Analogues of "Moxifloxacin", their comparison and reviews
In cases of occurrence of any inflammatory processes in the body, doctors usually prescribe the use of antibiotics in the form of tablets or injections. If the same problems with the eyes( conjunctivitis, keratitis, dacryocystitis, etc.), then such remedies are applied in the form of drops.
"Moxifloxacin" and its analogues are popular in this sphere.
"Moxifloxacin": formulation, composition
The drug is available in three forms:
- Eye drops( "Moxifloxacin").The composition includes moxifloxacin hydrochloride, as well as sodium chloride, sodium hydroxide, hydrochloric acid, boric acid, water.
- Solution for injection( "Moxifloxacin").It is intended for intravenous administration and can be used alone or in combination with other solutions( xylitol, glucose, sodium chloride, etc.).
- Tablets( "Moxifloxacin-Pharmex").The pills covered with a cover."Moxifloxacin"( tablets) is prescribed in the presence of inflammatory processes, including during pneumonia, bronchitis, etc.
The antibiotic is distinguished by its excellent absorption in all tissues of the body and shows high effectiveness of the action.
The main part of the preparation is withdrawn together with feces, only a small part of it passes through the kidneys. Therefore, it is allowed for the treatment of patients with kidney pathologies, since individual dosage adjustment will not be necessary.
Indications for the use of "Moxifloxacin", the price of the drug
"Moxifloxacin"( drops) are used in the following situations:
- for the prevention and treatment of eye diseases: barley, conjunctivitis, meibomite, keratitis, blepharitis, corneal ulcer, etc.;
- for the treatment of infectious eye pathologies that have occurred as a result of surgery or trauma;
- before surgery and during the postoperative period in ophthalmology.
Injections and tablets "Moxifloxacin" are used to treat:
- infectious diseases of the respiratory tract;
- of pelvic inflammatory disease;
- infectious skin diseases;
- bacterial infections that were caused by bacteria that are sensitive to the use of the drug.
Many patients are interested in what is the cost of the drug "Moxifloxacin".The price is in the range of 759-850 rubles and depends on the pharmacy and the region of residence.
Contraindications and side effects of
What are the contraindications to use and side effects of the drug "Moxifloxacin"?The instruction for use says the following.
The use of the drug for the treatment of children under 18 years of age is prohibited.
In addition, "Moxifloxacin" is not used during pregnancy, during lactation, as well as in the presence of individual intolerance of the components of the drug.
Side effects of
The drug has excellent tolerability and minimal side effects, which are very rare. In ophthalmology, they can manifest themselves in the form of dry eyes, allergic reactions, discomfort and burning during eye rotation, loss of visual acuity, eye irritation, lacrimation, keratitis, diplopia.
The use of tablets and injections can provoke the appearance of abnormalities in the activity of the gastrointestinal tract, and can also cause dizziness, insomnia, seizures, increased pressure, chest pain, back pain, vaginitis, pruritus, urticaria, etc.
All side effects occur mainly with an overdose of "Moxifloxacin".In this case, you must immediately stop taking the drug and go to the clinic to prescribe local treatment, based on the symptoms.
Interaction with other medications and special instructions
Before using moxifloxacin-based products, it is important to alert your doctor about the possible use of other medications. It does not combine with the means, which include aluminum, zinc, sucralfates and metal cations. In such situations, it is important to strictly adhere to the intervals of application: "Moxifloxacin" can be taken 4 hours before the time of taking the funds with the above components, or at least 8 hours after their intake.
Those taking the medicine in the form of eye drops should follow certain precautions:
- is not advisable to be in the open sun;
- is not worth doing work that requires concentration;
- should not be used to treat children and use caution to older people.
How to use the drug "Moxifloxacin"
Eye drops should be instilled in each eye 1 drop 3 times a day. Treatment can last up to 5 days.
After opening the vial, the drug is allowed to be stored for no more than 30 days at a temperature of up to 30 degrees.
As you can see, if you need to select effective drops for the treatment of eye diseases, one of the best options will be Moxifloxacin. The price of the drug also contributes to this, since it is significantly lower in comparison with other agents with a similar effect.
Tablets and injections are administered no more than once a day, with a dose of 400 mg.
What does the analogue differ from the original drug?"Moxifloxacin" has a broader spectrum of action due to a greater amount of active substance in the formulation.
Consider, as examples, the most famous drugs that are substitutes for "Moxifloxacin": "Levofloxacin," "Avelox," "Vigamox," "Moxifur."
The first analog preparation that we will consider will be "Levofloxacin 500".The price of the product is in the range of 134 rubles.
"Levofloxacin" can be produced in the form of tablets, solution for infusions or eye drops. The difference is only in the spectrum of application of drugs.
Drops are prescribed for the treatment of anterior eye infections that have been caused by micro-organisms susceptible to levofloxacin.
Tablets and solution may be prescribed for treatment of:
- acute sinusitis;
- exacerbations of chronic bronchitis;
- of bacterial prostatitis;
- of drug-resistant forms of tuberculosis;
- of urinary tract infections.
The use of drops of "Levofloxacin" is contraindicated in children under 12 months of age, as well as pregnant women, mothers during lactation and people with individual intolerance or hypersensitivity to the components of the drug. The solution and tablets have the same limitations, with the difference that they are allowed only from the age of 18 years.
Treatment with drops is carried out according to the following scheme:
- for the first two days instill the drug every 2 hours( only 8 times per day);
- from the third to the seventh day instill the drug every 4 hours( only 4 times a day).
The total duration of therapy can be from 5 to 7 days.
Side effects during the application of drops are not very common and can occur in the form of redness of the eyes, burning, decreased visual acuity, the appearance of mucus or dry eye syndrome, allergic reactions, headaches, contact dermatitis.
Tablets and solution for infusion have the same side effects as "Moxifloxacin", so do not repeat.
The main pluses of drops "Levofloxacin 500": the price of the drug, high efficiency, minimum contraindications to use and side effects.
The country-manufacturer of the drug "Avelox" - Germany( Bayer).The product is available in the form of tablets or a solution for infusions.
The main active substance of the drug is moxifloxacin, therefore it is prescribed when:
- the presence of bacterial infections that were provoked by microflora-sensitive moxifloxacin;
- infectious diseases of the respiratory tract, including pneumonia, chronic bronchitis, acute sinusitis;
- infections of soft tissues and skin;
- inflammatory diseases of the pelvic organs.
As you can see, "Avelox", the price of which is within 758 rubles, has a wide range of bactericidal effects.
The drug should be taken once a day, with a dose of 400 mg.
You can not chew the tablets, they just need to drink enough ordinary water( at least half a glass).
The duration of treatment will depend on the disease itself. For example, with exacerbation of chronic bronchitis, therapy will last 5 days, with non-hospital pneumonia - 10 days, acute sinusitis or uncomplicated infections of the skin - 7 days, pelvic inflammatory diseases - 14 days and so on.
"Avelox" can be used both as an independent agent, and in combination with other medicines to increase the effectiveness of therapy.
Cases of drug overdose have not been detected, and the likelihood of side effects is minimized. If they happen, they are expressed mainly in the form of violations of the functionality of the gastrointestinal tract: nausea, vomiting, diarrhea, abdominal pain, taste disturbance.
Even more rarely occur the following side effects:
- increased heart rate, chest pain, increased blood pressure;
- sleep disorders, feelings of unreasonable anxiety, depression, weakness, dizziness;
- pain in the back, joints, muscles, tendons;
- allergic reactions( urticaria, pruritus, rash);
- decreased visual acuity.
It is extremely rare, taking analogues of "Moxifloxacin" in the form of tablets( in this case - "Avelox"), it can provoke the appearance of: shortness of breath, convulsive attacks, coordination disorders.bronchospasm, etc.
The use of "Avelox" is contraindicated:
- with hypersensitivity to the components of the drug;
- for children under 18 years of age;
- during pregnancy and lactation;
- patients with epilepsy.
Store tablets and Avelox solution at temperatures below 25 degrees Celsius.
Absolutely any medicine has analogues."Moxifloxacin" in this regard was no exception. About its substitutes in the form of a solution and tablets, we talked, so now let us consider an analogue in the form of eye drops - "Vigamox."
The drug is used to treat conjunctivitis, keratitis, corneal ulcers, meibomita, blepharitis, dacryocystitis and barley. In addition, the agent can be used for the prevention and treatment of bacterial inflammation of the eye that occurs as a result of surgery or trauma.
How to use Vigamox drops correctly? Instruction for use says that the drug must be digested three times a day for 1 drop. Treatment should be carried out until the time of full recovery.
Contraindicated use of the drug in the presence of hypersensitivity to its components and during breastfeeding. For children, the elderly and pregnant women, the use of "Vigamox" drops is allowed only on the prescription of the doctor and with the adjustment of the maximum daily dose of the drug.
No cases of drug overdose have been detected, but there may be some side effects after application:
- allergic reactions;
- burning or tingling;
- fear of light;
- blurring of vision;
- lacrimation or dry eyes.
Less common are headaches, vascular edema( including laryngeal edema, pharynx, face), respiratory failure.
Drops can cause temporary visual impairment, so it is worth to abandon the management of vehicles until it is fully restored.
The price of the drug is in the range of 350 rubles per bottle.
Another drop of eyes based on moxifloxacin - "Moxifur".The price for the facility is about the same as in the previous version and may vary, depending on the pharmacy and the region of residence.
Moxifur drops are absolutely similar to Vigamoks: indications for prescription, contraindications, method of administration and possible side effects in both drugs are the same due to identical composition and mode of action.
Therefore, we will not repeat the same thing and turn to the feedback of patients about the drugs based on moxifloxacin.
Reviews of "Moxifloxacin" and its analogues
What do those who used to treat the original drug and its analogs say?"Moxifloxacin" helped to solve the problem and accelerate recovery, or after its application the patient's condition only worsened? Consider the answers to these questions in the form of feedback on specific means.
Reviews about the drugs "Moxifloxacin" and "Levofloxacin"
Inexpensive and very effective drugs for fighting infectious and inflammatory diseases are the main essence of all the reviews about these two drugs. Most often they were used for bronchitis, gynecological infections, sinusitis and sinusitis. In each of these cases, the drugs helped to quickly get rid of the symptoms of diseases and contributed to an early recovery.
Cons are the presence of side effects: pain in the muscles and joints, a feeling of constant weakness, confusion.
Although, ultimately, the presence of positive dynamics in the fight against the disease contributed to the fact that the withdrawal of drugs was not required and the treatment was successful.
Reviews about the "Avelox"
The price of the remedy is practically its only negative, as it is much higher, in comparison with other analogues of "Moxifloxacin".There are also cases of side effects in the form of nausea or dizziness, which become less tangible or completely disappear after eating, or if you eat something before taking an antibiotic.
However, high effectiveness of the drug in the treatment of pneumonia, bronchitis, inflammatory processes, etc. is noted.
Reviews about the "Vigamox" and "Moxifour"
Those who used the drops "Vigamox" or "Moxifur", note their high efficiency and speed of action. Many people notice a positive result already on the second-third day after the beginning of the use of drugs.
Another undoubted advantage is the availability of eye drops based on moxifloxacin, because the price is calculated for the average buyer.
But there are situations when the use of either of these two agents caused side effects in the form of dryness and itching in the eye area, so patients had to select another remedy.