The drug "Soustagard arthro"( ampoules): instruction, reviews and composition

"Sustagard Artro" is a medicinal product that stimulates the process of regeneration of cartilaginous tissues. This medicine has an anti-inflammatory and analgesic effect on the body. Instructions and feedback will be provided to ampoules "Sustagard Arthro" below.

Form of preparation and its composition

The drug is issued in the form of ampoules. Each of them contains sulfate of glucosamine, which acts as an active substance, as well as sodium chloride. As additional components, sodium disulfite, lidocaine hydrochloride, as well as hydrochloric acid of high concentration and water for injection are included in the preparation.

This is indicated by the instruction attached to the "Sustagard Artro".Prices will be considered later.

Pharmacological properties of the drug

The drug works as a stimulant of regeneration, and also performs anti-catabolic, anti-inflammatory, chondroprotective, analgesic and anabolic effects on the body.

The active substance of this medical product, which is glucosamine sulfate, is contained in the human body and serves as a salt."Sustagard Artro" activates the production of proteoglycans by chondrocytes and synovial fluid, thus inhibiting enzymes that lead to the destruction of cartilaginous tissues. In addition, the drug counteracts the formation of superoxide radicals, reducing the activity of lysosomal enzymes and ensuring a normal process of calcium deposition in bone tissues. This stimulates the process of sulfur production during the synthesis of chondroitinsulfuric acid, while avoiding the damaging effects of corticosteroids. There is also a normalization of glycosaminoglycan production, which is disrupted due to non-steroidal anti-inflammatory drugs.

Sulfo groups participate in metabolic processes of cartilaginous tissues and in the formation of glycosaminoglycans. Elements such as sulfoesters are capable of retaining water, ensuring the preservation of cartilage elasticity. This confirms the instruction for the use of the drug "Sustagard Arthro".Price is of interest to many.

In osteoarthrosis, glucosamine sulphate reduces the incidence and severity of the symptoms of this disease, preventing the destruction of cartilage. Weakening of clinical symptoms is usually observed a couple of weeks after the start of the course. The improvement can be maintained for two months after the completion of the drug.

Glucosamine sulphate is characterized by rapid passage through biological obstructions with subsequent penetration into the tissue structure, especially into areas of articular cartilage. The withdrawal period is approximately sixty hours.

According to reviews to ampoules "Sustagard Artro", the instruction is available in each package.

Indications for the use of

This medication should be used for such ailments as:

• Patella chondromalacia.
• Spondylarthrosis.
• Primary or secondary osteoarthritis.
• Presence of osteochondrosis.
• Spondylosis and humeroscapular periarthritis.

Contraindications to the use of

According to the instructions for use with the drug "Sustagard Artro", the list of contraindications for the use of the drug is quite extensive. Therefore, it should not be used under the following restrictions:

• The presence of phenylketonuria.
• Age is up to twelve years.
• Sensitivity to any of the components of the drug.
• The presence of acute heart failure along with impaired conductivity.
• Pregnancy period.
• Pathology of hepatic or renal function.
• Probability of epileptiform seizures.

Also with the "Sustagard" remedy, the instruction for use informs that with special caution the drug should be treated with such conditions as:

• Arterial hypotension.
• Pathology of blood circulation.
• The patient's tendency to malignant hyperthermia.
• Diseases of the respiratory system.
• Epilepsy and the elderly.

In the event that the patient has a tendency to intolerance of various seafood, then during treatment with the drug there is a risk of allergic reactions of the body.

This is confirmed to the ampoules "Sustagard Artro" instruction and feedback.

Dosage and method of application of the drug

The solution of the drug "Sustagard Arthro" is intended exclusively for intramuscular administration. The intravenous way of infusion of the drug is strictly contraindicated.

To prepare the medicine, mix the contents of the ampoule "A" with the solvent "B", this is done in one syringe before the injection procedure. The final solution is administered three times a week in a volume of three milliliters per day. The course of treatment is usually from four to six weeks.

Powder "Sustagard Arthro" instruction manual is also very detailed.

Side effects from the preparation

Within the application of the drug, the appearance of such undesirable effects as various allergic reactions, for example, pruritus and urticaria. In addition, flatulence, constipation and diarrhea are not excluded. Against the background of using the injectable solution, the following reactions are also likely due to the influence of lidocaine:

• Cardiac conduction disturbance.
• Appearance of dizziness, diplopia, pain, numbness of the oral mucosa and tongue. In addition, from the nervous system side, disorientation can occur along with tremor, drowsiness and euphoria.
• Anaphylactic shock may occur as a result of allergic reactions. Sometimes there are swelling.
• Appearance of nausea and vomiting.
• There may be a slight burning sensation with an anesthetic effect, which usually lasts for one minute. Thrombophlebitis is also not excluded.

Sodium disulfite contained in the solution in rare situations can provoke the appearance of bronchospasm as well as severe reactions associated with hypersensitivity.

What else does the instructions for use tell me to ampoules "Sustagard Artro"?

Overdose with

Cases of drug overdose have not yet been documented. Symptomatic of this condition, which can be caused by the action of an additional ingredient in the solution in the form of lidocaine hydrochloride, can be the presence of noise in the ears, tremors, dizziness, drowsiness, anxiety, depression, nervousness, blurred vision, numbness of the lips and tongue.

In case of suspected overdose, the respiratory function and the proper functioning of the cardiovascular system should be monitored. If the changes corresponding to the above parameters are detected, then this will indicate the use of the drug in doses significantly exceeding the permissible standards. As a result, the patient will need immediate access to oxygen. Therefore, if any complications occur, symptomatic treatment should be started.

Specific instructions for the use of ampoules "Sustagard Arthro"

Instruction for use indicates that the injection solution should be used with caution in the presence of bronchial asthma, or impaired susceptibility of the body to glucose. Patients who observe a strict salt-free diet should take into account that one dose of the drug contains forty milligrams of sodium. Before intramuscular injection, a skin test is required to determine whether there is individual sensitivity to lidocaine. In carrying out this experiment, it is important to know that this sensitivity is expressed by the appearance of edema and reddening of the site of administration of the substance.

During the treatment with this drug, it is important to be careful while driving the car, or when using machinery, which requires increased concentration. This is due to the fact that after the injection of the medicine is likely the occurrence of sudden dizziness, drowsiness and double vision in the eyes. This is confirmed to the ampoules "Sustagard Artro" instruction and feedback. Analogs are discussed below.

Drug interaction of a medical device

Glucosamine sulfate is allowed to be used in combination with non-steroidal anti-inflammatory drugs, as well as glucocorticosteroids and paracetamol including. When using this drug with penicillins, the absorption of substances from the digestive tract decreases, and in the case of admission with tetracyclines, on the contrary, it increases. The reactions observed when combining lidocaine, which is contained in the solution of "Sustagard Arthro" with other medicines, are usually as follows:

• With "Phenytoin", the cardiodespressant effect of lidocaine is enhanced.
• As part of a combination with antiarrhythmic drugs, such as "Dizopiramid" and "Quinidine," atrioventricular blockade develops, or ventricular fibrillation may occur.
• Against the backdrop of Peptidine, Propranolol, Cimetidine and Chlorpromazine, the concentration of lidocaine in the blood plasma increases, and the hepatic metabolism of this substance is significantly reduced.
• Under the influence of ethanol there is an intensification of the inhibitory effect of lidocaine on breathing. And in conjunction with "Prokainamidom" probably the appearance of hallucinations and delirium.
• Drugs that have a sedative effect, when combined with "Sustagard Arthro" are enhanced their soothing effect.
• Medical drugs that predetermine the blocking of neuromuscular transmission increase the effect due to a decrease in the conduction of impulses of the nervous system according to the instructions for ampoules "Sustagard Arthro".According to reviews, the price is quite high.

Analogues of the drug

Analogues of this drug are solutions intended for intramuscular injection, which are medical products of the "Don" and "Elbon".Before replacing the prescribed drug with one of these analogs, the patient should always consult a doctor in charge.

Storage and dispensing conditions of

According to the instructions and reviews, the ampoules "Sustagard Artro" are dispensed in pharmacies strictly according to the doctor's prescription. Keep this drug in a dry and dark, as well as a cool place that is not available for children. Shelf life of the funds is two years from the date of issue. In Russian pharmacies the average price of the drug is seven hundred and fifty rubles.

Reviews about the drug "Sustagard Arthro"

A few reviews on the Internet about the drug "Sustagard Arthro" are mostly positive. People who used this drug, mark its effectiveness against the background of treatment of osteoarthritis, arthrosis, as well as osteochondrosis.

People write that this medication significantly relieves the symptoms of the diseases, giving an analgesic effect. In some situations, patients experience a slight feeling of pain when performing injections, which persists for some time.

There are no complaints about any side effects in the comments. But the main drawback of the drug is an extensive list of contraindications, as "Sustagard Artro" can not be accepted by all patients. For this reason, before you start treatment with this medicine, you need to undergo a medical examination and get advice from your doctor.

We have reviewed the "Sustagard Artro" instructions for the use of the solution, as well as reviews and analogues.