"Augmentin EU": instructions for use and feedback

No one is immune from infectious diseases. Especially vulnerable is a weak child's body. To treat babies at the age of 3 months, doctors often appoint "Augmentin EU".It is a powerful antibiotic, which has the form of a suspension. In order for children to accept the drug willingly, the manufacturer gave it a pleasant berry taste.

Basic information about

"Augmentin EC" is a powder from which a suspension for oral administration is prepared. The drug is packaged in vials, the contents of which are sufficient for the preparation of 100 ml of the drug. The dosage of the active substance( amoxicillin) is 600 mg. As an auxiliary, clavulanic acid in the amount of 42.9 mg, silicon dioxide, sodium carboxylate, aspartame, xanthan gum, and strawberry flavor, which will facilitate the use of the drug for young children, acts.

Basic properties of

"Augmentin EC" is an antibiotic of a wide range of effects, which is semi-synthetic. Amoxicillin shows increased activity against a large number of pathogens. Nevertheless, it is sensitive to beta-lactamase and is destroyed under its influence. Thus, amoxicillin is ineffective in controlling microorganisms that produce this enzyme.

Clavulanic acid is characterized by a structure that in many ways resembles penicillin. This causes a pronounced activity against beta-lactamases, which often cause the development of resistance to antibiotics. Thus, the presence of this acid in the drug "Augmentin EC" protects the main component from destruction under the influence of various kinds of enzymes and expands the spectrum of its antibacterial action. Thus, even those bacteria that are usually resistant to amoxicillin are killed by this drug.

It can be said that "Augmentin EC"( suspension) shows the properties not only of an antibiotic, but also of a beta-lactamase inhibitor. The bactericidal properties of a relatively wide range of microorganisms make this drug particularly effective. It should be noted that both amoxicillin and clavulanic acid are characterized by a low degree of binding by blood proteins. Thus, more than 70% of the active substance remains in the plasma in an unchanged state.

Main indications of

Physicians have already managed to evaluate the effectiveness of such a medicinal product as "Augmentin EC"( suspension).It is prescribed to patients who have been diagnosed with the following problems:

• bacterial infections of the upper respiratory tract, as well as of the ears, nose and throat( microorganisms should not have resistance to the active components of the antibiotic in question);
• resistant or recurrent otitis media( as a rule, this drug is administered to children if other antibacterial agents are ineffective);
• sinusitis and tonsillopharyngitis;
• lobar, bronchopneumonic and other infections of the lower respiratory tract;
• skin infections, as well as inflammation in the soft tissues.

Contraindications

Unfortunately, not everyone can take such a drug as "Augmentin EC"( suspension for children).The instruction contains information on such basic contraindications:

• hypersensitivity to the active components of the drug, which can be detected in the laboratory;
• presence of jaundice;
• hepatic dysfunction, which was caused by the reception of "Augmentin" in the past.

"Augmentin EC" preparation: instruction for use on children

In order for the medicine to have the right effect on the body, it is important to take it correctly, observing the schedule and the recommended quantities."Augmentin EC"( suspension for children) is usually taken within 10 days. In this case, the drug should enter the body twice a day, with an interval of 12 hours.

It should be noted that this medicine is allowed to give to children over 3 months of age. At the same time, clinical studies have confirmed the effectiveness of the drug in the treatment of patients whose body weight did not exceed 36 kg. For children heavier than 40 kg, as well as adult experiments were not conducted, and therefore it is impossible to talk about its effectiveness.

Depending on the body weight of the child, the amount of the drug "Augmentin EC-600"( suspension for children) is determined. The dosage is as follows:

Body weight of the child( kg)	8	12	16	20	24	28	32	36
Single dose suspension( ml)	3	4,5	6	7,5	9	10,5	12	13,5

It should be noted that this dosage is valid only for the preparation in question."Augmentin EC"( suspension for children) is characterized by a unique ratio of active and auxiliary components that are not characteristic of any other form of "Augmentin".

How to minimize the negative effect on the stomach?

The antibiotic "Augmentin EC-600", like any other similar agent, has a negative effect on the stomach and on the digestive system in general. To minimize this harmful effect, it is recommended to take the suspension during meals( ideally - at the very beginning of the meal).This way of consumption not only provides protection of the walls of the stomach, but also promotes optimal absorption of active components.

How is the suspension prepared?

In the form of a powder, which is contained in a small vial, enters the pharmacy chains "Augmentin EU-600".Turning the powder into a medicinal potion is not at all difficult. Suspension for children is prepared as follows:

1. In a bottle with a powder of 100 ml, add 90 ml of water( do this in two sets).
2. First you need to enter about 2/3 of the total volume of liquid, so that the powder is completely covered with water.
3. The vial should be closed with a lid and thoroughly shaken to bring the contents of the container to a uniform liquid state.
4. Add the rest of the set volume of water( note the mark on the bottle) and shake well again.
5. Leave the vial filled with the suspension in rest for 5 minutes, so that all the components of the preparation are connected together( the process of dispersion).
6. If you did everything correctly, you should get a white liquid that has a grayish or yellowish hue.

Possible side effects of

Like any other antibiotic, it leads to some side effects of "Augmentin EC-600"( suspension for children).The instruction contains information about the following possible problems:

Scope	Negative manifestations
Infections	Lesion of the skin and mucous membranes with candidiasis.
Circulatory system	Revolving leukopenia or neutropenia;hemolytic anemia, agranulocytosis, thrombocytopenia, an increase in the duration of bleeding.
Immunity	Angioedema;a syndrome of serum sickness( or conditions similar to it);vasculitis;anaphylaxis.
Nervous system	Dizziness;headache;convulsions( may be caused by excess of the recommended dose or problems with the kidneys);hyperactivity.
Digestive system	Stool disorders;nausea and vomiting( can be caused by taking too large doses or not eating at the beginning of the meal, indigestion, colitis( antibiotic-associated, pseudomembranous, hemorrhagic), changing the color of tooth enamel( this side effect can be eliminated by enhanced oral hygiene)
Liver and urinary system	Moderate increase in the level of AST and ALT, cholestatic jaundice or hepatitis( general adverse reaction for all antibiotics of the penicillin group), liver problems( in childrenmales and elderly patients are at risk)
Skin covers	Allergic rashes, urticaria, pruritus, erythema, Stevens-Johnson syndrome, epidermal necrolysis of toxic nature, bullous dermatitis, acute generalized pustulosis. In any adverse reactions withside skin integument treatment with this drug should be stopped
Kidneys and urinary tract	Nephritis interstitial, crystalluria.

It is worth noting that many side effects occur after the end of the medication "Augmentin EC-600".Instructions for use contain information that the first manifestations may occur even a few weeks after cancellation.

Overdose

It is necessary to strictly follow the instructions during the administration of the drug "Augmentin EC"( suspension).Dosage for children should be strictly observed, in order to avoid unpleasant consequences. If the child has taken more medicine than prescribed by the instructions, there may be a breakdown in the work of the gastrointestinal tract, as well as dehydration of the body. In this case, it is necessary to stop taking the drug and go to symptomatic treatment, paying special attention to restoring the water balance. In some cases, an overdose is accompanied by crystalluria. Then the doctor can decide on the use of hemodialysis to remove the drug from the blood.

Features of the use of the drug

The medical staff in the treatment of children with the antibiotic "Augmentin EU" has a fairly large experience. The instruction contains a lot of useful information regarding the correct administration of the drug. Nevertheless, given a fairly aggressive formula, we can talk about some of the features that accompany the process of treatment. So, we are talking about the following:

• Before starting to take the drug, you need to undergo a full medical examination for the detection of allergic reactions or individual intolerance to any components of the medication.
• If the patient has had a negative reaction to penicillin in the past, do not use Augmentin. This can lead to hypersensitivity, which often leads to death.
• If an allergic reaction occurs, take "Augmentin" immediately. Next, you should go to a doctor who will prescribe symptomatic treatment and alternative therapy.
• Anaphylactic reactions often require emergency treatment with adrenaline. In addition, oxygen therapy, as well as intravenous administration of steroids and intubation for the purpose of maintaining respiratory function, may be prescribed.
• When suspected of infectious mononucleosis treatment "Augmentinom" categorically contraindicated. Otherwise, there is a high likelihood of a rash, which is similar to measles.
• Prolonged use of the drug may trigger the activation of microorganisms that are insensitive to "Augmentin EU".
• In general, the drug is tolerated by patients well, because it has low toxicity. However, with prolonged use, regular monitoring of liver and kidney function is necessary.
• Occasionally, there may be problems with blood circulation and blood clots. Particular attention is required by the patient's condition with parallel administration of anticoagulants.
• Patients who are diagnosed with liver dysfunction, "Augmentin EU" should be taken with extreme caution and under continuous medical supervision.
• In patients with impaired renal function, the dosage should be adjusted, in accordance with the state of health and diagnostic parameters.
• When using the drug in patients with decreased urinary secretion, crystalluria can be observed. To minimize the likelihood of such manifestations, it is necessary to regularly monitor the balance between the consumed liquid and the urine withdrawn from the body.
• Given that the composition of the drug in question includes asparks, it should be used with caution in patients diagnosed with phenylketonuria.
• In the course of laboratory studies and experiments, there was no adverse effect on the ability of patients to drive vehicles and other mechanisms. In principle, this indicator can not be considered significant, given that the suspension is prescribed, mainly to children.

Drug Interaction

For patients taking "Augmentin EC", the instructions for use set some restrictions on the simultaneous use of certain drugs. Thus, concurrent use of Probenecid is not recommended, which reduces the renal secretion of amoxicillin. Prolonged simultaneous application may lead to an increase in the level of amoxicillin in the blood, but does not affect the concentration of clavulanic acid.

Simultaneous application of "Allopurinol" leads to an increase in the likelihood of allergic reactions( especially skin reactions).There were no deeper studies on this issue. Also, attending physicians should warn their patients that "Augmentin", like any other antibiotics, reduces the effectiveness of oral contraceptives. But for the means described in the article, this information does not matter much.

Admission during pregnancy and lactation

Studies that have been conducted on animals have not revealed any teratogenic effect. Thus, the risk of congenital anomalies of the fetus when taking "Augmentin" does not increase( in comparison with other antibiotics).With regard to the practical use of this drug by pregnant women, there is an increased risk of necrotizing enterocolitis in newborns. Thus, during the period of gestation, it is better to refrain from using this drug, unless the expected benefit does not exceed the possible risk.

Speaking about the period of lactation, it is worth noting that the active components of the drug are excreted into breast milk. There is no data on the negative impact of these substances on the development of an infant who is breastfeeding. Nevertheless, he may have stool and fungal infections of the mucous membrane. Thus, if the doctor found it necessary to appoint a woman "Augmentin", breastfeeding for this period should be discontinued.

Analogues

If for some reason you can not accept the "Augmentin EU", you can choose one of the many analogues that are on the market. So, according to the action, the following drugs are most similar:

• "Abiklav" is a semisynthetic antibiotic based on the action of amoxicillin and potassium clavulanate. Many grampositive and gram-negative anaerobes and others are sensitive to it. The drug is prescribed for bacterial sinusitis, otitis media, chronic bronchitis in the acute phase, cystitis, pneumonia, infections of the skin and soft tissues, as well as bones and joints.
• "A-Clave-Farmex" is a powder for the preparation of a solution for intravenous injections. The drug belongs to the group of antibacterial agents for systemic use. The basis of the antibiotic is a mixture of amoxicillin and potassium clavulanate. The drug shows good results in the treatment of mixed infections, diseases of the ENT organs, as well as other bacterial infections.
• "Beta" is an antibiotic for systemic use, which includes amoxicillin trihydrate and potassium clavulanate. These are small oval tablets covered with a white film shell. This is a semi-synthetic agent with pronounced antibacterial activity. It also has the properties of a beta-lactamase inhibitor, which determines the activity of a relatively wide range of pathogens. The drug is prescribed for bacterial sinusitis, otitis media, chronic bronchitis, pneumonia, cystitis, as well as infections of tissues and bones.
• "Coact" is a white granular powder for the preparation of an oral suspension. The chemical composition is based on amoxicillin and potassium clavulanate. As with previous drugs, this drug is indicated for bacterial diseases of the ENT organs, exacerbation of chronic bronchitis, cystitis, pyelonephritis, as well as skin, bone and tissue infections. Auxiliary substances of the drug expand the spectrum of its activity, activating the fight against microorganisms resistant to penicillin.

Positive feedback from

If your attending physician has appointed "Augmentin EC", the feedback will help you to orient yourself and make a final decision about taking this medication. So, from positive comments it is worth noting the following:

• preparation combines two active substances, which differ in pronounced antibacterial activity;
• suspension is prepared quickly and easily( enough to add cool boiled water);
• quickly copes with complex diseases;
• in the package there is a detailed detailed instruction from which it is possible to obtain exhaustive information about the preparation;
• in the kit is a spoon, which is easy to measure the required amount of suspension;
• the medicine smells good with fruits and berries;
• , the improvement of the condition is often observed after the first day of taking the drug( provided that it was selected correctly).

Negative feedback from

Many controversial opinions can be heard about a drug such as "Augmentin EC"( suspension for children).Reviews contain such negative comments:

• the shelf life of the drug is 10 days, so if you do not have time to use the entire amount of suspension, the residue will have to be discarded;
• the drug is stored in the refrigerator, and therefore every time before taking it, it must be heated to room temperature;
• despite the fact that there is a berry flavor, the suspension has a rather specific taste, which is not very popular with children;
• at the time of taking the drug, many children lose appetite, which makes it difficult to use the suspension during meals;
• if you do not take funds to normalize the microflora, there may be indigestion and stool disorders;
• it is difficult to calculate the dosage, depending on the age and body weight of the baby( preferably if the doctor does);
• high price, compared with other similar drugs( about 400 rubles per bottle).

Conclusion

Many people consider the use of antibiotics undesirable, because they destroy not only the pathogenic, but also useful microflora of the body. Nevertheless, in order to prevent serious complications, specialists appoint their patients "Augmentin EU".Suspension for children, the instruction for use of which contains comprehensive information, has a pronounced effect. Despite the many side effects of antibiotics, the drug quickly copes with the problem, easing the condition from the first day of admission. But it should be borne in mind that self-medication is unacceptable. A doctor should appoint a medication!