Sodium thiosulfate in psoriasis: particularities of use, efficacy and feedback
There are many poorly studied diseases. Scientists, conducting research, can not always accurately determine the cause of their occurrence. One such is psoriasis. Red inflamed skin, covered with peeling crust during the period of exacerbation, give their carriers a terrible discomfort.
The drug that cures psoriasis does not exist. Scientists have developed a special program, which includes a diet, a set of bath procedures and the use of anti-inflammatory drugs. One of the drugs used in psoriasis is sodium thiosulfate.
Sodium thiosulfate is a salt that exerts detoxification action. It is most often used in case of poisoning with salts of heavy metals( mercury, lead and others).
When poisoning with heavy metals and cyanides, it forms compounds that are less dangerous to humans, which are eliminated from the body through the kidneys.
In medical practice, sterile solutions of sodium thiosulfate 30% and 60% are used. A smaller dosage is used intravenously and orally.60% solution is used only for external application in complex therapy for scabies and psoriasis.
Psoriasis is a poorly understood disease. The reasons for its occurrence are not known exactly, and the methods of treatment can be different. This is due to the specificity and individual course of the disease in each patient.
One hypothesis suggests that the cause of psoriasis is the abnormal behavior of cells responsible for the body's immunity. Psoriatic plaque - a site of inflammation, formed by the proliferation of tissues by excessive division of cells( leukocytes, macrophages and keratinocytes).
The second hypothesis is that the cause of psoriasis can be a number of factors simultaneously affecting the body: severe stress, taking certain drugs, dry, irritable, scaly skin, dermatitis complicated by a fungus or bacterial infection.
If the first reason requires specific treatment, then the second - eliminating the provoking factor. That's when complex therapy comes into effect, which includes several stages.
Psoriasis is a chronic disease with periods of exacerbation and remission. In each case, it is impossible to predict when the acute phase begins. There are sluggish forms, which almost do not affect the quality of life of their carriers.
In the early stages of psoriasis, the attending physician tries as little as possible to harm the patient. For the treatment of mild forms, topical preparations are used: ointments, lotions, creams.
This "easy" treatment is due to the fact that drugs that are prescribed for severe forms of the disease are toxic. They give a lot of side effects and are considered an extreme measure.
If a dermatologist treats psoriasis as a kind of dermatitis, treatment is assigned accordingly. Drugs will be used to purify the liver, as well as ointments that remove redness and flaking.
If we consider that sodium thiosulfate in psoriasis is used precisely as a detoxification agent, there are only two ways of using it: intravenous administration and oral administration. Both methods have their own peculiarities.
How to drink it?
Dermatologists offer two methods of treatment: pierce sodium thiosulfate intravenously or drink for ten days.
The most simple and painless is considered to be taking 30% solution orally. How to drink sodium thiosulfate in psoriasis? It is very simple: a sodium thiosulphate ampoule is diluted in a glass of clean water at room temperature.
The resulting solution is divided into two steps. Half a glass in the morning half an hour before a meal and as much in the evening with a meal or two hours after it. The course of treatment is ten days. At this time it is desirable to adhere to a diet.
On your table should be vegetables, fish or chicken, cereals, soups. Products preferably boiled or steamed. Viscous cereal is in the morning. Exclude potatoes, pasta and smoked products.
With choleretic and laxative action, sodium thiosulfate with mild masses removes toxins and toxins. It is worth paying close attention to the planning of long trips during treatment, especially in the first 2-3 days.
To stab or not to prick?
If the patient has a more neglected form of psoriasis, the attending physician may prescribe a ten-day course of injections. This procedure is carried out daily in a medical institution and only by specialists.
Experienced nurses working in the hospital know that sodium thiosulfate in psoriasis is intravenously injected slowly. The procedure takes from five to seven minutes. If you enter the solution quickly, there may be negative consequences in the form of dizziness, nausea and severe headaches.
After taking sodium thiosulfate, it is necessary to lie down for 10-15 minutes. Thus it is possible to avoid unpleasant sensations.
Sodium thiosulfate may give an allergic reaction in people who are hypersensitive to this drug. In addition, it is necessary to take into account the health of the kidneys. If a person has chronic diseases of this organ, it is worth not to take sodium thiosulfate with psoriasis intravenously or orally. After all, the main way to remove the drug from the body is with urine through the kidneys.
With caution, prescribe this drug to hypertensive people, people with chronic liver diseases, heart failure, as possible worsening of the general condition of patients.
If your doctor has given you a course of sodium thiosulfate in psoriasis, instructions for use should be clearly written by him to avoid an overdose.
Pregnant and lactating
A special issue is the use of sodium thiosulfate in psoriasis in pregnant, lactating women. Clinical studies in this category of patients have not been conducted. Therefore, the application is possible only if the benefit to the mother exceeds the risk to the fetus or there is a need for life indications. Therefore, this category of patients is practically not prescribed sodium thiosulfate for psoriasis.
To have a beautiful tanned skin is the dream of any girl, but it happens that suddenly there are small red spots that increase in size with time, as the disease can progress.
The opinions of the patients who underwent the course of this drug were divided. Most of it gives positive feedback on such a drug as sodium thiosulfate. In psoriasis, only it is recommended and only intravenously.
The only drawback of this procedure is the mandatory presence of a good nurse who can correctly make an injection. After the "bad" introduction, many felt dizzy, nauseated, and abdominal pain.
But this method of reception gives a quick result, noticeable already on the third or fourth day. Redness disappears, the skin becomes smooth and clean.
Those who used the solution for oral administration noted not only the good tolerability of sodium thiosulfate. An additional advantage was the rapid weight loss due to cleansing of the intestine. On average, patients lost from three to five kilograms.
Negative feedback A 30% solution of sodium thiosulfate was obtained in patients with more severe forms of psoriasis. They underwent a course of intravenous injections, but there was no noticeable improvement.
Complicated case of
In case of a complicated fungal or bacterial infection of psoriasis, Demjanovich's solution No. 1, which includes 60% sodium thiosulfate, is used. This drug treats not only various dermatitis complicated by fungi and infections, but also scabies, as well as demodicosis.
According to the instructions, in psoriasis, 60% sodium thiosulfate is used together with hydrochloric acid, which helps to cleanse the upper layer of the skin from dead cells and form a new, healthy one.
When treating with Demjanovich's solution, it is necessary to apply a solution of sodium thiosulfate three to four times a day. It helps to relieve inflammation, itching, unpleasant sensations in the region of formed plaques. And only once affected areas are treated with hydrochloric acid. Thus, the skin is not so badly injured and irritated.
It is impossible to say that the use of sodium thiosulfate in psoriasis is a panacea for a poorly treatable disease. To complete a full ten-day course of therapy, it is necessary to consult a specialist. Only he can say with certainty whether you need to apply it or not. After all, sodium thiosulfate should be introduced with caution: when deviating from the rules, undesirable consequences are possible.