"Neobutin": instructions for use, analogues, reviews

According to the instructions for use, "Neobutin" is a drug that regulates the peristalsis of the gastrointestinal system. It performs the function of stimulating the smooth muscles of the intestine, exerting an antispasmodic effect. We will consider in more detail its instructions for use, learn about what analogues exist, and also get acquainted with the opinions of patients who already have experience of treatment with this pharmaceutical product.

Description of the preparation

Trimebutin, acting as the active substance of this drug, exerts its influence on the enkephalinergic system of the intestine and serves as a regulator of its peristalsis. By influencing peripheral receptors, including those located directly in the smooth muscles of the entire gastrointestinal tract, it regulates the process of motor activity without directly affecting the operation of the central nervous system. So, the substance of trimebutin completely restores the necessary physiological activity of the musculature of the intestine against the background of various diseases of the digestive organs that are associated with motor disorders.

Normalizing the sensitivity to visceral function, according to the instructions for use, "Neobutin" provides an analgesic effect against the background of abdominal pain syndrome. The composition of this medicine, in addition to tri -butine maleate, also includes other auxiliary substances.

Pharmacokinetics of medical preparation

After the use of the drug inside, "Neobutin" is able to be absorbed quickly enough from the gastrointestinal tract. The bioavailability of the drug is four to six percent. At the same time, the binding index of plasma proteins is low and reaches about five percent. Trimebutin is insignificantly able to penetrate the placental barrier. This element undergoes the process of assimilation in the liver, and is excreted by the kidneys, which occurs primarily in the form of metabolites in a volume of seventy percent during the first twenty-four hours.

Indications for use of "Neobutin"

This medicine is prescribed by doctors for disorders of motility of the gastrointestinal tract against the background of the following functional diseases and conditions:

• Presence of gastroesophageal reflux disease.
• The existence of dyspeptic disorders in the face of gastroduodenal diseases, such as abdominal pain, digestive disorders, attacks of nausea and vomiting.
• Syndrome of irritation of the intestine, which is manifested by pain and colic in the abdominal cavity, and is accompanied by intestinal spasms, diarrhea, flatulence and constipation.
• In the postoperative period with paralytic intestinal obstruction.
• In case of preparation for radiographic or endoscopic examination of digestive organs.
• Against the background of dyspeptic disorders associated with gastrointestinal motility disorder in children.

This is confirmed by the instruction on the application of "Neobutin".

Forms of the release of "Neobutin"

The drug is released in the form of tablets of 100 milligrams, which have a prolonged effect. The tablets are coated.

Instructions for the use of the drug "Neobutin" and the methods of its dosage

The drug "Neobutin" is consumed inside before eating. Adults, as well as children over the age of twelve, should consume 100-200 milligrams three times a day. In order to prevent the occurrence of relapse of the irritated bowel after the necessary course of treatment during remission, doctors recommend to continue taking this drug in the amount of 300 milligrams per day for twelve weeks. Children under the age of twelve must use 50 milligrams three times a day. Very small in the age of up to five years can take 25 milligrams three times a day.

This is indicated by the instruction on the use of "Neobutin".

Side effect of

The following side effects are likely to occur when taking this medication:

• Dry mouth, accompanied by unpleasant taste sensations.
• Appearance of diarrhea, constipation, dyspepsia and nausea.

• Feeling of drowsiness, fatigue, severe dizziness, and also a feeling of anxiety and anxiety.
• Short-term syncope.
• Feeling of heat and cold.
• Appearance of skin rashes.
• Violation of the menstrual cycle in women, and in addition, tenderness and enlargement of the mammary glands.
• Urine retention.

This is confirmed by the instructions for use and feedback on "Neobutin."

Contraindications to the use of the drug "Neobutin"

Do not use this tool if the following factors exist:

• Lactose intolerance to patients.
• The presence of glucose-galactose malabsorption.
• Pregnancy period.
• Children under three years of age, when it comes to tablets.
• Hypersensitivity of the body to the substance trimebutin.

Application of "Neobutin" during pregnancy and breastfeeding

No experimental data on embryotoxicity and teratogenicity of trimebutin were found during the experimental studies. But nevertheless, in view of the fact that the necessary clinical information is not available, the use of "Nesutin" tablets( the instruction for use confirms this) during pregnancy is completely contraindicated.

Specialists do not recommend the use of the drug during breastfeeding because of the lack of reliable clinical information that would confirm the safety of the use of the drug at this time.

Use of the drug for children

According to the instructions for use, "Neobutin"( photo of the drug is available in the article) in the form of tablets is strictly contraindicated for children under the age of three. For those who are older, the dose is determined depending on age.

Special instructions for the use of

In the course of treatment of irritable bowel syndrome during its acute manifestation, it is possible to take a drug in the amount of 600 milligrams per day for four weeks. Also, you can continue treatment after the performed phase, reducing the dose twice. As part of the continuation of the drug taken within twelve weeks, which significantly reduces the risk of recurrence of the disease.

Influence of "Neobutin" on the ability to drive vehicles and other mechanisms of

Taking into account possible side effects such as dizziness and other factors, one should refrain from driving and other potentially hazardous activities.

This describes the instructions for the application to "Neobutin".Price and reviews of doctors will be presented below.

Analogues

The structural analogs of "Neobutin" are referred to as "Retard" and "Trimedat" according to the active substance.

Analogues on the curative effect that help in the treatment of irritable bowel syndrome are Bactistatin, Guttalax, Dicetel, Irmalax, Lactofiltrum, Mukofalk, Spasmonet, Fitomycil and others.

We have reviewed the instructions for use and analogues for "Neobutin".

Reviews

With regard to the feedback on "Neututine" we can say that people basically report a fairly good portability of the product. This medication is able to quickly relieve the pain, stabilizing the work of the intestine.

Patients in their comments share that soon after receiving "Neobutin" felt a noticeable relief, which came in a few days. Such patients, as a rule, are constantly tormented by flatulence. People are afraid to eat, because, whatever they eat, they begin to twist their stomachs and, in addition, something continually hears something in him. As the patients admit, against the background of taking the medicine, all these unpleasant symptoms quickly pass.

Satisfied with this drug, parents report in their reviews that the drug quickly leads to normalization of the stool in the child, helping to overcome dyspepsia. This confirms the instructions for use to "Neobutin".Analogs should be selected by a doctor.

People, among other things, like that this drug is quite affordable, as its price ranges from only 150 to 200 rubles per package. True, there are some complaints that it is not always possible to buy at a pharmacy, as it often can be absent.

Among negative reviews, it is reported that sometimes the drug does not help. Experts comment on this situation by the fact that for some serious diseases, such as, for example, an ulcer, it really can not always help, since treatment of such ailments should be treated differently. In general, doctors speak of it as an effective and safe means.

The article is devoted to "Neobutin" instructions for use, reviews and analogues.