"Ganaton": what helps, how to take? Reviews about "Ganaton"

What is a drug such as "Ganaton"?What helps this tool? The answer to these questions is found in this article. Also, you will learn about the opinions of patients about this medicine, whether it has contraindications, and how it should be properly taken. ganaton from what helps

Form of medicament, its packaging, composition, description

In what form are the preparations manufactured by "Ganaton"?The instruction, reviews state that such a preparation can be purchased in the form of tablets that have white color, a sheath( film), a round shape, an engraving "HC 803" on one side and a risk on the other.

The active ingredient of the medicament in question is isotypride hydrochloride. As an auxiliary constituent, this medicine includes lactose, carmellose, corn starch, silicic acid anhydride, macrogol 6000, magnesium stearate, titanium dioxide, hypromellose and carnauba wax.

In the sale of such tablets come in blisters, which, in turn, are packaged in packs of cardboard.

Principle of the drug

What is "Ganaton"?What helps with this drug? It is used to improve motor and tone of the gastrointestinal tract.

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As the active ingredient of this agent is the titopride hydrochloride. This substance specifically affects the upper pathways of the digestive system, and also speeds up the removal of food from the stomach. It should also be noted that the component under consideration is capable of exerting an antiemetic effect.

Properties of the drug

What is remarkable about such a tool as "Ganaton"?What helps it, we will tell further.

This medication is a stimulant for the release of acetylcholine. Its main substance activates the gastric motility( propulsive).This is due to antagonism with dopamine D2 receptors, as well as a dose-dependent inhibition of acetylcholinesterase activity. ganaton instructions reviews

Itopride hydrochloride activates the release of acetylcholine, and also inhibits its destruction.

Kinetic features of the drug

Where is the absorption of such a drug as "Ganaton"?Instructions for use, reviews argue that the active ingredient of this drug is very quickly and almost completely absorbed from the intestine. Its relative bioavailability is about 60%.This is due to the metabolism of the drug, which occurs when first passing through the liver. The intake of food has no effect on the bioavailability of the agent.

After oral administration of 50 mg of tacispride hydrochloride, its peak concentration is reached after 0.5-0.75 hours and is about 0.28 μg / ml. Repeated administration of the drug at a dosage of 50-200 mg three times a day for a week causes a linear pharmacokinetics. In this case, the cumulation is minimal.

The association of the drug with plasma proteins is approximately 96%.It is actively distributed in all tissues, and also in high concentrations found in the liver, kidneys, adrenals, small intestine and stomach. The medication penetrates through the BBB in small quantities. It is also excreted in mother's milk.

The excretion of tacopride hydrochloride and its derivatives occurs together with urine. Renal excretion of the active substance after a single dose at therapeutic doses is about 75%.The final half-life of this remedy is approximately six hours. The drug "Ganaton": what helps?

This agent is actively used in the treatment of gastrointestinal problems, which are associated with non-ulcerative functional dyspepsia( including chronic gastritis), as well as slowed down gastric motility. does the ganaton help with Helicobacter?

So, when should you use the medicine "Ganaton"?The use of this agent is indicated with:

  • anorexia;
  • bloating;
  • heartburn;
  • vomit;
  • feeling of overflow in the stomach after a meal;
  • pain or discomfort in the epigastric region;
  • nausea.

Prohibitions for taking medication

Now you know what is remarkable about such a tool as "Ganaton".What this drug treats, we also found out. It should be specially noted that the medication in question is contraindicated in the case of:

  • pregnancy;
  • gastrointestinal bleeding, mechanical obstruction or perforation of the gastrointestinal tract;
  • under the age of 16;
  • breastfeeding;
  • hypersensitivity to taperpride or other accessory drug ingredient.

Cautious use of the drug

This drug is cautiously prescribed to elderly people due to frequent decreases in kidney and liver function, as well as the presence of concomitant diseases or other treatment.

Due to the increased effect of acetylcholine, the medication in question is recommended with extreme caution to patients in whom development of cholinergic side effects can aggravate the course of the underlying disease. ganaton application instructions reviews

How to take "Ganaton"?

The tablets to be taken should be taken orally before meals. They are washed down with plain water.

The drug has no effect on a person's ability to drive vehicles, as well as complex mechanisms. When using Ganaton, elderly people or people with impaired renal and hepatic function, they require constant medical supervision.

Sometimes a doctor can correct the recommended dosage. If you accidentally swallow a large amount of the drug requires the implementation of such standard measures as symptomatic treatment and gastric lavage.

In what dosage should the patient use the "Ganaton" medication? The application( drug reviews reviewed below) should only be done after consultation with the doctor. The daily dosage of the drug in question for adults is 150 mg. If necessary, the specified amount can be changed by a specialist.

Typically, this drug is recommended to take three times a day, one tablet before meals( 50 mg).The duration of treatment is determined by the doctor and can be approximately 5-8 weeks.

Side effects

What side reactions can the "Ganaton" medication cause? This remedy helps a lot of diseases of the digestive system, but it can provoke the appearance of the following undesirable effects:

  • Endocrine system: gynecomastia, increased prolactin level.
  • Hematopoiesis system: thrombocytopenia, leukopenia.
  • Allergic reactions: skin itching, flushing on the skin, anaphylaxis, rash.
  • CNS: headaches, dizziness, tremor.
  • Digestive tract: jaundice, diarrhea, increased salivation, constipation, nausea, abdominal pain.
  • Changes in laboratory tests: increased levels of bilirubin and alkaline phosphatase, as well as ALT, AST and GGT.

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Drug interactions

Metabolic interaction with this drug is not possible. This is due to the fact that it is metabolized not under the influence of isoenzymes of the cytochrome P450 system but under the action of flavin monooxygenase.

The active substance of the drug in question enhances gastric motility, which can affect the absorption of other concurrently used drugs. Caution should be observed when taking medications with a low therapeutic index. The same applies to preparations with enteric-coated membranes and sustained release of the main component.

When combining "Ganaton" with "Diazepam", "Warfarin", ticlopidine hydrochloride, sodium diclofenac, nicardipine hydrochloride and "Nifedipine", there was no change in the binding of tautopride to plasma proteins.

Such anti-ulcer drugs as "Ranitidine", "Cimetidine", "Cetraxate" and "Teprenone" do not affect the kinetic features of the taredrop.

Anticholinergic medications weaken the effect of the active substance of the agent in question.

Feeding and gestation period

At present, there is no sufficient data on the use of taupride hydrochloride during pregnancy. The use of this tool in the process of bearing a fetus is possible only in the absence of alternative therapy, as well as with potential benefits for the mother, which exceeds the risk for the fetus.

It should also be noted that against the background of the use of this drug there is a risk of side effects in the infant. In this regard, if you need to use the medication during breastfeeding, lactation should be discontinued. how to take ganaton

Similar drugs and the cost of the drug

Do you know about how much is the medication under consideration? If you do not possess such information, then we will provide it to you. The price of this product depends on the extra charge by the first aid kit of the network and is approximately 250 rubles for 10 tablets.

If the drug with this name was not found, then it can be replaced by an analog. To such medicines means with the same active substance, i.e. with itopride. They are often used by them "Itomed", "Itopride", "Itopru" and "Primer".

Reviews of patients and specialists

Does "Ganaton" help with Helicobacter pylori? Specialists report that the agent under consideration is a preparation that improves the tone and motility of the digestive system. It is not an antibacterial medicine that can overcome the bacterium mentioned above. However, in some cases, it is still prescribed in this disease, but only in complex therapy together with antibiotics and other antiulcer drugs.

Almost all patients who have ever taken the drug in question are talking about its high effectiveness. According to their opinion, after the passed course of therapy of this drug completely eliminates the feeling of nausea and discomfort in the epigastric region, as well as the severity and pain in the stomach.

Some patients respond well about this drug as a preparation for episodic elimination of heartburn and vomiting.

As for reports of adverse reactions of the "Ghanaaton", they are single. As a rule, against the background of taking this drug in some patients there is increased salivation, drowsiness or dizziness. ganaton from what heals

There have been no reports of cases of overdose by this agent to date. The price of such a drug as "Ganaton" is perceived by consumers as acceptable or high.