"Avodart": the instruction, responses."Avodart"( tablets): the price

What do you know about Avodart? Analogues, price, indications and instructions of this tool will be presented in this article. Also you will learn about what properties are inherent in this medicine, what pharmacological group it belongs to, what it is, etc.

Form, description, packaging and composition

The drug "Avodart" is available in the form of soft gelatinous oblong and opaquecapsules of yellow color, marked with the code "GX CE2".On sale this medication can be found in cardboard boxes, where blisters are placed with 90 or 30 tablets.

Dutasteride acts as an active element of the agent under consideration, and gelatine, butylhydroxytoluene, triglycerides, titanium dioxide, red ink for printing, mono-diglycerides of caprylic acid, glycerin, lecithin and ferric oxide are used as additional constituents.

Pharmacodynamic characteristics of

Which pharmacological group is Avodart? Instruction for use says that this antiandrogenic remedy. Its active substance is a double inhibitor of the enzyme 5-alpha-reductase. This component is able to inhibit the conversion of testosterone to DHT.This is due to the suppression of the activity of 5-alpha-reductase of the first and second types.

After taking Avodart, urination normalizes, the prostate gland size decreases, and the likelihood of curing the disease without surgery is increased.

Features of the drug

According to specialists, Avodart tablets show a therapeutic effect in 8-15 days after the start of treatment. The higher the dose of this drug, the more it affects the production of DHT.

Pharmacokinetic properties of

The drug "Avodart", the price of which is indicated below, is found in the blood in the maximum concentration 1.5 hours after ingestion. Its bioavailability is 60%.Simultaneous food intake has no effect on the kinetic parameters of the drug.

This agent has a rather high degree of connection with plasma proteins( about 99%).It should also be noted that with a systematic and long-term intake of about 12% of the active ingredient enters the sperm.

How is the tool treated? What do the instructions and testimonials say about this?"Avodart" is extensively metabolized in the human body. Approximately 2-15% of the active substance is excreted unchanged through the intestine. Complete removal of the drug is carried out about a month after the end of the course of therapy.

Specialists say that even after six months, a small amount of medicine can be found in the blood.

Indications

What is the purpose of this drug? What do the instructions and testimonials say about this?"Avodart" is a medicinal product used in the following cases:

• with monotherapy and prophylaxis of prostatic hyperplasia progression of the prostate( benign form) by reducing its size, improving urination, alleviating symptoms, and reducing the likelihood of surgery and the risk of acute urinary retention;
• with combined therapy with alpha1-adrenoblockers, as well as to prevent the progression of prostatic hyperplasia of the prostate( benign form) by reducing its size, improving urination, alleviating symptoms, reducing the likelihood of surgery and the risk of acute urinary retention.

Contraindications

Do not use Avodart with:

• hypersensitivity to dutasteride, as well as other drugs;
• hypersensitivity to inhibitors of 5-alpha-reductase.

It should also be noted that this medication is contraindicated for admission to children and women.

With caution Avodart should be prescribed for liver failure.

Avodart Capsules: Instructions for Use

Medication is taken orally regardless of food intake.

Capsules are swallowed whole, without chewing and not opening( the contents can cause irritation of the mucous oropharynx).

In adults and elderly men with BPH, the medicine is prescribed in the amount of 1 capsule once a day.

Despite the fact that the therapeutic effect of taking this drug comes after two weeks, it is recommended to take at least six months.

For the treatment of the mentioned disease, Avodart can be used both in monotherapy and in combination with alpha 1-adrenoblockers.

Special medication

At a dose of 500 μg per day, about 0.1% of the drug is secreted by the kidneys. In this regard, there is no need to reduce dosage in people with disrupted urinary system.

Patients with impaired liver function Avodart should be taken with extreme caution, since its active substance undergoes intensive metabolism in this organ.

Side effects of

What side effects occur when taking this drug? What do doctors say about this? Avodart can cause the following undesirable reactions:

• apathy and depression;
• itching rashes on the skin, hives, swelling, allergic manifestations( up to the angioedema);
• hair loss on the body surface and hypertrichosis;
• pain and testicular edema;
• decreased libido and sexual desire, erectile dysfunction, swelling and painful sensations of the mammary glands, problems with ejaculation.

The likelihood of adverse reactions is significantly reduced with increasing duration of therapy( eg, from the second year of taking capsules).

If you combine Avodart with other medications, the frequency of occurrence, as well as the types of adverse events, may differ slightly.

Specific recommendations for

Avodart capsules can not be opened, and contact of their contents with mucous membranes and skin can be tolerated. If the drug is still on the skin, it should be washed off immediately with running water.

The combination of dutasteride and alpha-blockers increases the risk of heart disease.

Before taking the medication, as well as during the therapy, it is necessary to carry out the examination of the prostate gland( rectal finger, PSA, etc.).

Cost of capsules and similar tools

How much does the drug "Avodart" cost? The price of this medicine is very high. You can buy 30 capsules of this medication for 1500-1600 rubles.

The most common analogues of Avodart are such products as Proscar, Adenosterid, Finpros, Urofin, Prostan, Penester, Finistere.

One can not help saying that the cost of these drugs can be slightly higher than the capsules we are considering.

Reviews

Avodart is a fairly popular drug that is used to treat and prevent BPH.Reviews about it can be found very different. Some patients report that after 12 months of use of the medication the prostate gland has significantly decreased. However, with the cessation of treatment, it again increased. Other patients are extremely unhappy with the high cost of this medication, as well as erectile dysfunction and a decrease in sexual desire on the background of its intake.

Specialists claim that such reactions of the body disappear on their own after 3-4 months of treatment.