Symptoms of diffuse pancreatic changes: what is it, the symptoms and treatment
Echogenicity of the parenchyma of a healthy pancreas on ultrasound is similar to the echogenicity of the liver and spleen. In its structure, the gland has a head, body and tail of optimal size. Unfortunately, people are already turning to specialists who already have problems, and on the monitors of diagnostic devices, signs of diffuse pancreatic changes are often observed because of its inflammation or other pathology.
On the diffusion of
The term "diffusion" in Latin means "spreading" or "interaction."From the point of view of physics and chemistry, this is the penetration and interaction of atoms or molecules of one substance with the atoms and molecules of another. Studying the phenomenon of diffusion, scientists began to understand the essence of the processes occurring in the human body better. This is most often the pancreas. Diffuse changes - what is it?
It is easy to observe this phenomenon. It is enough to add a little ink to the glass with water and see how the substances mix. In anatomy, this phenomenon is associated with the interaction and replacement of some cells by others. This is what is found in the ultrasound study: the cells altered by the pathology are located next to the healthy ones. Symptoms of diffuse pancreatic changes are usually local( focal) or mixed( diffuse).
What are the manifestations of diffuse changes in the pancreatic parenchyma?
Pathogenic changes in the gland tissue are most often chronic, and therefore there are no symptoms. But on ultrasound at usual sizes at a gland ehogennost it is raised or increased. In elderly patients suffering from cardiovascular diseases, diabetes mellitus, the death of healthy cells is gradually occurring, they are replaced by connective or adipose tissue.
. Similar transformations are also observed when blood supply to the enzyme-forming organ, liver, violation of the biliary tract, violation of endocrine and metabolic processes. In what other cases are diffuse changes in the liver and pancreas?
Similar symptomatology is observed with pancreatitis or dystrophic metabolic disturbance. The diagnosis of "pancreatitis" may not be confirmed, and then treatment is not prescribed, and the patient does not recognize DIPH.As a rule, the spreading changes occur in the glandular tissue. In chronic disease, pathogenic tissue changes are virtually asymptomatic. These are moderate diffuse changes in the pancreas.
The disease can be triggered for various reasons:
1) Imbalance in nutrition. Abuse of fatty, floury, salty, sweet and savory products.
2) Predisposition on the genetic line.
3) Stress and nervous overexertion.
4) Drug and alcohol addiction.
5) Chronic diseases of the digestive system.
6) Self-medication and unsystematic drug use.
How to treat diffuse pancreatic changes? Consider this below.
Insufficient amounts of insulin in the blood and detection of glucose in the urine are also provoked by DIP.As a rule, the cause of these changes is pancreatitis, which must be treated. It is also necessary to comply with certain rules of the patient's behavior, compliance with the diet.
The main signs of diffuse pancreatic changes
As a rule, the signs of CI are associated with the underlying disease. Most often, patients complain that they feel heavy in the stomach, they suffer frequent diarrhea or, on the contrary, constipation. In acute pancreatitis, the pressure in the pancreatic duct is often increased, which can cause its deformation. Due to the violation of the enzymatic function, some of the digestive enzymes can pass through the pancreatic parenchyma cells and cause poisoning of the body. In this case, the patient experiences pain on the left under the breastbone, nausea, often accompanied by vomiting. There is a rapid pulse and low blood pressure. Such a condition, as a rule, requires hospitalization.
The initial stage of chronic pancreatitis is provoked by the appearance of edema and hemorrhages in the gland tissues. Then comes atrophy, iron decreases in size, there is a proliferation of connective tissue, and enzyme-forming cells cease to produce digestive enzymes. Fibrosis is also accompanied by the displacement of healthy cells of the prostate and replacement of their connective tissue. The production of hormones and enzymes ceases. At the initial stage, the symptoms are meager and often similar to those of the inflammation of the pancreas. There are moderate diffuse changes in the pancreas.
Replacement of normal cells of the body with fatty tissue is called lipomatosis. Symptomatic DIPH with lipomatosis depends on its volume. With insignificant changes in CI, pathology may not manifest itself, but in more serious cases the body begins to gradually experience a deficiency of hormones and enzymes. The proliferation of lipoid tissue leads to compression of the parenchyma and, as a result, to the disruption of pancreatic function and the appearance of pain syndrome. These are diffuse changes of the pancreas according to the type of lipomatosis.
To hollow organs are: stomach, urinary and gallbladder. Organs consisting of parenchyma( glandular tissue): pancreas, spleen, liver, etc. The main function of the parenchyma of the prostate is the production of enzymes and hormones.
In diabetes mellitus, chronic pancreatitis or acute pancreatitis, there are often changes.
On ultrasound, there is an increase in echogenicity of the glandular tissue, this is due to the inflammatory process and when the connective tissue( fibrosis) coarsens, which leads to an increase in density. The cause of this anomaly is an imbalance in the metabolism. Another cause of increased echogenicity is lymphomatosis( replacement of the parenchyma with fat cells).
Puffiness of the gland can occur due to pancreatitis, due to which the density of the parenchyma changes and, as a consequence, the echogenic reaction varies too.
How do diffuse changes in the liver and pancreatic parenchyma affect the organs?
The parenchyma structure can be uniform and fine-grained. Slightly increased granularity is also not a big deviation. Together, the increase in granularity indicates the presence of inflammation and dystrophic changes in the gland associated with malnutrition.
A healthy parenchyma of the pancreas resembles a liver echostructure, the same homogeneous and fine-grained. Age-related changes in the echogenicity of the gland structure indicate an evolving lipomatosis, which is often associated with the onset of diabetes. Symptoms of diffuse pancreatic changes can be very informative.
This is its secondary changes, a response to pathology in neighboring digestive organs, closely related to it. Especially often DI glands arise because of problems with the liver and biliary tract, since it most closely interacts with these organs. In the ultrasound study, the reactive echoes of diffuse pancreatic changes resemble acute pancreatitis, since they are often the secondary consequence.
Fibrotic MI is a scarring in the gland of connective tissue that propagates through tissue cells. The reasons for this process are often:
1) Metabolic disorders.
2) Alcohol poisoning.
3) Viral lesions.
4) Inflammatory processes.
And the damage caused by viruses, concern the entire hepatobiliary system, and not one of the pancreas. On ultrasound, diffuse changes in the pancreas have a high echogenicity and density. The presence of diffusive fibrotic changes may indicate an existing benign tumor of glandular tissue - fibroma, the growth of which can squeeze the gland and cause pain.
Depending on the location of fibroids, different symptoms will be present. For example, when it is in the head of the prostate, the flow of the flow channel is compressed, and a symptom of jaundice appears. If the tumor presses on the duodenum, nausea, vomiting, and other symptoms occur that require differentiation with intestinal obstruction. What are the other echoes of diffuse pancreatic changes?
There is a replacement of healthy glandular cells with fatty tissues, unable to perform the enzymatic function of the pancreas, which leads to hypofunction of the gland. For lipodystrophy, which occupies less than half the volume of the entire gland, mixed medication is used in conjunction with the diet. If the lesion covers more than half the organ and its work is broken, surgery is indicated. Diffuse changes in the parenchyma of the liver and pancreas in some cases are life-threatening.
Three distinct elements are distinguished in the structure of this secretory organ: body, head and tail, having a pear-shaped form and adjacent to the spleen. Normally its width is 2-3 cm. Through the entire gland an excretory duct about 15 cm long passes. Blockage of the hepatic vein can lead to the DI of the tail of the prostate, the symptoms of this are that this part is condensed.
Approximately one-fourth of all pancreatic diseases are associated with diffuse tail changes. In case of minor injuries, the tail is treated conservatively. In the case of deep lesions, removal of the tail is indicated, followed by closure of the blood vessels.
How do diffuse changes in the liver and pancreas come about?
Determined by DIPA using ultrasound. Ultrasound reveals that the density and structure of the tissue changes, and the foci of inflammation are determined.
But it's not enough to make a diagnosis. To confirm the DI, a biochemical blood test, endoscopy of the gland is performed. It is very important to correctly collect anamnesis in the patient( a survey about the presence of complaints), as well as to conduct additional instrumental studies and palpation.
The general picture is supplemented by a general analysis of blood, urine, endoscopy of the gastrointestinal tract, coprogram, etc. Pancreatic enzymes and glucose in the blood, as well as an inhibitor with respect to trypsin play an important role.
With the help of ultrasound, the size of the gland and its ducts is determined, neoplasms and seals are detected. To clarify the diagnosis, the following are shown: computed tomography and ERCP, allowing more accurate identification of the causes of changes in the tissues of the enzyme-forming organ. Most clearly manifested diffuse changes in the pancreas according to the type of lipomatosis.
The development of MI in the pancreas, liver and other organs can be slowed down. Here are some rules:
1) It is necessary to completely abandon alcohol.
2) Observe the diet, eat in small portions, but often.
3) Minimize the consumption of fatty foods.
4) Discard the canned products.
5) Eat freshly squeezed juices and drink herbal teas.
Do not give up if you are diagnosed with DIP.It is just worthwhile to undergo the necessary research and in the future carefully listen to your body, monitor the health of such important organs as the liver and pancreas. Diffuse changes, what it is and what are the methods of treatment, we considered in the article.