"Clotrimazole"( ointment): what helps, composition and reviews
What is a remedy like "Clotrimazole"( ointment)?What is it used for, and how should it be used? This is what we will discuss in this article.
Form, description, composition
Ointment "Clotrimazole" - what helps? Before answering this simple question, it is necessary to tell what the drug is. As is known, it is intended for dermal application. A homogeneous 1% ointment has a white or slightly creamy color, and also contains an active substance such as clotrimazole.
In addition to the main component, this formulation also contains auxiliary ingredients in the form of polyethylene oxide 1500, propylene glycol, nipagine( methyl parahydroxybenzoate), polyethylene oxide 400 and methylparaben.
In what package is the Clotrimazole Ointment sold( what helps this remedy, you can find out from the enclosed instructions)?According to consumers, this product can be purchased in 30 g aluminum tubes, which are placed in packs of cardboard.
Pharmacological characteristics of
What is remarkable about the drug "Clotrimazole"( ointment)?What helps with this drug? Experts argue that this drug is an antifungal medication for topical use, with a wide range of effects.
Why is the antimycotic property of this drug due? This effect is associated with an active component of an ointment, an imidazole derivative.
After the application of local medication, there is a disruption of the synthesis of ergosterol, which is part of most cell membranes of fungi. Such a process changes their permeability, and then causes lysis of the cell.
How does the drug Klotrimazol( ointment) work? What helps this medication? In high concentrations, the drug acts fungicidal, and in small - fungistatically.
It should also be noted that this drug has an effect not only on proliferating cells. According to experts, in fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes. As a result, there is an increase in the concentration of hydrogen peroxide, which reaches a toxic level. This process contributes to the death of fungal cells.
With respect to which mushrooms is the most effective drug "Clotrimazole"?What helps with this medicine? According to the instructions, it works well against dermatophytes, pathogens of colored lichen, molds and yeast-like fungi, as well as the causative agent of erythrasma. It should also be noted that this drug exhibits high antimicrobial activity against staphylococcus, streptococcus, gram-negative bacteria and Trichomonas vaginalis.
Now do you know what "Clotrimazole"( ointment) is? What helps this medicine, we also told above.
What are the kinetic properties of this drug? Experts argue that its active component is poorly absorbed through the skin and mucous membranes, and also has almost no systemic effects.
According to the instructions, the concentration of this agent in the deep layers of the epidermis is much higher than that required to suppress dermatophytes. It should also be noted that when applied externally, the concentration of the drug substance in the epidermis is much higher than the concentration in the subcutaneous tissue and dermis.
The drug "Clotrimazole"( ointment): what helps?
Indications for use in this tool is a huge number. Experts argue that the drug in question is effective with:
- pityriasis, erythrasis and superficial candidiasis caused by dermatophytes, as well as mold, yeast and other pathogens and fungi that are sensitive to the active substance of the drug;
- mycosis stop and skin folds, as well as fungal skin damage;
- mycosis, which is complicated by secondary pyoderma.
Prohibitions on the use of
Does the contra-indication "Clotrimazole" have a contraindication? From what it helps( the price of the remedy is indicated further) this medication, we described above. As for prohibitions to its use, the following are referred to them:
- the first trimester of pregnancy;
- hypersensitivity to the elements of the drug.
With special care, the drug in question is recommended for use during the breastfeeding period.
Ointment and cream "Clotrimazole": instruction
This medication is intended only for dermal application. Ointment "Clotrimazole" should be applied a thin layer on dry and pre-cleaned affected areas two or three times a day. For greater effectiveness, the drug should be gently rubbed with soft and massaging movements. Before applying the medication, it is advisable to wash the affected skin with soap with a neutral pH.
The duration of therapy with this remedy depends on the severity of the disease, as well as the effectiveness of treatment and the localization of pathological changes.
Dermatomycoses are treated with "Clotrimazole" ointment for at least 4 weeks, and otrepidus lichen - 7-22 days.
For fungal lesions of the skin of the legs, it is advisable to continue therapy for 2 weeks after the elimination of the main signs of the disease.
Side effects of
In some cases, with the local preparation "Clotrimazole", the patients experience the following side effects: pruritus, tingling in the areas of application, burning, blisters, erythema, swelling, flaking and skin irritation. It is also possible to have an allergy in the form of urticaria.
Symptoms of overdose and drug interaction
According to experts, the use of the drug in question in large quantities does not cause any conditions and reactions that are dangerous for the life of the patient.
As for the interaction of this remedy, when combined with Amphotericin B, natamycin and nystatin, its effectiveness is significantly reduced.
When using ointments with other agents, no significant adverse interactions should be expected. This is due to the fact that the resorption capacity of the drug in question is very low.
Pregnancy and baby feeding
As mentioned above, the use of this medication is contraindicated in the first trimester of pregnancy. It should be noted that in the course of experimental and clinical studies it has not been established that the use of the ointment under consideration during the period of gestation or during breastfeeding by the baby in any way has a negative effect on the health of a woman or a child. However, only an experienced specialist should decide whether to use this remedy.
The application of this medication directly to the mammary gland is contraindicated.
What do I need to know about the effects of a drug such as Clotrimazole? Ointment - helps with thrush or not? The instruction says that this remedy is effective against the fungi of the genus Candida. Therefore, it is not forbidden to use it against thrush. However, before this, you should consult a doctor.
It is highly not recommended to apply the drug to the skin in the eye area. In the treatment of onychomycosis, it is advisable to ensure that the processed nails are short-cut or have an uneven / rough surface, so that the active substance penetrates better into the affected areas.
People with liver failure need to periodically monitor the liver and its work.
If irritation or symptoms of hypersensitivity occur, treatment with ointment is stopped. If there is no therapeutic effect within 4 weeks, it is necessary to confirm the diagnosis.
The majority of consumers who use the drug Klotrimazol, speak of it exclusively on the positive side. According to their opinion, this drug helped them get rid of fungal skin and nail lesions, and did not cause any adverse reactions. Also, many patients are pleased with the affordable price of this product. It is about 50-80 rubles.