Medication "Indapamide": from what saves and how to take

Medication "Indapamide" affects the vascular walls, relaxing them and normalizing the elasticity of the muscles. Due to this drug increases arterioles, which leads to unhindered movement of blood in the body. Tablets "Indapamide" - a cure for pressure. It is a vasodilator, according to pharmacodynamics similar to a thiazide diuretic. During the day the amount of urine produced increases slightly. Together with it, the predominant sodium ions, chlorine, and potassium are removed from the body. During the intake of the drug carbohydrate and fat metabolism remain normal, which makes it possible for the patient to take the drug with obesity or diabetes. With a marked increase in the left ventricle of the heart, the medication "Indapamide" significantly reduces the level of hypertrophy. With regular use of the drug, the effect is achieved after 2 weeks, and after 10 weeks, the maximum beneficial effect is observed. A single dose of medication "Indapamide" retains the therapeutic property up to 24 hours.

Pharmacokinetics

The drug "Indapamide" is rapidly absorbed in the gastrointestinal tract and is excreted from the body mainly with urine. The content of inactive metabolites in feces is about 20%.Diuretic interacts with plasma and erythrocytes, penetrates into breast milk. With regular use of the drug, cumulation is not noted. Patients with hepatic insufficiency should be cautious about using this medication to avoid the formation of liver encephalopathy.

Indications for use

Why does the medication "Indapamide" help? Indications for its use are:

• Arterial hypertension.
• Chronic heart failure( sodium and water retention in the body).

Contraindications

Administration of the drug is limited in the following diseases:

• Violation of the functions of the liver.
• Impaired renal function.
• Intolerance to the components of the drug.
• Hypokalemia.
• Disturbance of blood circulation in the brain and spinal cord system.
• Gout.

In what cases can complications occur when using the medication "Indapamide"

What is recommended to take this drug, we have already found. But when you need to take extra care when using it? Such cases include:

• Lactose intolerance.
• Pregnancy and lactation.
• Age under 18 years old.
• Unstable water-electrolyte balance.

Method of administration, dosage

The drug is taken orally once a day for 2.5 mg. Morning reception is more effective, because a large amount of food slows the assimilation of the medicine. Tablets should be swallowed, not liquid, squeezed with enough water. Increasing the dose of the medication "Indapamide" does not lead to acceleration of the therapeutic effect, but causes a number of side effects. Patients suffering from heart failure, with no improvement, are prescribed a dose of 5 mg per day.

ADVERSE REACTIONS

When taking the drug "Indapamide"( from which it is prescribed, we already know) there may be a side effect. First of all, this happens with the use of an increased dose of medicine, intolerance of the substance by the organism, the effect of individual components on a certain system of organs. Side effects can manifest themselves in different ways.

• Central nervous system: headache, drowsiness, asthenia, insomnia, irritability.
• Respiratory system: pharyngitis, acute cough.
• Digestive system: nausea, vomiting, diarrhea.
• Urinary system: nocturia, infectious inflammation.
• Cardiovascular system: arrhythmia, heart palpitations, hypokalemia.
• Skin diseases: itching, urticaria, rash.

Price

The average price of the drug "Indapamide" in Russia - 12 rubles. The package contains 30 tablets of 2.5 mg each.

Interaction with other drugs

Anti-inflammatory drugs reduce the effect of medication "Indapamide", quickly expend liquid in the body, because of what it has to constantly replenish. When taking the tablets "Indapamide" on what does compatibility with other drugs depend? The composition of the diuretic is rather complicated, therefore complex treatment is selected by a specialist strictly individually, proceeding from the prescribed medications.

• Drugs with lithium content are rapidly excreted in the urine, so it is necessary to monitor the level of the substance in the blood serum.
• GCS, on the contrary, detain water in the body, reducing the antihypertensive effect.
• Cardiac glycosides reduce the amount of potassium in the body, which can lead to hypokalemia.
• Calcium: an increase in the salt content in the body.
• Radiopaque preparations containing a significant amount of iodine can lead to the development of renal failure.
• Tricyclic antidepressants cause the risk of orthostatic hypotension.

Special instructions

Which patients need close monitoring of the condition when taking the drug "Indapamide"?From what they need to be protected? Patients with cirrhosis of the liver, heart, kidney, liver failure are required to undergo treatment with the drug "Indapamide" strictly under the supervision of doctors. The possible appearance of dehydration in the body leads to an aggravation of the organ functions. It is important to control the fluid content in the body and compensate it in time.