Rexetin: instructions for use
The drug "Rexetin" refers to antidepressants.
Pharmacological properties of the drug "Rexetin" instructions for use describes this: the active substance of this drug - paroxetine is a complex bicyclic compound with both antidepressant and anxiolytic effects on the human body. This means that against the background of the main pharmacological effect, the drug has a pronounced stimulating effect on the central nervous system. The use of the drug causes a reduction in the obsessive-compulsive disorder. The anxiolytic and antidepressant effects of the drug are due to its ability to cause an increase in the amount of free serotonin in the synaptic clefts, due to a decrease in the capture of the presynaptic membrane of the neurotransmitter, from which the effects that arise when the serotonergic system is activated are significantly enhanced. In addition, the drug is characterized by a timoanaleptic effect. Rexetin is well absorbed from the GCS, and food intake has no effect on its absorption. Paroxetine binds very well to proteins contained in the blood plasma. Metabolized he cells of the liver, while metabolites are formed, which are pharmacologically inactive and are excreted mostly by the kidneys. The average half-life is between fifteen and twenty-four hours. In case of prolonged use, the drug is not characterized by cumulation.
Indications for the appointment of the drug "Rexetin" instructions for use calls such:
1) various kinds of depression, including those that are accompanied by a sense of anxiety;
2) treatment of obsessive-compulsive disorders, as well as the prevention of their recurrence;
3) neuropsychic disorders accompanied by panic attacks and agoraphobia;
4) post-traumatic mental disorders that are associated with stress caused by a catastrophe or a life-threatening condition;
5) syndrome of social phobia.
The method of application of the drug "Reksetin" instructions for use gives this: take it together with food intake, do not chew the tablet, and swallow whole, washing down with water. The daily dose is taken at one time, preferably in the morning. With depression and social phobia, treatment usually lasts two to three weeks with a dose of twenty milligrams. With insufficient effectiveness, it is increased by ten milligrams every two to four weeks until the necessary therapeutic effect is achieved( but not more than fifty grams per day).
In the case of the treatment of obsessive-compulsive disorders and panic conditions, the daily dose is twenty milligrams, usually for two to three weeks, if necessary, increase it by ten milligrams, every two four weeks( but a dose of sixty milligrams a day does not exceedrecommended).
Side effects from the use of the drug "Rexetin" instructions for use leads to such: dizziness, headache, sleep disturbance, limb tremor, paresthesia, fatigue, irritability, convulsions, excessive sweating, visual impairment, heart rhythm, hypotension and hypertension, fainting, nausea, vomiting, decreased appetite, impaired liver function, decreased libido, ejaculatory dysfunction, difficulty urinating, skin flushing, bruising, itching of the skin, bronchospasm, Quincke's edema, hyponatriumI, myopathy, myalgia, and so on. At the beginning of therapy, these manifestations are more pronounced, and then gradually decrease.
Contraindications: individual intolerance to the components of the drug, age to 18 years, use of tryptophan and MAO inhibitors, pregnancy and lactation. Interaction with other medicines: can not be used with MAO inhibitors and within two weeks after their withdrawal, tryptophan, ethanol, anticoagulants;with sumatriptan only under medical supervision and so on.
And what are the analogues of Rexetin?
These are the preparations: "Paroxetine", Cyprus;"Paroxin", Ukraine;"Xset", India;"Luxoft" and "Cloxel".
Does the withdrawal syndrome develop when discontinuing the drug "Rexetin"?
No, the fact that people can be mistaken for withdrawal syndrome, in fact, are manifestations of an untreated disease.