Rheumatoid factor: the norm in women, deviations
Rheumatoid factor is a group of autoimmune antibodies, newly formed and synthesized immunoglobulin proteins that attack their own organism, perceived by them, in turn, as foreign bodies. In other words, the rheumatoid factor is a protein that is modified by infection, bacteria or viruses. The positive rheumatoid factor( norm) in women over 18 years is from 0 to 14 units / ml. Normal indicators for adolescent girls are slightly lower than in adult women: 0 to 12 U / ml.
The formation of a rheumatoid factor occurs as a result of a human beta-hemolytic streptococcus entering the bloodstream, and usually its presence indicates that the body is suffering from an autoimmune or inflammatory disease. But not every patient has an increased content of rheumatoid factor, only a fifth of those infected with beta-hemolytic streptococcus have its increased content.
Norm and excess
If the person is healthy, the rheumatoid factor( the norm in women) is 10 units / ml. This is an indicator included in the normal amplitude from 0 to 14 U / ml. But even if the value of rheumatoid is increased, this does not guarantee the mandatory presence of the disease. This situation is just the basis for a more detailed examination: ultrasound, radiography, analyzes for the presence of C-reactive protein in the blood.
As well as the absence of a rheumatoid, its detection does not necessarily indicate the presence of an autoimmune disease, it can indicate viral diseases, cancer, tuberculosis, and even the presence of immunoglobulins in the body of a woman who has recently undergone childbirth. In all these cases, the rheumatoid factor( the norm in women) is negative. This will indicate the analysis, but this situation does not always indicate that the body is healthy.
Causes of increased rheumatophagor
There are many different theories and assumptions for what reason in the blood there is an increase in rheumatoid factor. One of them is the assumption about the genetic character of the disease, when the rheumatoid factor( the norm in women is from 0 to 14 U / ml) is transmitted by inheritance and manifests itself upon exposure to the body of various infections and viruses.
Rheumatoid arthritis and Sjogren's disease
The most common phenomenon is when the rheumatoid factor can be stabilized only after a course of prolonged systemic therapy. The norm in women( treatment is able to help in this) is necessarily restored to the values from 0 to 14 units / ml. Whichever diagnosis is made: rheumatoid arthritis or Sjogren's syndrome - from properly performed medical measures, the rheumatoid will return to normal limits.
Diseases such as rheumatoid arthritis and Sjogren's syndrome are characteristic of elderly people. In the first case, the patient is observed inflammation of the joints, dry mucous membranes and skin, in the second - the dysfunction of the glands of internal secretion. Rheumatoid arthritis is also characterized by the appearance of nodular neoplasms and difficulty in the motor activity of the joints.
Analyzing the rheumatoid factor
On the eve of the analysis for the presence of rheumatoid factor the patient is obliged to conduct a set of preparatory measures: at least 24 hours not to smoke, do not engage in manual labor, do not consume alcohol and fatty foods. And for eight to twelve hours, do not take any food, except for pure non-carbonated food.
Assignment of an analgesic for a rheumatoid usually occurs if a woman who has recently given birth for a long time complains of a sore throat. In such a case, the fence of venous blood is made, the analysis of which determines the indices of the rheumatoid factor in the body. In this case, if the value is from 25 to 50 IU / ml, then it is considered slightly elevated if 50-100 IU / ml - stably increased, and more than 100 IU / ml - greatly increased. To confirm the diagnosis, there are usually three or more additional studies that must confirm or disprove the result of a blood test. Only in this case can rheumatoid arthritis or Sjogren's syndrome be diagnosed. It should be remembered that the treatment of these diseases is a matter for a graduate. Taking self-medication or following the advice of semi-literate people in this case will be detrimental to the health of the patient.
Reduction of the rheumatophagor
If the examination showed that the rheumatoid factor( the norm in women in MED / ml is from 0 to 14) is increased, steps should be taken not to reduce the rheumatoid factor, but to eliminate the reasons for its increase. That is, it is necessary to treat not a symptom, but a disease that caused it. Usually the patient undergoes treatment with antibiotics, anti-inflammatory medications or steroid hormones.
Treatment should last until the moment the rheumatoid factor index has reached the norm. During therapy, the patient also must follow certain rules: do not smoke, do not drink alcohol, do not overcool, protect yourself from contact with sick people, temporarily get rid of physical exertion, eat healthy foods and consume multivitamin complexes. These precautions will help to strengthen and improve the body.
Symptoms of rheumatoid arthritis usually appear long before the rheumatopharyngeal rises( about 6 to 8 weeks earlier), so an analysis performed at an early stage of the disease may not show an increased value.
Low rheumatic factor indices are characteristic of such diseases as infectious mononucleosis, acute inflammatory processes, consequences of multiple blood transfusions in a woman who has undergone multiple births.
Elevated rheumatic factor is also observed in cases of red systemic lupus erythematosus, periarthritis of nodular, dermatomyositis, liver cirrhosis, scleroderma, hepatitis and( in 60% of cases) with bacterial endocarditis occurring in subacute form.
Revmofactor in patients with rheumatism
It is noteworthy that most people suffering from rheumatism have a normal rheumatoid factor. The increased value of the indicator is most often observed with repeated diseases. It can also be increased in healthy people, which will indicate the person is at risk. There are cases when an increased rheumatic factor was detected several years before the development of the disease.
In order to prevent the increase in rheumatoid factor, it is recommended to lead a healthy lifestyle, reduce salt intake to a minimum, eat plenty of fruits and vegetables, do not consume alcohol or smoke. It is very important in order to avoid an increase in the ravmatoid factor in a timely manner to treat the diseases, if they exist, and if possible to prevent their transition to the chronic stage. Rise of the rheumatoid factor may also be caused by regular hypothermia and infectious diseases, so they should be avoided.