carried out no earlier than 3 months - a year.

Indications for use

If you require "Fluorouracil", instructions for use( the average price of the medication is 3000-3990 rubles) tells about such medical indications:

• Oncological disease of the small or rectum, esophagus and stomach. In this case, the drug is prescribed even with an inoperable stage or the presence of metastases.
• Primary liver cancer.
• Malignant pathologies of the gallbladder, ovaries, breast, cervix.
• Adrenal cancer.
• Oncological lesion of the prostate.
• Carcinosis or cancer of the penis.
• Tumors in the neck and head.
• Pre-cancerous condition, as well as small tumors.

This medication can be used even with fungal skin lesions.

What contraindications exist?

Naturally, no chemical preparation can be equally useful for all patients. And in this case the substance has some contraindications to the application.

• Too high sensitivity to some components of this tool.
• Pregnancy or lactation. This medicine has an extremely toxic effect on the fetus. If the reception is prescribed during breastfeeding, the baby is taken from the chest.
• Peptic ulcer of the duodenum or stomach, which is in the stage of exacerbation.
• Severe anemia and frequent bleeding that is difficult or impossible to stop( hemophilia).
• Leukopenia.
• Disturbance of kidney or liver function.
• Patient's state of health, preceded by biological death.
• Extremely severe depletion.

In addition, there are some limitations. For example, with caution the drug is prescribed to those people who suffer from herpes zoster or chickenpox. Special attention should be given to the purpose of this drug if the patient is already taking cytostatics.

Possible side effects of

If you are prescribed a course of a drug such as Fluorouracil Lance, the instructions for using this medication are practically the same as those written earlier. The issue that interests many patients is the side effects. The fact is that sometimes they can be more complicated than the disease itself. So, after taking the substance, such side effects can be observed:

• Reduction of the number of leukocytes and platelets in the blood.
• Nasal bleeding, which can be difficult to stop.
• Vision disorders, optic neuritis.
• Nausea, which can be associated with vomiting and diarrhea. In this case, treatment should be suspended or changed.
• Stomach ulcer.
• Stomatitis.
• Partial or complete alopecia( alopecia).
• Ischemic heart disease, arrhythmia, angina pectoris, heart failure, myocardial infarction, cardiomyopathy, thrombophlebitis.
• Pain and circling in the head, increased tearing and fear of light, disorientation in space, loss of clarity of consciousness.
• Dysatria.
• Disturbance of taste, gastric bleeding, heartburn, decreased appetite and liver function.
• Shortness of breath, cough, bronchospasm.
• Violations in the reproductive system: in women - no menstruation, in men - azoospermia.
• Hyperpigmentation of the skin, its dryness and cracking.
• Urticaria, skin rash, dermatitis.
• Muscle weakness, as well as attachment of infections of various nature.

As you can see, the presented liquid or "Fluorouracil" ointment, the instructions for use of which are already clear to you, are quite dangerous medicines. In addition, some studies show the possibility of a strong toxicogenic and carcinogenic effect of the drug.

Storage conditions for the product

So, you have already received quite a lot of information about the product presented. Now we need to consider the features of its storage. To be in the "Ftoruracil" should be in a very dark place. The storage temperature should be 15-25 degrees. Naturally, the medicine should be kept away from places accessible to children. Freezing the liquid is highly discouraged.

Shelf life of the drug is 2 years. After this time, the product can not be received.

There are cases when a deposit appears on the bottom of the ampoule. This occurs during long-term storage. Try to warm up the liquid to 60 degrees with vigorous shaking. Then cool the substance to 35 degrees. If the precipitate dissolves and the liquid becomes transparent again, then the preparation is ready for use.

Analogues of the medicine

The main thing that you need to know before taking the drug "Ftoruracil" - instructions for use. The reviews will also be superfluous. You will learn about them later.

If the patient can not purchase this medicine, the doctor can prescribe analogues. They have the same main active substance - fluorouracil. Now there are such analogues of this drug:

1. "Fluoroo-Uracil".

2. "Efundex".

3. "Efu-Rix".

4. "Fluoroplex".

5. "Fluracil".

6. "Fluoril".

7. "Queruplex".

8. "Timazin".

Reviews

It should be noted that this drug is used often enough. Many patients note the high effectiveness of the drug in the fight against tumors.

However, they also talk about a large number of side effects: nausea, vomiting, headache, disorientation in space. This is not surprising, since the drug is extremely toxic.

Thus, we have information about the drug "Ftoruratsil": instructions for use, price, reviews. Remember that you can not take this medicine on your own. Be sure to consult a doctor. Otherwise, you risk harming yourself even more. Moreover, only a narrow specialist can establish a correct diagnosis after appropriate studies. Be healthy!