"Kofetamin": instructions for use, analogs, photos, reviews

Migraine is a neurological disorder characterized by regular or episodic painful and severe pain attacks that occur in one half of the head. This condition of the patient is not associated with serious injuries, stroke or brain tumor. The pulsating nature and intensity of the pains are explained by the presence of vascular pathologies, and not by excessive strain of the patient.

It should also be noted that headaches with migraine are not associated with a sharp decrease or increase in blood pressure, an attack of ICP or glaucoma.

For the treatment of this condition, many specialists recommend using the drug "Kofetamin".Instructions for use, photo medications, reviews about it, similar tools and properties are presented below.

Composition of the drug, its form of release and packaging

What form does the drug "Kofetamin" have? Instructions for use, reviews indicate that this drug is on sale in the form of tablets. They include ingredients such as ergotamine tartrate, potato starch, stearic acid, talc, caffeine, glucose and sugar.

In the sale of medicines comes in contour mesh packaging.

Pharmacodynamic features of the drug

What is remarkable about the tablets "Kofetamin"?Instructions for use indicate that this is a combined product, the effect of which is due to the properties of the constituent ingredients.

Caffeine promotes stimulation of the vasomotor and respiratory centers, and also increases excitation of the cerebral cortex. In addition, this substance has a cardiotonic effect. It slightly increases blood pressure, and also increases the frequency of respiration and heartbeats. Also, caffeine reduces drowsiness, stimulates motor activity, eliminates the feeling of fatigue, improves overall performance.

The severity and duration of action of this component depends on the person's condition, the type of nervous system and the activity of the whole organism.

In small doses, caffeine has a stimulating effect, and in large doses it has a depressing effect on the central nervous system.

As for ergotamine, it has a vasoconstrictive effect.

Kinetic features of

Where does the absorption of such a drug as "Cofetamine" occur? Instructions for use indicate that this drug is quite good and very quickly absorbed from the intestine. Ergotamine binds 98% to plasma proteins, and caffeine - by 35%.

The highest concentration of this drug in the blood is observed 2 hours after taking the pill. Most of the caffeine is oxidized and demethylated, and then excreted along with the urine.

The metabolism of ergotamine is carried out in the liver with the formation of active derivatives.

This drug is excreted mainly with bile within five hours.

Indications for taking medication tablets

Do you know about the purpose for which the drug "Kofetamin" can be prescribed? Instruction, reviews report that such a drug is very effective in the vaso-paralysis of migraine, arterial hypotension, as well as vascular, infectious and traumatic lesions of the central nervous system, is used to reduce intracranial pressure.

Prohibitions for the use of the drug

When should you not prescribe the drug "Kofetamin"?The instruction( analogues of the medication are listed below) informs that this drug is forbidden to be taken at high sensitivity to the drug, as well as during the period of gestation and during lactation.

With caution, this medication is used for severe sleep disorders, arterial hypertension, vascular and heart disease( eg, angina pectoris, severe atherosclerosis, paroxysmal tachycardia, myocardial infarction, peripheral vascular disease), glaucoma, anxiety and panic disorder, kidney or liver disease,agoraphobia and in old age.

Drug "Kofetamin": instructions for use

Analogs of this medicine should be prescribed only by a doctor. This is due to the fact that they can have completely different forms of output and methods of application.

This medication should be used during severe attacks of headache. In this case, it is prescribed in the amount of 1-2 tablets twice a day. After that, for several days, the medication is taken with 1 tablet with the same multiplicity.

It is strictly forbidden to exceed the maximum single dose of the drug equal to 2 tablets and the daily dose equal to 4.

It should also be noted that the drug should not be taken for a long time. After a week of taking the drug, you need to take a break for 4 days.

Side effects of

What are the possible side effects to be aware of before taking Cofetamine tablets? The instruction of this drug reports that it can cause the following reactions:

• cardialgia, dizziness, hypertension, agitation;
• tachycardia, headache, restlessness, itching, anxiety, tremor, reflex intensification, nausea, insomnia;
• diarrhea, cramps, vomiting, paresthesia in the extremities, swelling.

With prolonged medication, it is possible to develop myalgia, a general sensitivity disorder in the lower limbs, and weakness.

Overdose and drug interaction

What signs of an overdose occur when taking higher doses of a drug such as Cofetamine? The instruction for use says that in this case the patient manifests: drowsiness, nausea, block, vomiting, numbness of the upper and lower extremities, stupor, as well as epileptic seizures and coma. To eliminate such phenomena, gastric lavage is performed. Also, the patient is assigned activated charcoal.

This medication enhances the effect of drugs that include ergot alkaloids and caffeine. When it is combined with barbiturates and anticonvulsants, caffeine clearance is increased and its metabolism is accelerated.

Nicotine promotes rapid drug excretion, and CNS stimulants - excessive excitability.

This medication reduces the effect of hypnotics, narcotic analgesics, and also increases the toxicity and absorption of cardiac glycosides and non-narcotic analgesics.

Joint reception of caffeine with beta-blockers often leads to mutual suppression of their therapeutic effects, and with adrenergic bronchodilators - to stimulation of the CNS and other additive toxic reactions.

It should also be noted that the active substance of this drug can reduce the clearance of theophylline and other xanthines.

The vasoconstrictor action of this medication is enhanced by beta-blockers, alpha-adrenostimulators, nicotine and serotonin agonists.

The toxicity of ergotamine increases macrolides.

The cost of the drug and similar drugs

You can buy this product in the amount of 10 tablets for 100-150 rubles. If required, it can be replaced with such analogous drugs as Cofergot, Ergofain, Nomigren, Ergoffin. However, before this, you should always consult a doctor.

Reviews of specialists and patients

Now you have an idea of ​​how the drug "Kofetamin" works. Instructions for use of this agent have also been described above. Reviews about him are mostly positive. Those people who use this remedy say that it works effectively with a strong migraine. Such a drug is more effective than other, more expensive drugs. Consumers report that they only need to take two tablets a day. This dosage immediately stops pain. Although sometimes unpleasant feelings remain even after taking the medicine. But in this case they are not very pronounced.

The negative sides of this remedy include a large number of adverse reactions that appear against the background of its administration.