"Dorzopt Plus": instructions for use, reviews, composition, analogues

Do you know what constitutes a disease such as glaucoma? According to specialists, for this disease is characterized by a periodic or regular increase in pressure( intraocular) with subsequent optic nerve atrophy, the development of visual field defects and a decrease in its severity. dorsopt plus instructions for use

Today, there are many drugs that can cure this disease. One of them includes the drug Dorzopt Plus. Instructions for use, analogs, the form of release of this tool will be presented below.

Form of the preparation, its composition, description and packaging

In what form are the medicines manufactured by Dorzopt Plus? Instruction for use asserts that this agent is produced in the form of drops for the eyes, which are a colorless, transparent and slightly viscous solution.

The active ingredients of this drug are dorzolamide hydrochloride and timolol maleate. As auxiliary components, the solution contains hyetylose, monohydrate of citric acid, benzalkonium chloride, purified water, sodium hydroxide, mannitol and hydrochloric acid.

To buy the drops of Dorzopt Plus, the composition of which was presented above, it is possible in polymer bottles-droppers, which are placed in packs of cardboard.

Pharmacology

How do eye drops "Dorzopt Plus" work? The instruction states that this antiglaucoma means containing two active components, each of which reduces the increased pressure( intraocular).This is due to a decrease in the secretion of the intraocular fluid.

Consider the properties of the active substances of the preparation in more detail. dorsopt plus composition

Dorzolamide is a selective inhibitor of carbonic anhydrase. This component reduces the secretion of the aqueous humor. According to specialists, this effect is due to a decrease in the formation of hydrocarbonate ions, which ultimately leads to a slowdown in the transport of sodium and intraocular fluid.

As for timolol, this is a non-selective beta-blocker. Its principle of action has not yet been studied.

After application of the drug, the decrease in intraocular pressure is observed after 20 minutes and lasts for a day.

Kinetics of

Do Dorzopt Plus drops suck in the systemic bloodstream? The instruction says that the kinetics of the active substances of this drug can vary considerably.

Dorzolamide penetrates the eye through the cornea. Its systemic absorption is very low. When a substance enters the blood, it quickly penetrates into the erythrocytes.

The relationship of dorzolamide with plasma proteins is 33%.Dorsolamide is excreted by the kidneys for 4 months. dorsopt plus instruction on the use of analogues

Timolol is also absorbed into the systemic circulation. Its concentration in plasma is noted only with double application per day.

Indications

In what cases is the drug "Dorzopt Plus" prescribed? Instructions for use inform that this remedy is used with increased intraocular pressure, which is observed when:

  • glaucoma is pseudoexfoliation;
  • glaucoma is an open-ended.

Contraindications

Are there any contraindications to drops of Dorzopt Plus? Instruction for use indicates the following prohibitions:

  • shock cardiogenic;
  • time of breastfeeding;
  • asthma is bronchial;
  • severe heart failure;
  • obstructive chronic lung disease of severe severity;
  • sinus bradycardia;
  • gestation period;
  • AV-blockade of the third and second degree;
  • processes of a dystrophic nature in the cornea;
  • severe renal failure;
  • is a minor age;
  • hypersensitivity to elements.

dorsopt plus instructions for use reviews

When using the drug, special care should be taken for people with liver failure, in old age and with diabetes.

Eye drops "Dorzopt Plus": instructions for use

Reviews of the local medicine will be presented below.

The drug in question is instilled in the conjunctival sac 1 drop twice a day.

If several local ophthalmic agents are used during therapy for glaucoma, then instillations are carried out at an interval of 10 minutes.

The duration of treatment with this drug is determined by the doctor, depending on the patient's condition.

Side effects

Eye drops "Dorzopt Plus", the instruction of which is enclosed in a cardboard package, can cause undesirable reactions.

eye drops dorsopt plus instructions

Due to the presence of dorzolamide in the preparation, the following side effects occur:

  • lachrymation, inflammation of the eyelid, peeling and irritation of the eyelid, spot keratitis, iridocyclitis, pharyngeal irritation, transient myopia, which passes after drug withdrawal;
  • dry mouth, angioedema edema, rash;
  • urticaria, bronchospasm, pruritus;
  • nosebleeds, headaches, asthenia, paresthesia, fatigue.

With regard to an active substance such as timolol, it provokes the following reactions:

  • conjunctivitis, blepharitis, paresthesia, keratitis, decreased corneal sensitivity, heart rhythm disturbances, changes in eye refraction, ptosis, diplopia;
  • ringing in the ears, headache, dry eye syndrome, memory loss, asthenia, nightmares, fatigue, depression, dizziness, signs of myasthenia grazing, insomnia;
  • Raynaud's syndrome, visual disturbances, fainting, arrhythmia, cardiac arrest, lowering blood pressure, swelling, lowering the temperature of the legs and hands;
  • bronchospasm, chest pain, cough;
  • alopecia, exacerbation of psoriasis, psoriasis-like rash;
  • anaphylaxis, urticaria, angioedema, generalized or localized rash;
  • diarrhea, dry mouth, indigestion;
  • decreased libido, systemic lupus erythematosus, Peyronie's disease.

Cases of overdose

What are the symptoms of an overdose of Dorsopt Plus? Instruction for use reports such reactions as dizziness, bronchospasm, headache, bradycardia, dyspnea and cardiac arrest.

Acidosis, electrolyte imbalance, asthenia, paresthesia and fatigue can also develop.

In such conditions, maintenance therapy is provided. drozopt drops plus instructions

Drug Interactions

No studies have been conducted on the interaction of the drug in question with other drugs. Therefore, the combination of drops Dorzopt Plus with other means follows only after consultation with the doctor.

Special recommendations

Before prescribing the drug for the eyes, Dorzopt Plus should provide the patient with adequate monitoring of the condition of the heart and the vascular system. People with pathologies in this area should be under the constant supervision of specialists.

This medication contains a preservative of benzalkonium chloride. It can settle on soft contact lenses and have a damaging effect on the tissues of the visual organs. Therefore, people who use eyesight improving drugs should remove them before using drops and install only after 20 minutes after instillation of the drug.

With extreme caution, Dorzopt Plus is prescribed for people with diabetes mellitus. This is due to the fact that beta-adrenoblockers mask the signs of acute hypoglycemia.

Before the planned surgical procedure, it is required to gradually cancel the drug two days before the general anesthesia, since beta-blockers can enhance the action of muscle relaxants. Analogues of the drug and its cost

How can I replace Eye Drops Dorzopt Plus? His analogues are Trusopt and Floksal. However, these funds should be used only for the purpose of a specialist.

The cost of this drug is quite high. In the pharmacy it can be purchased for 400-450 rubles. dorsopt plus instructions

Reviews of eye drops

There are not very many consumer reviews of the drug in question. The advantages of this drug include high efficiency and effectiveness, as well as accessibility( sold in virtually any pharmacy).

It should also be noted that drops of "Dorzopt Plus" also contain negative responses from patients. Many of them complain that after using a local remedy, local or systemic side reactions often develop. Therefore, experts do not recommend using the above medication alone. To achieve the best therapeutic result, it should be prescribed only by an experienced doctor. Only with a properly selected therapy scheme, side effects can be avoided.