The drug "Khondra-Sila": the instruction, analogues and reviews of doctors
Many patients suffering from diseases of the musculoskeletal system know firsthand what constitutes the drug "Khondra-Sila".Tablets and ointment, produced under this name, can be purchased at any pharmacy.
In this article, we will tell you how to use the agent in question, in which cases it is prescribed most often, that patients are informed about it.
Composition, form, packaging
This medication can be purchased at a pharmacy in such forms as:
- Oral preparation "Chondra-Sila"( capsules).The active ingredients of this form are: chondroitin sulfate and glucosamine hydrochloride. Also, the composition of the medicinal product includes auxiliary components.
- The drug for external use "Chondra-Sila"( ointment).The active substance of this form is chondroitin sodium sulfate. In addition, this composition includes additional elements in the form of dimethylsulfoxide, white soft paraffin, lanolin and purified water.
The drug "Khondra-Sila", the price of which is listed below, is on sale in cardboard packs. The ointment is contained in polyethylene tubes, and the capsules are contained in the cell packs. Also, they are accompanied by detailed instructions for use.
Pharmacological characteristics of
What determines the effectiveness of the drug "Chondra-Sila"?The instruction says that by its curative effect this medicine is obliged to the substances that make up its composition.
Chondroitin is a high molecular weight mucopolysaccharide, which is found in large numbers in completely different types of connective tissue( including cartilaginous).It is an additional substrate for the formation of a cartilaginous matrix.
The element under consideration inhibits the resorption of bone tissue and reduces the loss of calcium. It also affects the phosphorus-calcium metabolism that occurs in the cartilaginous and bone tissues, accelerates the processes of their recovery, slows down degeneration, stimulates regeneration and promotes the restoration of articular bags and joint surfaces.
It should also be noted that chondroitin maintains the density of synovial fluid, plays an important role in the lubrication of articular surfaces and prevents the compression of connective tissue. It also inhibits the progression of osteoarthritis, reduces a person's need for NSAIDs, reduces the severity of pain, normalizes metabolism in hyaline tissues, stimulates the synthesis of proteoglycans, the formation of hyaluron and collagen of the second type.
Chondroitin in the composition under consideration is able to protect hyaluron from enzymatic cleavage( eg, lysosomal enzymes), which is the main cause of destruction of connective tissues.
Properties of glucosamine
What other properties are inherent in the oral agent "Chondra-Sila"?Capsules, in addition to chondroitin, contain an ingredient such as glucosamine. This is an endogenous substance that is part of glycosaminoglycans and proteoglycans. It is able to activate the synthesis of proteoglycans, chondroitinsern and hyaluronic acids, as well as other elements that are a building material for intraarticular fluid, articular membranes and cartilaginous tissue.
The presented element enhances the synthesis of the cartilaginous matrix and normalizes the processes of calcium deposition in bone tissue. It also protects cartilage from chemical damage, including those caused by the intake of glucocorticoids and NSAIDs.
Glucosamine is able to have a moderate anti-inflammatory effect. Its regular reception inhibits degenerative processes in joints, near-vertebral soft tissues and spine.
Due to this element the considered preparation participates in biological synthesis of connective tissue, stimulates the regeneration of cartilage and prevents the processes of their destruction.
Thus, the drug "Khondra-Sila", the instruction of which is presented below, has regenerative, anti-inflammatory and analgesic properties. Its use improves the mobility of joints and reduces the patient's need for NSAIDs, which significantly improves his quality of life.
When does the drug "Chondra-Sila" start? The instruction informs, that steady medical effect is observed at use of a medicament during half a year.
For oral administration of capsules, a 90% dose is absorbed from the digestive tract. The greatest concentration of the drug in the blood is noted in an hour. The bioavailability of the drug is 13% for chondroitin and 25% for glucosamine.
After distribution, the drug is found in the kidneys, liver and articular cartilage. It is excreted in urine and feces.
What kinetic parameters does the external tool "Chondra-Sila"( ointment) have? The pharmacokinetics of this form of the drug has not been investigated.
Capsules and ointment "Khondra-Sila", reviews of which are positive, are prescribed for the complex treatment of diseases of the musculoskeletal system, as well as other conditions that are accompanied by degenerative and dystrophic changes in the tissues of the articular cartilage. These include:
- secondary and primary osteoarthritis, periodontopathy and osteoporosis;
- osteochondrosis, humeropathy periarthritis, patellar chondromalacia, spondylosis.
This medication is not prescribed if hypersensitivity to any of its substances, phenylketonuria, a tendency to bleeding, severe kidney disorders, acute inflammatory processes at the site of application and thrombophlebitis. Also, it is not used in breastfeeding, at the age of 12 years and during pregnancy.
Preparation "Khondra-Sila": instruction
Capsules "Khondra-Sila" are prescribed only inwards. Adults and adolescents at the beginning of treatment are advised to take 2 capsules twice or four times a day. After 30 days, the dosage can be reduced to 2 capsules once or twice a day.
The clinical effect of taking such a drug is slow. However, it can persist for a long time after the termination of the course of therapy.
The minimum duration of treatment for this drug is 6 weeks, and the maximum - 2-3 months.
As for the external form of the drug, it should be used three times a day. The ointment is applied to the affected area with a thin layer and is easily rubbed to a full suction.
The duration of this course is determined on an individual basis, depending on the tolerability and effectiveness of therapy( usually 2-3 weeks).If required, the course can be repeated.
The drug "Khondra-Sila": the price and analogues of
You can buy this medication in any pharmacy. Its cost varies between 180-450 rubles( depends on the form of release, the volume of the tube and the number of capsules in the package).
If this drug is contraindicated to you, then it can be replaced by one of the following means. They include: Diclofenac, Voltaren, Indomethacin, Remisid, Nemid, Ketonal, Hondrolon, and so on.
Reviews about the medicine
Both the ointment "Khondra-Sila" and the capsules are equally good at the task. These funds effectively treat diseases of the musculoskeletal system, and also stop the degenerative and dystrophic changes taking place in the tissues of the articular cartilage.
Patients and doctors claim that the medicine in question permanently removes the pain associated with such diseases as humeropathy periarthritis, osteochondrosis, patellar chondromalacia and spondylosis. In this case, he practically has no contraindications and side effects.