"Nexium": cheap analog, instructions, reviews. How to take "Nexium"?
In our time, the pathologies of the gastrointestinal tract are encountered more often. Symptoms of ailment not only cause discomfort and pain, but can lead to serious complications. The patient has pain in the epigastric region, heartburn, belching, digestive disorders. To get rid of the disease, you need to undergo a checkup and begin treatment at the time. A fairly widespread and popular drug for eliminating stomach problems is Nexium. Instructions for use, feedback - all information can be found from the article.
The drug belongs to the group of ATPase inhibitors. Produced in the form of pills in pink. The main substance in the drug is esomeprazole at a dosage of 20 and 40 mg. Auxiliary components are:
- glyceryl monostearate;
- dye iron oxide is orange and red;
- magnesium stearate;
- microcrystalline cellulose;
- talcum powder.
Tablets are in blisters of aluminum, 7 pieces each. The product is packaged in packs with the first opening control for 1, 2, 4 blisters in each. How to take "Nexium", the doctor will tell before the beginning of the medical process. Basic information will also be provided below.
The main drug substance is considered an isomer of omeprozole, it reduces the effect of hydrochloric acid in the stomach by specifically inhibiting the proton pump in parietal cells. The maximum activity of the drug is observed in sixty minutes after administration. Taking tablets for a week at a dose of 20 mg, you can see that the average value of hydrochloric acid in the gastric secret decreases - in the mouth, the taste is less often felt.
The therapeutic effect is achieved by inhibiting hydrochloric acid in almost 100% of patients after a two-month course. Also during the treatment with a joint admission with antibiotics, the patient has a successful eradication of the Helicobacter pylori wand, which provokes ulceration. Before the beginning of treatment, the instruction for use should be studied for the Nexium preparation. Analogs will have a similar effect on the body.
Esomeprazole is resistant to acidic conditions. Therefore, the tablets are covered with a special film that is immune to gastric juice. After use, the medicine is quickly absorbed from the stomach. Its maximum activity is achieved within two hours. Almost 100% associated with plasma proteins. If you take food together with the medicine, the process of its absorption decreases and slows down in the stomach. The main metabolites of the drug have no effect on the secretion of the pancreas.
In the form of metabolites, the drug is excreted in the urine, and only a small part of it - with feces. In elderly patients, metabolism does not change when taking Nexium. The cheap analogue - "Esomeprazole" - has a similar pharmacokinetics.
Indications and contraindications
Medication can be prescribed for the following reasons:
- gastroesophageal reflux disease;
- elimination of the causes of erosive reflux esophagitis;
- maintenance therapy in patients after healing of ulcers in order to prevent exacerbation;
- treatment of peptic ulcers of the stomach and duodenum in combination with other drugs;
- preventive measures of relapse of peptic ulcer associated with the bacterium Helikobakter Pilori;
- long-term treatment after gastric bleeding;
- ulcer healing associated with NSAID administration;
- pathological hypersecretion.
- fructose intolerance, which is hereditary;
- insufficiency of sucrose and glucose;
- age is up to 12 years;
- children's age after 12 years, except for patients with gastro esophageal reflux disease;
- complex reception together with "Atazanavir" and "Nelfinavir";
- kidney failure;
- hypersensitivity to the main substance - esomeprazole.
Before starting therapy, it is advisable to thoroughly study all the indications and contraindications that the medical tool "Nexium" has. Analogues Russian also should be used after consultation with a doctor.
Tablets are taken orally, without chewing and squeezed with a small amount of liquid. The medicine is covered with a special film that is resistant to gastric juice. The tablet can not be broken. Those patients who can not swallow the whole drug, it is necessary to dissolve it in half a glass of water without gas and after a while to drink. For long-term use, after the erosive esophagitis transferred, 20 mg of the remedy are prescribed to avoid relapse. The medicine should be taken once a day.
In the treatment of gastroesophageal reflux disease, adults and children weighing more than 30 kg are prescribed a drug at a dose of 20 mg per day. If the symptoms do not disappear for a month, then an additional examination is necessary. After recovery, you can take pills as needed when symptoms occur. The dose in this case is 20 mg once a day. Those patients who take NSAIDs and are at risk associated with a stomach ulcer, only after consulting a doctor should use the medicine "Nexium".Analogues, reviews - all this information should be clarified before the start of therapy.
In ulcerative pathologies associated with the bacterium Helicobacter pylori, the drug is used as part of a complex therapy of 20 mg per day. In addition, amoxicillin( 1 g) and clarithromycin( 500 mg) are prescribed. Complex therapy is carried out for ten days.
For the purpose of acid-suppressing therapy for patients who underwent gastric bleeding, the drug is administered at a dose of 40 mg per day for one month.
Interaction with other drugs
The drug is not recommended at the same time with the following medicines:
If the patient is taking one of these remedies, the physician should be informed about this before starting the use of Nexium. A cheap analog will have the same recommendations.
When using medicament in elevated doses, the patient may develop weakness, nausea and other symptoms of intoxication. There is no specific antidote to the drug. Therefore, in this case, symptomatic and supportive therapy is prescribed. Dialysis here is ineffective, since the main substance of the drug is almost 100% associated with blood proteins.
Pregnancy and lactation
The use of Nexium during the gestation of a child has been little studied. It can be prescribed only in exceptional cases, when the prospective benefit for the expectant mother is greater than the risk for the fetus. According to the results of animal studies, there was no adverse effect on the embryo, which could provoke ugliness or underdevelopment. During breastfeeding it is better to refrain from using the medication. The drug enters the milk. If there is a need for therapy, it is advisable to give up lactation.
If you take the medicine incorrectly, the following unpleasant symptoms may develop:
- the occurrence of allergic reactions, up to anaphylactic shock;
- pain in epigastrium;
- muscle weakness;
- sleep disturbance;
- impaired renal function.
If you have any side effects, tell your doctor. How to take "Nexium" to avoid an overdose, the doctor will be able to tell at the reception.
The drug should be stored away from children, at a temperature of not more than 30 degrees. In the pharmacy is released on prescription. It is not recommended to prescribe to children under 12 years, with the exception of the need for therapy of gastroesophageal reflux disease. For patients with severe renal failure, the dose of the drug should not exceed 20 mg per day.
In the process of treatment, it is better to abandon driving vehicles and work related to concentration. Often, dizziness occurs due to taking pills. A preliminary instruction must be studied to the "Nexium" tool. The reviews show that side effects often develop in patients who neglect the recommendations.
Cheap analogue - the drug "Esomeprazole"
The drug belongs to the group of antiulcer, is an inhibitor of the proton pump. Also, the active substance reduces the secretion of hydrochloric acid. A positive result is observed already an hour after taking 20 or 40 mg of the drug. If you take the medicine every day for five days, you can reduce the level of hydrochloric acid by almost 80%.
The drug is unstable to an acidic environment. Therefore, granules and tablets are coated with a special coating that can come into contact with gastric secretion.98% of the drug binds to blood proteins. The same action is provided by the medicine "Nexium".The cheap analogue of "Esomeprazole" practically does not differ in composition.
Indications and contraindications
"Esomeprazole" may be prescribed in the following cases:
- treatment of erosive esophagitis;
- preventive measures with already cured erosive reflux esophagitis;
- symptomatic treatment of GERD;
- in combination with antibiotics to kill the bacterium Helicobacter pylori, which causes a stomach ulcer and duodenal ulcer.
- Hypersensitivity to the drug;
- severe form of kidney failure;
- age to 16 years.
How to take medicine?
"Esomeprazole" is administered orally. Dosage is set individually, taking into account the severity of the disease. In general, it is 20 or 40 mg once a day. Tablets can not be chewed and crushed. It is covered with a special coating, which helps the drug to be absorbed into the stomach. If there is no possibility to swallow the whole medicine, then it can be dissolved in a glass of still or boiled water and after 30 minutes a drink.
In renal pathology, the drug is dosed at a rate of 20 mg per day. The algorithm of reception at means "Nexium" is identical. Analogues are cheaper often have similar recommendations.
Side effects of
The following unpleasant symptoms may develop if the drug is taken incorrectly:
- muscle weakness;
- sleep disturbance;
- allergic reactions;
- tremor, etc.
Reviews about Nexium and Esomeprazole
Most patients prefer to undergo treatment with these medications. The Russian analog has a more affordable price, which is about 30 rubles per package. But the imported original has a rather high cost( about 800 rubles).According to the patients, there is no significant difference in these medicines, so there is no need to overpay for "Nexium".Instruction, analogues, their cost - all this information is desirable to study, before proceeding to treatment.
The described medicines are transferred well, in a short time you can get rid of the pain, which is caused by a high content of hydrochloric acid in the gastric juice. They also help to heal the ulcer and not cause repeated relapses. In combination with antibiotics, the patient gets rid of the Helicobacter pylori bacterium, which often leads to gastric ulcer and duodenal ulcer.
Only by prescribing a doctor you need to start treatment with Nexium. A cheap analogue of "Esomeprazole" is also not worth using alone.
The active ingredient does not cause addiction and withdrawal symptoms. Tablets are convenient to take. They have a shell, which does not cause irritation of the mucosa in the stomach and helps the drug to be rapidly absorbed. On each tablet( their color is pink) there is a marking from the manufacturer, which protects the medicine from forgery. Many gastroenterologists in their practice use the "Nexium" and its cheap analogue - the drug "Ezekeprazol" - for the treatment of stomach diseases of different etiologies. Specialists note that the medicines described above do show a good result of therapy.