Magnesium Orotas: indications, instructions, analogues, reviews

How can I replace such a drug as "Magnesium Orotate"?Analogs of this tool are listed below. Also in the materials of the article are data on the price of the mentioned medicament, its properties and methods of application.

Form, description, composition

The preparation "Orotat Magnesium" is manufactured in the form of white tablets, round and flat, and also with a risk on one side and with chamfers on both sides.

What is in the composition of this medication? Magnesium orotate dihydrate is its main substance. In addition, the preparation in question includes auxiliary ingredients in the form of carmellose sodium, colloidal colloidal silica, microcrystalline cellulose, corn starch, povidone K30, cyclamate sodium, lactose monohydrate, talc and magnesium stearate.

This product is available for sale in blisters packaged in cardboard packs.

Pharmacology

What is the "Magnesium Orotate" tool? The instruction says that this is a preparation of magnesium. As is known, this substance is the most important macroelement. It is extremely necessary for the human body to provide many energy processes that take part in the metabolism of fats, proteins, nucleic acids and carbohydrates.

It should also be noted that the microelement under consideration affects neuromuscular excitation, thereby inhibiting neuromuscular transmission.

Magnesium is a natural physiological antagonist of an element such as calcium. It controls the normal functioning of myocardial cells, and also participates in the regulation of its contractile function.

In stressful situations, free ionized magnesium is excreted from the body in increased amounts, and its additional reception increases resistance to stress.

Lack of magnesium

The drug "Magnesium Orotate" is intended to fill the deficiency of the most important trace element in the body. The lack of this substance contributes to the development of neuromuscular disorders( including seizures, increased sensory and motor excitability, paresthesia), cardiovascular diseases( including tachycardia, ventricular extrasystole, hypersensitivity to cardiac glycosides) and psychological changes( confusion, depression and hallucinations).It should also be noted that during pregnancy, magnesium deficiency increases the risk of premature birth and toxicosis.

One can not help saying that the salts of orotic acid take an active part in the metabolism process. They are also necessary for the manifestation of the action of magnesium and its fixation on ATP in cells.

Kinetics of

After taking a single dose of the "Magnesium Orotate" preparation, approximately 35-40% of the blood is absorbed into the system. In this hypomagnesemia stimulates the absorption of magnesium ions, and the presence of salts of orotic acid significantly improve this process.

Magnesium is excreted from the body through the kidneys. If this element is deficient, its excretion decreases, and in excess, it increases.

Indications

Under what conditions can a patient be assigned "Magnesium Orotate"?According to experts, this drug should be taken with:

• atherosclerosis;
• heart rhythm disturbances, including ventricular arrhythmia in people with digital intoxication;
• arteritis;
• angina;
• acute myocardial infarction( for the purpose of preventing arrhythmias);
• of dyslipoproteinemia;
• alcoholism, the state of withdrawal syndrome;
• cachexia.

It should also be noted that "Magnesium Orotate" is very often recommended for those whose diet is low in protein, as well as a low calorie content.

This agent is actively used to fill the lack of magnesium. Usually, this deficit is observed with breastfeeding and pregnancy, as well as hyperthyroidism, hypercalcemia, hyperaldosteronism, decreased intake and assimilation of the element, its increased excretion from the body, which is associated with impaired renal function, chronic diarrhea, and so on.

Contraindications

Magnesium preparation is contraindicated for taking in conditions such as:

• increased sensitivity;
• impaired renal function;
• liver damage of a chronic and acute nature;
• is a urolithic disease, in which magnesium-calcium and phosphate stones are observed;
• state of AV and sinoatrial block.

Preparation "Magnerot": instruction for use

The price of this remedy will be indicated below.

According to the instructions, the preparation in question is intended for oral administration. To significantly improve the effectiveness of this medication, it is recommended to take it 60 minutes before meals. Tablets should be washed down with plenty of liquid.

The duration of a conservative course of therapy should be determined by the attending physician in each individual case. Although the instructions indicate the general scheme of reception.

At the very beginning of treatment for magnesium deficiency, experts recommend using two tablets of the drug three times a day( for a week).After that, the dosage is reduced to one tablet at a time.

The maximum daily dose of this agent is 3000 mg( ie 6 tablets).

People suffering from nocturnal seizures, this drug is usually prescribed in an amount of 2-3 tablets before bed( one-time).

Side effects of

What side effects can Orotat Magnesium cause? Customers' reviews say that this remedy is well tolerated by them. Although with self-administration of medication in large doses nevertheless possible dyspeptic disorders of the gastrointestinal tract, which are manifested by instability of the stool and diarrhea. Such unpleasant symptoms are stopped by reducing the once-only dose of the drug.

It should also be noted that there are clinical cases when, against the background of taking the magnesium preparation, skin allergy developed in the form of characteristic exanthema, urticaria, papular and hyperemic rashes, itching. The appearance of such signs requires immediate contact with the attending physician to adjust the dose taken.

Interaction of

Is it possible to combine the preparation "Magnerot" with other agents? Instructions for use( the price of this medication is not very high) claims that this medication is forbidden to combine with iron salts, tetracyclines and sodium fluoride, as the intestinal reabsorption of the latter is significantly reduced.

In parallel use of magnesium with neuroleptics, sedatives or tranquilizers, their pharmacological action is potentiated.

With the combination of "Magnnerot" with antihypertensive and antiarrhythmic drugs, the intensity of their therapeutic effect increases( it is possible the development of bradycardic or hypotensive crises).

Similar drugs and the price of the drug

You can replace the medicine in question by means such as "Panangin" and "Asparcum".Also in pharmacy chains, there are many other vitamin complexes that contain magnesium.

As for the price, then you can buy this drug for 160-180 rubles.

Reviews about

Consumer reviews about this drug indicate its positive effect on the human body. Patients claim that after taking "Magneterot" their general condition became noticeably better.

Many experts are pleased with this tool. They report that its use significantly reduces the risk of developing coronary artery disease. This fact is confirmed by numerous statistical data.

Also about the drug "Orotat Magnesium" leave their reviews and pregnant women. They argue that taking this remedy has eliminated nighttime convulsions, and also reduced irritability and nervousness. However, doctors report that taking this medication while bearing the fetus should be done only under the supervision of a qualified doctor.