"Butadion"( tablets): instructions for use, analogues, price and reviews

What is the purpose of and how to use the drug "Butadion"( tablets)?Instructions for use, indications, properties and features of this drug will be presented in this article.

Also in it you will find information about how much it costs, what ingredients are included in its composition( active and inactive) and whether it has side effects. butadione tablets

Composition and packaging of medicament

What components are contained in the preparation of Butadion? Tablets include an active substance such as phenylbutazone. Also in the composition of the drug include: potato starch, impellose, magnesium stearate, sodium bicarbonate, talc and silicon dioxide.

The drug Butadion( tablets) goes on sale in blisters, which are enclosed in cardboard packages.

Pharmacodynamic characteristics of the drug

Do you know what a drug like Butadion is? Experts say that this is a non-steroidal anti-inflammatory drug that has antipyretic and analgesic effect.

The efficacy of this agent is related to its ability to inhibit cyclooxygenase activity. As a result of this effect, the synthesis of prostaglandins is slowed down.

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This medication enhances the re-absorption of salts and water in the renal tubules. It also eliminates pain syndromes and reduces swelling, which often accompanies inflammatory processes.

How does the therapeutic effect of Butadion appear? Tablets reduce pain in the joints( during motion and at rest), and restore their mobility or increase the volume of movements.

The anti-inflammatory effect of this remedy is largely superior to the effect of a similar drug, "Amidopyrin."

With gout, this medication doubles urate output along with urine, and also reduces their amount in the blood. butadione tablets

It should also be noted that the drug "Butadion"( tablets), the instruction for which is enclosed in the package together with blisters, reduces pain and signs of inflammation with thrombophlebitis( postoperative and hemorrhoidal veins).

Kinetic features of the preparation

Where is the drug Butadion( tablets) absorbed? The instruction informs, that high absorption of this medicine occurs from GASTROINTESTINAL TRACT.Its bioavailability is about 87-90%, and the maximum plasma concentration is observed 60-150 minutes after administration.

From the blood, the drug gradually passes into tissues and organs, and also penetrates into the joint cavity and through the blood-brain barrier.

Metabolism of this agent is carried out in the liver. Its half-life is 19-25 hours. Drug is withdrawn through the kidneys and through the digestive tract.

Indications for taking

tablets. In what cases is Butadion administered? Tablets are effective in treating:

  • Bechterew's disease;
  • of osteoarthritis;
  • psoriatic arthritis;
  • rheumatoid and lupus arthritis;
  • bursitis and tendovaginitis;
  • gouty arthritis;
  • algodismenorei;
  • postoperative pain syndrome;
  • dental and headache.

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This medication is also used to relieve unpleasant sensations in neuralgia, burns and radiculitis.

Contraindications to taking medication

How much does the drug we are considering? What is its price?"Butadion" can be purchased at any pharmacy at a very reasonable cost. We will present it at the very end of the article.

Are there any contraindications to this medication? According to the instructions, this medication is prohibited to be used with:

  • bleeding from the digestive tract in history;
  • acid intolerant acetylsalicylic;
  • heart rhythm disturbances;
  • hypersensitivity to phenylbutazone;
  • bone marrow suppression;
  • exacerbation of ulcerative colitis and peptic ulcer of the gastrointestinal tract;
  • decompensated CHF;
  • hepatic and renal insufficiency;
  • hyperkalemia;
  • under the age of 12;
  • pregnancy, especially in the first and third trimesters;
  • concurrent administration of other medicines that contain phenylbutazone.

butadione tablets instruction

Instruction for the use of the drug "Butadion"

According to the instructions, the drug "Butadion" is taken orally after meals, 150 mg four times a day. The largest single dose of this medication is 200 mg and the daily dose is 600.

The duration of therapy with this drug depends on the severity of the disease and the condition of the patient. The dose of the drug, equal to 400-600 mg per day, can reduce the amount of urine in diabetes insipidus.

Adolescents with 12-year-old tablets "Butadion" appoint 75 mg three times a day. In order to prevent the irritant effect of this drug on the gastric mucosa, it is recommended to wash it with warm milk.

In the presence of joint diseases, the effect of the medication is enhanced by the simultaneous administration of "Prednisolone"( drip, intravenously).

It should also be noted that, to increase the therapeutic outcome, Butadion tablets are combined with Butadion ointment.

Side effects after taking

tablets Taking Butadion tablets can cause the following systemic reactions:

  • nausea, abdominal pain, dyspepsia;
  • vomiting, aphthous stomatitis, heartburn;
  • ulceration of the mucosa of the digestive tract, diarrhea, tinnitus;

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  • gastrointestinal bleeding;
  • bleeding gingival and hemorrhoidal;
  • increase in blood pressure;
  • hepatic dysfunction;
  • headaches, anemia, depression, leukopenia, dizziness;
  • drowsiness, agranulocytosis, agitation, thrombocytopenia.

Side effects from the blood require withdrawal of the drug and contact a specialist.

Delayed water and sodium in the body, associated with the reception of "Butadione", significantly worsens the condition of patients with hypertension and CHF.This point also requires an adjustment in treatment.

Similar drugs and the price of

"Butadion" in tablets( 20 pieces) can be purchased for 40-70 rubles.

As for the analogues, the following means are used as such: "Butadion-OBL", "Artrisin", "Phenylbutazone", "Butalidone".

Reviews of patients about the drug

Now you know what the price of the drug "Butadion" is. Tablets are inexpensive, but as for the reviews, they will be presented below. butadion reviews

Analyzing the responses of patients about this drug, we can safely conclude that it effectively manifests itself in any joint and muscle pain. But, in addition to positive feedback, patients often make negative reports about him. According to them, tablets "Butadion" quite often cause complications from the organs of the gastrointestinal tract and blood. In this regard, most doctors recommend that you stop taking this medication and replace it with a safer means.