"Tsinarin": instructions for use, reviews, analogues

Calcium channel blockers are called a heterogeneous group of drugs that have the same principle of action, but differ in some properties, including kinetic parameters, tissue selectivity and the effect on heart rate.

The main principle of the action of such medicines is that they are able to inhibit the penetration of Ca ions from the intercellular space into blood vessels and heart muscle cells through calcium channels( slow ones).This leads to a pronounced vasodilating action. cinarine instructions for use

The most popular calcium antagonist is the drug "Tsinarin."Instructions for use, cost, reviews and composition of this tool will be described below.

Form release, packaging, description, composition

The drug "Tsinarin", whose reviews are positive, goes on sale in the form of biconcave, round and white tablets. Their main component is cinnarizine. In addition, the composition of the drug includes auxiliary substances in the form of povidone K25, lactose, wheat starch, silicon dioxide colloid and magnesium stearate.

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You can purchase this tool in contour cells.

Characteristics of the preparation

Instruction for the use of the drug "Tsinarin" reports that it is a selective antagonist of calcium channels( slow).It reduces the flow of Ca ions into the cells and reduces their number in the depot of the plasmolemma, and also enhances the vasodilating effect of carbon dioxide and reduces the tone of the musculature of the arterioles.

Acting directly on the vessels, this drug significantly reduces their response to nutrients( norepinephrine, adrenaline, angiotensin, dopamine and vasopressin).It should also be noted that the medication in question has vasodilating properties, including those related to cerebral vessels. In this case, it does not affect BP.

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The drug "Tsinarin", the price of which is indicated below, shows a moderate antihistamine activity, reduces the excitability of the vestibular apparatus and reduces the tone of the sympathetic NA.This drug effectively manifests itself in the initial failure of cerebral circulation, as well as in chronic. In people with impaired peripheral circulation, it improves the blood supply of all tissues and organs. It also reduces blood viscosity, increases the elasticity of erythrocyte membranes and muscle resistance to hypoxia.

Kinetics of the drug

What are the kinetic features of the drug "Cynarine"?Instructions for use say that this remedy resorbed in the intestines and stomach. The peak of its concentration in plasma is reached after three hours. The connection of cinnarizine with plasma proteins is 91%.The drug is completely metabolized in the liver. Its half-life is four hours. There is a drug with urine and calves.

dispensing of medicines


The drug "Tsinarin" is indicated for use with:

  • senile dementia;
  • ischemic stroke;
  • craniocerebral trauma;
  • post-stroke states( including hemorrhagic stroke);
  • of discirculatory encephalopathy;
  • for the prevention of kinetosis( sea or air sickness, as well as for motion sickness);
  • vestibular disorders( including Meniere's disease, tinnitus, dizziness, nystagmus, vomiting and nausea of ‚Äč‚Äčlabyrinthine origin);
  • migraines( for the prevention of seizures);
  • peripheral circulatory disorders.

Contraindications to the ingestion of tablets

Under what conditions can not prescribe the drug "Tsinarin"?Instruction for use informs that this remedy is contraindicated when:

  • hypersensitivity;
  • of fetal bearing;
  • Breastfeeding.

It should also be noted that this drug is administered with caution in Parkinson's disease.

Preparation "Tsinarin": instruction for use

Take the tablets to be taken inside, preferably after a meal.

In case of impaired blood circulation of the brain, the drug is prescribed in the amount of 25-50 mg three times a day, and in the case of impaired peripheral circulation - 50-75 mg with the same multiplicity.

For vestibular disorders, the drug is recommended to take 25 mg three times a day. With kinetosis or the so-called "road" disease, adult patients are prescribed 25 mg of the drug 30 minutes before the road. If required, the medicine is taken again after 6 hours( in the same amount).

instructions for use

For children, this drug is prescribed in an amount of 1/2 dose from an adult.

With high sensitivity to medicine, therapy is started with half the dosage, gradually increasing it. The course of treatment can last from 2-3 weeks to several months.

Side effects of

This drug can cause the following adverse reactions:

  • dry mouth, indigestion, epigastric pain, cholestatic jaundice;
  • drowsiness, headaches, fatigue and extrapyramidal disorders( eg, increased muscle tone, limb tremor, hypokinesia);
  • red flat lichen, sweating, lupus-like syndrome, skin rash;
  • allergic phenomena, weight gain, lowering blood pressure.

Price, product release, analogues and reviews about it

The release of drugs related to the calcium channel blockers group is carried out according to a doctor's prescription. The price of this medicine is about 20-50 rubles.

If necessary, this drug can be replaced with drugs: Vertizine, Diziron, Stugesin, Stugeron, Cinazine, Cynedil, Cinnarizine, etc.

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Most consumers who take this antagonist claim thatit is a very effective and effective drug. The reception of "Tsinarin" tablets helps to eliminate vestibular disorders and disorders in the process of circulation. In addition, this medicine positively affects the human body in case of migraines, senile dementia and post-stroke states.

It should also be noted that the agent in question often provokes adverse reactions. To avoid their development, all the doctor's recommendations should be strictly observed. Taking tablets "Tsinarin" in its personal discretion is prohibited. They should be prescribed only by the attending physician.