"Pangrol 10000": instruction for children, reviews, analogues
Form, description, composition of medicament
In what form is Pangrol 10000 manufactured? The instruction, the reviews say that this preparation is made in the form of opaque gelatinous capsules. Their body is orange and the lid is green.
The contents of capsules are small cylindrical tablets. They have an enteric coating, a smooth surface and a beige color.
What substances are a part of the medicine "Pangrol 10000"?The instruction says that the active ingredient of this medicine is pancreatin. Also, the medicament includes additional components in the form of magnesium stearate, croscarmellose sodium, hydrogenated castor oil, colloidal anhydrous silica dioxide and microcellulose.
Features of
What is a medicine like Pangrol 10000?The instruction says that this medication is a digestive-enzyme agent. It replenishes the deficiency of enzymes, which are necessary for the normal functioning of the pancreas. Also, this drug produces proteolytic, amylolytic and lipolytic effects.
Principle of operation of
What is the mechanism of action of the drug "Pangrol 10000"?The instruction indicates that the pancreatin contained in this medicine is a powder. It is obtained through the processing of animals of the pancreas( in particular, pigs).
Enzymes contained in it, have a beneficial effect on the digestive process. In addition, they accelerate the breakdown of proteins, carbohydrates and fats, help the normal functioning of the pancreas.
In view of the fact that the "Pangrol 10000"( instructions for use for children will be discussed later) promotes digestion of food, it quickly removes all signs of digestive disorders( for example, if there are shortness of breath, a feeling of heaviness in the abdomen, pain, stomach fullness, flatulence, etc.).
Taking capsules stimulates the small intestine, pancreas and stomach to produce enzymes that are directly involved in digestion.
The bile extract, which is part of the drug, promotes the emulsification of fats, acting on the human body in a choleric manner. This substance increases the activity of lipase, which improves the absorption and digestion of fat-soluble vitamins K, A and E, as well as fats that enter the stomach with food.
Pharmacokinetics
Is the drug "Pangrol 10000" absorbed? The instruction says that the capsules are coated with an acid resistant coating. It helps to protect the medicine from gastric juice. As a result, the drug unhindered enters the small intestine. In it, the capsule shell dissolves rather quickly and releases its contents, that is, mini-tablets. 
For the effective treatment of the drug in the small intestine it is necessary to maintain a slightly alkaline pH( or neutral).
This medication is not absorbed into the digestive tract. It is excreted through the intestine.
Indications for use
What can be used for "Pangrol 10000"?Instructions for use for children and adults indicate that this medication is prescribed, if necessary, for the replacement of exocrine pancreas. In addition, the agent in question is used for an enzymatic deficiency caused by one of the following diseases:
- Schwamman-Diamond Syndrome;
- cystic fibrosis;
- irritable bowel syndrome;
- narrowing of the pancreatic ducts;
- presence of gallstones;
- malignant tumor;
- intestinal infections;
- pancreatitis( chronic or preponderant stages);
- disorders of the gastrointestinal tract.
What other purposes can Pangrol 10000 be appointed for? Instruction for children and adults says that this medication is used as a preparation for x-ray or ultrasound examination of the abdominal cavity. In addition, the capsules are taken to restore the normal functioning of the stomach and pancreas after surgery, as well as in the complex treatment after radiation therapy with symptoms such as indigestion, gas and diarrhea. 
Contraindications
Under what conditions can not take the capsule "Pangrol 10000"?Instruction for children, expert reviews report the following prohibitions:
- acute pancreatitis;
- hypersensitivity;
- exacerbation of pancreatitis.
How to use for young children
In what dose is Pangrol 10000 prescribed? Instruction for children says that the amount of this drug should be determined only by an experienced pediatrician. As a rule, the dosage of the medicine is calculated according to the following scheme: 500-1000 units of lipase for each kilogram of the weight of the baby.
The duration of therapy depends on the patient's health, the type and severity of the illness. If the child can not take the whole capsule, then its contents are mixed with water or food that you do not need to chew( for example, porridge or fruit puree).The resulting mixture should be consumed immediately. It is forbidden to keep it.
In the treatment of cystic fibrosis, the volume of the drug also depends on the weight of the child. The initial dosage for babies up to four years is 1000 units of lipase per kg of weight, and for children older than this age, 500 units.
When using the drug in pediatric practice, it is necessary to follow a strict diet in order to exclude the development of steatorrhea. 
Dosage for adults
Capsules "Pangrol 10000" must be taken with food. They are not chewed, but swallowed whole, washed down with water.
The dose of the medicine is determined by the therapist or gastroenterologist( depending on the patient's condition, shape and severity of the disease).As a rule, adults are prescribed two to four capsules a day. If necessary, the doctor can increase the daily dose of the medicine.
Side effects of
Adults and children may experience adverse reactions such as diarrhea, nausea, abdominal pain, vomiting, bloating, and other digestive disorders when taking this medication in children and adults.
Very rarely, patients are allergic to the drug "Pangrol".Usually it is expressed in the appearance of hives, itching or rash on the skin.
If these effects are found, stop taking the medication and consult a doctor.
Cases of overdose
There are few reviews of an overdose of Pangrol. As a rule, with an increase in the number of enzymes during the treatment of cystic fibrosis, diseases such as hyperuricosuria and hyperuricemia occur. 
Special recommendations for taking
Before taking Pangrol capsules, always read the attached instructions. It says that during the treatment of cystic fibrosis in people who received large doses of the drug, fibrosing colonopathy( that is, strictures of the blind, ileum or colon) may develop.
To avoid changes in the symptoms of the underlying disease, it is necessary to undergo a medical examination before taking this medication, which will exclude the presence of intestinal lesions.
The medicine in question does not affect the ability of the patient to drive vehicles, nor does it reduce the speed of his reaction while working with dangerous mechanisms.
Analogues and cost of the drug
Today, there are a large number of drugs to improve the performance of the pancreas and stomach. Structural analogues of the medicine "Pangrol" are the following: Hermitage, Gastenorm Forte, Pancrelipase, Creon, Enzistal-P, Mezim, Penzital, Mikrazim, Pancreatin Forte, Mezim Forte, Festal, PanziKam, Pancitrat, Panzinorm, Pancreatin-LekT, Pancreatin, PanzimForte, Panzinorm Forte.
As for the price, you can buy 20 capsules of this drug for 250-300 rubles.
Comments of consumers about the drug
Capsules "Pangrol 10000" are very popular among patients. Reviews about this drug are mostly positive. People who regularly take this medicine talk about its quick action and high efficiency. 
"Pangrol" significantly improves the digestion process, thereby eliminating the severity, pain and feeling of fullness of the stomach. Also, thanks to this medicine, you can get rid of excessive gas formation, nausea, heartburn and other unpleasant conditions that occur when taking fat and high-calorie food.
The only drawback of this drug is the complexity of calculating the dosage, especially for young children. In view of the fact that digestive problems are purely individual, only an experienced doctor can choose the right dosage. This fact significantly complicates the independent use of the drug.