"Glyformin" in diabetes mellitus: price, reviews and analogues
The preparation "Glyformin" belongs to the biguanide group. It is a hypoglycemic medication that reduces glucose absorption and simultaneously increases the sensitivity of some tissues to insulin. From the materials in this article, you will find out which dosage is prescribed for "Gliiformin" in diabetes mellitus, the cost of the drug and the responses of real patients.
Composition and Form of Release
The drug is commercially available in the form of tablets, which can be of two types:
- Ploskotsilindricheski pills with a separation facet of white color( 0.5 g of active substance).Packed in 10 pieces per cell pack.
- Pills in a film coat of cream shade( 0.85 or 1 g of active substance).Packed in polypropylene jars of 60 pieces.
The active ingredient is metformin hydrochloride.
Pharmacological action of
"Glyformin" in diabetes should be taken solely orally. The mechanism of the effect of the drug on the systems of internal organs has not been studied to the end.
Penetrating into the body, the active substance is involved in the following processes:
- Suppression of the formation of glucose molecules in the liver.
- Activation of carbohydrate cleavage.
- Reduces the volume of glucose from the intestine.
The use of the drug "Glyformin" in diabetes and obesity leads to a decrease in appetite, body weight. The instructions state that the medication promotes the gradual dissolution of blood clots and prevents the adhesion of platelets.
Metformin hydrochloride is rapidly absorbed by the GIT cells. The limiting concentration of active active substance is fixed after two hours from the moment of admission. Its bioavailability is approximately 50-60%.The drug does not come into contact with plasma proteins, it gradually accumulates in the systems of internal organs. From the body the substance is taken out practically unchanged.
Indications for the use of the drug "Gliiformin"
Tablets instructions for use recommend taking patients with the following pathologies:
- Type II diabetes mellitus when dietotherapy and sulfonylurea drugs are ineffective.
- Type I diabetes mellitus( supplement to standard insulin therapy).
During the treatment, constant monitoring of the kidneys is necessary, once every six months it is recommended to check the lactate values in the blood plasma.
How to use
In what dosage is Glioblast prescribed for diabetes mellitus? According to the instructions, the tablets should be taken during / after meals, and they should be taken with water. Specific dosage and duration of treatment is prescribed by the doctor, taking into account the glucose values in the patient's blood.
At the initial stage of therapy( the first 15 days), the dosage is no more than 1 g per day. Then it is gradually increased. The maintenance dose usually does not exceed 2 g per day. It is evenly divided into several receptions.
For patients of advanced age, the daily dose of the drug is not more than 1 g.
When the doctor prescribes "Gliiformin" in diabetes, reviews of real patients allow you to evaluate the effectiveness of the drug. Like other medicines, it can cause a number of side effects:
- Endocrine system: hypoglycemia.
- Circulation: anemia.
- Allergic reactions: rashes, hives.
- Metabolism: hypovitaminosis.
- Gastrointestinal system: lack of appetite, nausea, metal taste in the mouth, vomiting, diarrhea.
If side effects occur, you must stop taking the pills for a while and consult a doctor.
The instructions to the drug say that its administration is not recommended in the following conditions:
- diabetic coma;
- pulmonary / congestive heart failure;
- chronic liver disease;
- myocardial infarction;
- hypersensitivity to the constituents of the preparation;
- pregnancy and lactation.
With extreme caution, use "Gliiformin" from diabetes mellitus in pathologies of infectious nature, before serious operations.
According to the instructions, with the simultaneous use of insulin, nonsteroidal anti-inflammatory drugs, sulfonylurea derivatives, beta-blockers, the action of "Glyformin" is not excluded.
Its effectiveness can be significantly reduced by additional treatment with glucocorticosteroids, oral contraceptives, thyroid hormones, nicotinic acid derivatives, diuretics.
Price and storage conditions
The medicine should be stored at a temperature of up to 25 degrees in a place protected from children. Shelf life is 3 years, and for tablets in a film sheath - 2 years.
How much does "Gliiformin" cost? With diabetes, the price of medicines plays an important role for many patients. The medicine described in the article is relatively inexpensive. For the packing of tablets in a film shell, you will have to give a little more than 300 rubles. Pills with a separating chamfer( 0.5 g of active substance) are cheaper - about 150 rubles.
When the Gliiformin drug is purchased, the application, instruction, feedback is the first thing that patients pay attention to. Due to a wide range of contraindications, many medications are not suitable. You can choose a drug similar in pharmacological properties after consulting a doctor.
Among the analogues that most correspond to "Gliformin" in the active substance content, the following are distinguished: "Diabetic", "Metformin", "Glucoran".
Reviews of Patients and Physicians
Many patients who have been assigned this medication for treatment note a high likelihood of an overdose. In most cases, it is caused by improper use of the medication. Overdose can trigger the occurrence of so-called lactic acidosis. His main symptoms are: pain in the muscles, vomiting and nausea, impaired consciousness. If the patient has such signs, it is recommended to stop taking the medication and seek help from a doctor.
On the part of specialists, reviews are in most cases positive. This is why Gli-formin is often prescribed for diabetes mellitus. The medication price is low, it can be purchased in almost every pharmacy. If you follow the instructions clearly, the likelihood of side effects is low. Doctors warn that throughout the course of treatment 2-3 times a year must be tested for serum creatinine. During therapy, alcohol and medication should be dispensed with ethanol.
Diabetes mellitus is a fairly common disease, which is increasingly diagnosed today in young people. For his treatment, doctors prescribe various medications."Gliiformin" also refers to their number. It is a hypoglycemic medication responsible for increasing the sensitivity of tissues to insulin. If you take it in accordance with the instructions and on the prescription of the doctor, there should not be side effects. It is equally important to take into account the contraindications of the drug.