"Kandiderm": instructions for use, reviews, analogues
How to use Candiderm cream? Instructions for the use of external means are presented in the materials of this article. Also, it describes reviews about the drug, lists his indications and contraindications.
Description, composition and packaging of medicament
In which packaging is the Candiderm cream produced? Instructions for use of this tool are enclosed in a cardboard box. It also contains a tube of aluminum with a drug substance.
Active components of this drug are clotrimazole, beclomethasone dipropionate and gentamicin sulfate. It also contains auxiliary ingredients in the form of cetomacrogol, sodium dihydrogen phosphate monohydrate, sodium hydrogenphosphate, methylparaben, benzyl alcohol, propylene glycol, petrolatum, propylparaben, liquid paraffin and water.
Ointment "Candiderm" has a uniform texture and white color. This drug does not possess any characteristic odor.
Pharmacological parameters of the local medicine
What is Candiderm cream? Experts say that it is an antifungal, antimicrobial, antiallergic and anti-inflammatory drug with a combined composition.
This active substance of the drug, as beclomethasone, has pronounced antipruritic, anti-allergic, anti-exudative and anti-inflammatory properties. Its mechanism of action is based on a reduction in the accumulation of leukocytes, the release of inflammatory mediators and specific lysosomal enzymes, inhibition of phagocytosis, as well as an obstacle to the formation of puffiness and a decrease in vascular-tissue permeability.
An ingredient such as gentamicin is an antibiotic. It belongs to the aminoglycoside group, and also has a bactericidal effect. One can not help saying that this component can suppress the activity of Klebsiella, Proteus, pseudomonads, enterobacteria, streptococci, Escherichia and Staphylococci.
As for a substance such as clotrimazole, it has antifungal properties. Its mechanism of action is based on a decrease in the synthesis of ergosterol, that is, an integral part of fungal cells.
Pharmacokinetics of
What are the kinetic parameters of Candiderm cream? The instruction for use does not contain any information on this account. Producers explain this fact by the fact that the ointment in question has a combined composition. This greatly complicates the tracking of its pharmacokinetic characteristics.
Cream "Candiderm": indications
This drug is well manifested in the following diseases:
- epidermophytia stop;
- phlebotoderma;
- dermatoses with secondary infection;
- for allergic dermatosis;
- dermatomycosis( including with lesions of the inguinal region);
- dermatitis after insect bites;
- diffuse form of neurodermatitis;
- eczema;
- is red flatly deprived;
- atopic dermatitis;
- anogenital itching.
Contraindications
The external preparation Candiderm, the analogues of which are listed below, is prohibited to be used in the following pathological conditions:
- varicella;
- trophic wounds;
- individual hypersensitivity;
- rosace;
- open wound surfaces;
- post-vaccination reactions on the skin;
- of acne vulgaris;
- viral skin lesions;
- Tuberculosis of the skin;
- syphilitic reactions on the skin.
Candiderm Cream: Instructions for use
The drug should be applied to affected areas of the skin twice a day( after awakening and before going to bed).The duration of such therapy depends on the individual patient's tolerance and overall effectiveness of the treatment process.
After 4 weeks of active cream application, the patient may experience first undesirable effects.
Do you use ointment "Candiderm" in pediatric practice? The doctors' comments say that the age limit for the use of this remedy is the period of life up to 16 years.
If necessary, according to the decision of the attending physician, this medication can be prescribed to children aged 7-16 years.
Side effects of
What side effects does the drug Candiderm( cream) cause? The instruction says that prolonged therapy with this remedy can lead to systemic reactions such as suppression of the adrenal cortex.
With the correct use of the drug, negative effects are extremely rare, and also have a weak and temporary character.
So, against the background of using the drug Candiderm, the following allergic responses may occur in patients:
- striae, contact dermatitis, maceration, urticaria;
- skin dryness, swelling, flaking, hyperemia;
- telangiectasia, furunculosis, hypertrichosis, pyoderma;
- burning sensation, perioral dermatitis, hypopigmentation, folliculitis;
- acne eruptions steroid, sweating, atrophic changes on the skin.
Drug overdose
When applying a large amount of cream on large areas of the skin, the following overdose symptoms may appear in the patient:
- weight gain;
- hypokalemia;
- increased blood pressure;
- glucosuria;
- manifestations of hypercortisy.
With such deviations, the patient is corrected electrolyte balance, as well as post-syndrome therapy.
Special recommendations
It is forbidden to use "Candiderm" ointment in ophthalmic practice. Also, this drug should not be applied to the skin around the eyes.
Occlusive dressings significantly increase the effectiveness of the drug.
When using this medication with bandages, transdermal absorption of its active elements( in particular beclomethasone and gentamicin) may increase. This can cause the emergence of negative systemic reactions.
When the fungal and bacterial resistance is observed, the drug is canceled.
The treatment with aminoglycosides is characterized by the development of cross-resistance.
In pediatric practice, the Candiderm ointment is used only under indications and under medical supervision.
Applying a medication and applying bandages to large areas of the skin can lead to suppression of the pituitary-hypothalamic-adrenal system.
Drug analogues and its cost
How can I replace Candiderm cream? Analogues of this drug are sold in all pharmacies and are released without a medical prescription. The most popular substitutes for this medication are the following: "Belogent", "Betagenot", "Betaderm".
How much does the Candiderm ointment cost? The price of this local remedy is quite high( according to most patients).One tube of an antifungal drug you can buy for 450-470 rubles.
Reviews about the medicine
Doctors assign a unique anti-fungal, antipruritic and anti-inflammatory properties to the cream "Candiderm".They leave only positive reviews about this drug. According to them, the drug in question is fairly well tolerated by patients and in a short time allows to achieve the desired result.
As for patients, they also talk about the high effectiveness of this medication. After several application of the cream, the signs of most skin diseases are significantly reduced.