"Diabeton" or "Maninil" - what is better for the treatment of diabetes?

The number of patients with diabetes mellitus has recently increased significantly. Harmful habits, poor nutrition, lack of quality sleep are all factors that lead to the development of the disease. An important role is played by hereditary predisposition, as well as pancreatic disease. It is this body that is responsible for the production of insulin. With insufficient functioning of the gland develops diabetes. Insidious disease requires quality and competent treatment. In the early stages of the disease widely used drugs such as "Diabeton" or "Maninil."What is better to use? The decision should be taken together with the doctor.

Preparation "Diabeton"

This is a hypoglycemic agent, a second generation sulfanylurea derivative. With the help of beta-cells of the pancreas, the drug helps to produce insulin, increases the sensitivity of peripheral tissues, reduces the time interval from the time of food intake to the beginning of insulin production, normalizes vascular permeability.

The drug has an antigenic effect, reduces the blood levels of total cholesterol. Does not give the medicine to develop microthrombosis and atherosclerosis, it normalizes microcirculation of blood. With the development of diabetic nephropathy, the level of proteinuria decreases against the background of the long-term adoption of glyclosides. Therefore, specialists often designate the means "Maninil" or "Diabeton".What is better to use in a particular case, the doctor decides after conducting a series of tests.

Pharmacokinetics

After ingestion into the stomach, the substance is quickly cleaved. The maximum effect is achieved 4 hours after admission. The connection with plasma proteins is almost 100%.In the liver, the active ingredient forms about 8 metabolites.

Is excreted from the body by the medication for 12 hours in a greater degree by the kidneys. Not more than 1% leaves with urine unchanged. Which is better, "Diabeton" or "Maninil", tablets to take, the endocrinologist will prompt. Experts note that drugs have a similar effect on the body.

Indications and contraindications

The preparation "Diabeton" is indicated in case of diabetes of the second type, which is not insulin-dependent. Also, the medicine is prescribed as a prophylaxis for the disturbance of microcirculation in combination with other agents.

Contraindications to the use of tablets are type 1 diabetes, coma or pre-coma. You can not prescribe a medicine for ketoacidosis, impaired kidneys and liver. It is not recommended to combine glyclosides and imidazole derivatives. With increased sensitivity to sulfonamides and sulfonylureas, tablets "Diabeton" or "Maninil" are not used. The reviews show that misuse of drugs can lead to the development of side effects.

Dosage of

Initiate therapy with a dosage of 80 mg. Daily allowance can not exceed 320 mg. The drug is taken twice a day after meals. The course of treatment can be quite long. The decision to discontinue therapy is taken by the doctor after a thorough examination of the patient.

In hospital conditions tablets "Diabeton" or "Maninil" can be used. What is better to take in a particular case? Preparations are analogues. There is no significant difference between the two. Choose a tool is desirable after consultation of the endocrinologist.

Side effects of

When using the drug, such unpleasant symptoms as vomiting, nausea, and stomach pain can be observed. In rare cases, may develop leukopenia or thrombocytopenia. Some patients experience an allergic reaction. It manifests itself in the form of a rash and itching. In case of an overdose, the drug may be hypoglycemia.

During the period of therapy it is necessary to regularly make a blood test for glucose. It is not recommended to take the medication together with medications containing verapamil and cimetidine. Funds "Diabeton" and "Maninil" reviews of doctors are mostly positive. If these drugs are used in accordance with the instructions, they help to significantly improve the health of patients with diabetes.

Tablets "Maninil"

This is a hypoglycemic agent for oral administration. The main substance in the composition of the drug is glibenclamide. It is manufactured in the form of tablets with different dosages. The medicine is dispensed in a plastic container. Each package contains 120 tablets.

If the specialist proposes to purchase the "Maninil" or "Diabeton", what is better to use? The drugs have a similar effect. The decision should be taken after studying the instructions for the use of drugs.

Action of "Maninil"

The drug belongs to the group of sulfanylurea derivatives of the 2nd generation. Has an hypoglycemic effect on the body. Helps betakletkam pancreas to produce insulin. Insulin begins to be produced immediately after a meal. The hypoglycemic effect persists throughout the day.

So what to choose - tablets "Diabeton" or "Maninil"?Which drug is best for alleviating the condition of the patient? The decision will help to take the doctor after a series of tests.

Indications and contraindications

The indication for the use of the drug "Maninil" is considered type 2 diabetes. It is taken individually or in combination with other hypoglycemic drugs. Do not administer the product with increased sensitivity to the components of the tablets.

Contraindicated in the treatment of diabetes mellitus of the first type. It is not recommended to use the remedy after surgery on the pancreas. Severe leakage of renal or hepatic insufficiency is also a reason for prohibiting the use of Diabeton or Maninil tablets. That it is better to accept, if there are contraindications, the expert will prompt. Self-medication is not worth it.

Dosage of

The dosage of the drug depends on the severity of the disease, as well as the glucose in the patient's blood. At the initial stage, no more than two tablets per day should be taken. To avoid the development of hypoglycemia, elderly patients are prescribed a medicine in a reduced dosage.

Have a similar effect on the body preparations "Diabeton" and "Maninil."Comparison makes it clear that drugs can be used for the same symptoms. Contraindications and side effects also do not differ.

"Diabeton" or "Maninil" - what is better?

What means to choose for the treatment of diabetes, should the endocrinologist decide individually. Be sure to take into account the individual characteristics of the body.

It should be remembered that the medicines differ in composition. Particular attention to the choice of a drug should be given to people who are prone to allergic reactions.