"Domrid": instructions for use, reviews and analogues

Recently, in almost all countries there has been an increase in the number of gastrointestinal diseases. One of the most common pathologies is a syndrome of functional dyspepsia, or a digestive disorder. This problem has a very negative impact on the quality of life. Such a pathology is most often diagnosed in young people. To get rid of such a negative symptomatology doctors prescribe the medicine "Domrid".The drug's instruction indicates that this product effectively removes negative manifestations of gastrointestinal diseases. Let's consider in more detail, at what illnesses it is expedient to accept a preparation, in what dosages, to whom the given medicine is counter-indicative.

Brief description of

The preparation "Domrid" instruction is positioned as a propulsant, or stimulant of peristalsis. In people, the medicine is better known as an excellent antiemetic. The active substance of the drug is a dopamine antagonist. It has antiemetic properties of peripheral and central action.

Drugs "Domrid" instruction states that the drug provides several functions in the human body:

• increases the duration of antral and duodenal contractions;
• improves the movement of food through the digestive tract;
• stimulates the release of solid, semi-solid, liquid fractions from the stomach;
• improves the production of the pituitary gland prolactin.

The active substance of the drug through the blood-brain barrier practically does not penetrate. The use of the drug does not affect the secretory activity of the glands of the digestive tract.

After the use of the drug, it quickly enters the systemic circulation. The highest concentration of the drug is found in the blood 30-60 minutes after administration.

Forms of release

For the convenience of patients, the medicine is produced in several forms:

• tablets;
• suspension;
• tablets prolonged action.

Indications for use

The drug "Domrid" is intended for the treatment of patients who have a complex of dyspeptic symptoms.

It can manifest:

• by delayed stomach emptying;
• by esophagitis;
• is heartburn, in which food is thrown into the esophagus;
• sensation of overcrowding of the stomach;
• pain syndrome in the epigastric zone;
• gastroesophageal reflux without heartburn;
• with vomiting, nausea;
• flatulence.

The drug may be administered to patients in certain other pathologies. If a person has nausea, vomiting of an unexplained nature, then the doctor will recommend to take this medication. Excellent fight with unpleasant symptoms of the drug "Domrid" with poisoning. Often such pills are advised for people who have nausea provoked by chemotherapy or radiation therapy.

In addition, the medicine perfectly eliminates the negative symptoms provoked by certain medications. So, for example, tablets "Domrid" are able to cope with nausea, vomiting caused by taking drugs "Levodopa", "Bromricrytin."

The medicine and children are also effective enough. For children the special form of preparation "Domrid" - suspension is intended. The instruction recommends the use of medication to reduce the severity of such negative symptoms as vomiting, nausea.

Dosage tablets

Medication "Domrid" should be taken as prescribed by the treating doctor. He will describe in detail the scheme of using this remedy.

According to the instructions given, the "Domrid" tablets are taken according to the following rules:

1. The drug is intended for oral use.
2. To achieve maximum effect, pills are recommended to take 15-20 minutes before meals.
3. Do not grind or chew the tablet.
4. The duration of therapy depends on the clinical picture of the pathology and is determined by the physician.
5. For chronic dyspepsia, adults are prescribed 10 mg 3 times a day.
6. If necessary, you are allowed to take a fourth dose( 10 mg) before bed.
7. If the patient is diagnosed with a severe form of ailment, then the above dose is doubled.
8. When nausea, vomiting, the patient is prescribed to take the medicine three times a day for 20 mg. An additional dose( overnight) is also allowed, if necessary.
9. The daily maximum allowable medication is 2.4 mg / kg. However, it should not exceed 80 mg.

Application of tablets "Domridum SR"

This is a prolonged-release preparation. The treatment scheme is also prescribed by the doctor.

The instruction gives the following recommendations for the reception of such tablets:

1. For acute conditions( nausea, vomiting) or dyspepsia, adult patients should take 1 pill per day.
2. Use medication approximately 15-30 minutes before taking food. The pill should not be crushed.
3. If necessary, you can also use 1 tablet at night.
4. For acute conditions, the duration of therapy is 2 days.
5. For chronic pathologies( dyspepsia), the course of treatment lasts about 2 weeks.
6. The daily maximum dose should not be more than 60 mg.

Use of

suspension It is allowed to use the drug "Domrid" for children. For them, as mentioned above, a special form of this drug is produced - a suspension. However, parents should understand that the medicine can not be used alone. Such a drug must necessarily be prescribed to the child by a doctor. And only the doctor can recommend in what quantity to use a medicine "Domrid" -syrup.

The duration of treatment is completely dependent on the pathology. It is also determined by a pediatrician.

The medication "Domrid"( suspension) instruction is recommended for use as follows:

1. The syrup is taken orally in undiluted state.
2. In order to maximize the effect of the treatment, the suspension should be consumed 15-30 minutes before meals.
3. The set contains a measuring spoon. Use it to accurately measure the required amount of medicine. In the event that it became necessary to collect a dose of less than 2.5 ml, it is recommended to use a disposable syringe( only without a needle).
4. If syrup is taken by adults or adolescents with a body weight of more than 33 kg, it is recommended to drink 10-20 ml of the drug 3 times a day. Can be used an additional portion at night. For this category of patients, the maximum dose within a day should not be more than 80 mg.
5. Children older than 1 year, the suspension is prescribed taking into account the weight. The ratio is as follows: 0.25-0.5 ml per 1 kg. The medication is taken 3 times a day. An additional dose is also allowed, if necessary.
6. Infants under 1 year of age are recommended to calculate the rate based on the ratio of 0.25 ml per 1 kg. The drug is used three times a day. You can give babies at night an extra dose.
7. It should be noted that for children whose weight does not reach 33 kg, the daily allowance, the maximum allowable, is 2.4 ml per 1 kg.

The primary course of treatment should not exceed 28 days.

ADVERSE REACTIONS

The use of this medication can sometimes provoke quite negative symptoms in the patient.

Medication "Domrid" instruction indicates the following possible reactions:

1. Immune system. Such phenomena are extremely rare. Some patients during the therapy may develop: anaphylactic reactions, edema of the face, shins, hands, feet, urticaria, angioedema, allergies.
2. Endocrine system. There may be an increase in the blood of prolactin. This effect is not observed often.
3. Nervous system. During therapy with this medication, patients often complain of headaches, dry mouth. Significantly fewer patients experience such unpleasant symptoms as insomnia, dizziness, lethargy, thirst, increased excitability, irritability, extrapyramidal disorders, drowsiness, convulsions.
4. Heart and blood vessels. In some cases, the following negative effects can occur: puffiness, increased heart rate, lengthening of the QT interval, abnormal heart rate and rhythm, ventricular arrhythmia. With such pathologies, patients rarely encounter.
5. The digestive tract. Rarely, negative consequences can occur in this system. As a rule, patients complain of gastrointestinal disorders, abdominal pain syndrome, regurgitation, diarrhea, changes in appetite, constipation, nausea, heartburn, and short intestinal cramps.
6. Skin covers for .There are cases when patients sometimes have a rash, itch.
7. Mammary glands and reproductive system. There may be such unpleasant disorders as galactorrhea, amenorrhea, gynecomastia. Such manifestations are quite rare.
8. Urinary system. These organs suffer from therapy infrequently. The patient may experience dysuria, frequent urination.
9. Musculoskeletal system. Sometimes patients complain of pain in the legs, asthenia.

In addition to the above side effects, in some cases, there was the occurrence of stomatitis, conjunctivitis.

General contraindications

The drug has limitations to admission. Therefore, it is recommended to consult a doctor first. This will eliminate the risk of serious enough consequences of taking "Domrid" tablets.

The instruction indicates the following conditions in which the drug is contraindicated:

1. Absorption of glucose-galactose absorption, lactase deficiency, galactosemia.
2. Intestinal obstruction, active form of gastrointestinal bleeding, intestinal perforation.
3. Prolactinoma.
4. Dysfunction of the liver, kidneys.
5. Use of preparations "Ketoconazole", "Erythromycin" and other inhibitors of CYP3 A4.
6. The use of drugs that promote the prolongation of the QT interval. These are the medicines Fluconazole, Voriconazole, Amiodarone, Telithromycin, Clarithromycin.

Do not use the tablet form of medication for children who are under 12 years old. Special attention is required for newborns and premature babies. For such crumbs, the suspension is prescribed with increased caution.

People who suffer from diabetes should take into account that sucrose is present in the syrup.

The drug is not recommended for use in pregnant women, because the potential risk is unknown. But in some cases, such a tool is still assigned to future mothers. However, the doctor before such a recommendation necessarily weighs all the risks.

The active substance easily penetrates into breast milk. Whether it causes damage to the crumb is unknown. Therefore, it is recommended to stop feeding the baby during therapy with this medication.

Drug overdose

When carrying out therapy with this drug, it is very important to adhere to the prescribed treatment regimen. It is strictly forbidden to increase the dose independently. Excessive abuse of medication, and in any dosage form, can cause a number of negative symptoms.

The main signs of overdose are the following:

• drowsiness;
• sensation of weakness;
• impaired consciousness;
• disorientation;
• extrapyramidal disorders;
• convulsions.

In this condition, the patient must immediately be assisted. Specific antidote is not developed. Therefore, with the symptoms of overdose, it is recommended to wash the patient's stomach. The patient should definitely drink a sorbent. For example, activated carbon.

Such conditions are often the reason for hospitalization of the patient. In the hospital, doctors monitor the patient's state of health. If necessary, various supporting measures are taken.

Medications for the therapy of parkinsonism, anticholinergics can be used to correct extrapyramidal disorders.

Analogues of medicament

Because gastrointestinal pathologies are quite common ailments, pharmacologists have developed a large number of medicines to combat unpleasant and painful symptoms. Synonyms for this drug:

• "Domperidone".
• "Motilak".
• "Motilium".

If necessary, the doctor will recommend to the patient medication "Domrid" analogues, having the same effect on the body as the original remedy.

These medications are:

• "Domstal".
• Motorcycle.
• "Dimetkarb".
• "Dimetramid".
• Dixaphen.

The cost of the drug

This medicine is produced in Ukraine. At home, the medication "Domrid" is quite inexpensive. The price of the drug depends on the dosage form and packaging.

On average, the cost of medication is as follows:

1. The drug "Domrid", 30 units( 10 mg) - 171 rubles.
2. Tablets "Domrid SR", 30 pieces( 30 mg) - 297 rubles.
3. Suspension "Domrid", 100 ml( 1 mg / ml) - 160 rubles.

Thus, despite the high effectiveness of the drug "Domrid", the price of this remedy is quite acceptable for the masses.

Reviews about

What do doctors and patients think about this drug? Initially, it should be noted that in 2013 the drug was tested for safety, efficacy and tolerability. This event was attended by 25 people who had functional dyspepsia confirmed, and 25 patients diagnosed with gastroesophageal reflux disease. After 2 weeks of therapy, these people had significant improvements. They have decreased dyspeptic manifestations. The parameters of the motor-evacuation functioning of the stomach improved.

Thus, the effectiveness of the drug "Domrid" was fully confirmed. The patient's feedback does not give us the opportunity to question the beneficial effects of the drug on the body. People who are confronted with a rather unpleasant symptomatology - nausea, vomiting, - testify that the drug is able to relieve even the strongest seizures.

Parents who use this medicine for children, argue that painful vomiting and nausea were literally a day. This allowed to stabilize the child's condition. In this case, small patients drink with pleasure this suspension. It has a pleasant pink color and a sweetish strawberry taste. However, after taking a little bitter aftertaste.

But there is another opinion. Some patients consider the drug ineffective. They claim that they drank the medicine for several days according to the scheme prescribed by the doctor. When the unpleasant symptomatology disappeared, they stopped using it, so as not to "stuff" the body with chemistry. As a result, the nausea returned again.

There are also such patients who directly state that taking this medication only worsened the condition. After using the medication, vomiting increased. I had to give up this money.

Summary

Analyzing such diverse opinions, one can conclude one - this tool should be prescribed by a doctor. Take the medicine should be strictly according to the scheme prescribed by the doctor. In addition, one can not exclude individual sensitivity to the drug.