"Spytomin" preparation: instructions for use, indications, contraindications

Today we will tell you about such a preparation as "Spitomin".Instructions for use, price, reviews, analogues and its features - all these points are of interest to patients to whom the doctor prescribed this medicine. You will find all the necessary information in the article.

Description of the medicine, its form, packaging and composition.

What is Spitomin medication? Instructions for use( the description of the drug in it is presented in great detail) states that these tablets are white, odorless, round and flat, with a facet, and also with a risk and engraving "E151".

This agent contains buspirone hydrochloride and such auxiliary components as carboxymethyl starch, lactose monohydrate, sodium magnesium stearate, microcrystalline cellulose and colloidal anhydrous silicon dioxide.

This medicine is on sale in blisters and cardboard packs.

How does the

work? What are the features of the Spitomin drug? Instructions for use( the price of tablets is presented below) states that this is an anxiolytic agent that belongs to the non-benzodiazepine series and has an antidepressant effect.

Unlike other anxiolytics, this drug does not have antiepileptic, sedative, hypnotic and muscle relaxant properties. Its principle of operation is based on the effect of buspirone on the dopaminergic and serotonergic systems.

This drug selectively blocks dopamine receptors( presynaptic) and increases the excitation rate of neurons( dopamine) of the midbrain.

What other properties are inherent in the drug "Spitomin"?The instruction for use asserts that buspirone is a selective partial agonist of 5-HT1A-serotonin receptors. It does not affect benzodiazepine receptors and GABA binding, nor does it affect psychomotor functions and does not cause tolerance. In addition, this agent does not potentiate the effect of alcoholic beverages.

The therapeutic effect of the drug in question develops gradually and is observed one or two days after the start of treatment.

Kinetics of

The absorption of the preparation "Spitomin", the instructions for use of which is presented below, occurs in the digestive tract. Buspirone is extensively metabolized when passing through the liver. Its bioavailability is 4%, and the highest concentration in plasma is reached after an hour.

Buspirone excreted together with milk. Information about the penetration of this drug through the placental barrier is absent.

A drug with feces is excreted for five hours.

Indications

What is the purpose of the Spitomin tablets? Instructions for use indicate the following indications:

• autonomic dysfunction syndrome;
• anxiety disorder generalized;
• withdrawal syndrome alcoholic( in the form of ancillary therapy);
• panic disorder;
• depressive disorders( in the form of adjuvant therapy).

Contraindications

When is it not recommended to use tablets "Spitomin"?Instructions for use indicate the following pathologies and conditions in which the medication is contraindicated:

• glaucoma;
• hypersensitivity to the ingredients of the medication;
• myasthenia gravis;
• renal failure severe;
• is a minor age;
• simultaneous administration of MAO inhibitors;
• lactation period;
• gestation period.

With caution, this agent is prescribed for cirrhosis of the liver and kidney failure.

Spitomin medication: instructions for use

Analogs of this drug will be presented below.

The agent should be taken at the same time of the day, before or after a meal.

The drug should not be used occasionally( on demand) to treat anxiety, as its therapeutic effect develops only after repeated use.

The dosage of this medication is selected individually. As a rule, it is 15 mg. It should be divided into 2-3 sessions.

The maximum single dose of the drug is 30 mg, and the maximum daily dose is 60 mg.

In elderly people, dose adjustment is not required. In case of impaired renal or hepatic function, the medication should be used with extreme caution and in small doses.

Side effects of

The drug Spitomin is usually well tolerated. Only in some cases this drug causes certain disorders:

• chest pain, sleep disorders, fainting, dizziness, arterial hypotension, headache, hypertension;
• nervous excitability, cerebral circulation disorders, dysphoric reactions, decompensation of heart failure, hypersensitivity to noise, myocardial infarction, dysphoria, myocardiopathy, suicidal ideation, bradycardia;
• depersonalization, cold intolerance, euphoria, claustrophobia, hyperkinesia, tinnitus, fear, itching in the eyes, apathy, redness of the eyes, hallucinations, stammering, confusion, psychotic disorders;
• blurred vision, laryngitis, conjunctivitis, edema of the nasal mucosa, impaired taste, chest heaviness, inner ear disorders, hyperventilation, eye pain, lack of air, photophobia, epistaxis, increased intraocular pressure;
• galactorrhea, nausea, thyroid damage, flatulence, bedwetting, anorexia, increased appetite, dysuria, salivation, menstrual irregularities, intestinal bleeding, delayed ejaculation, and others.

Price, analogues, reviews

The cost of this tool is about 600 rubles. If required, it is replaced by an analog such as Buspiron Sandoz.

Consumer reviews report that the drug in question is a good anxiolytic. However, it can only be taken for the purpose of a specialist, for a long time( not sporadically).