The drug "Ulkavis": reviews and analogues
The drug "Ulkavis"( reviews note that the drug works well for gastritis, improvements are noticeable on the 2-3 day of its use) is an antiulcer medication. Has bactericidal activity against Helicobacter pylori. Effective in many diseases of the gastrointestinal tract. It covers the mucous membrane of the stomach with a film, which facilitates its rapid recovery.
Composition and form of the preparation
The drug "Ulkavis" is produced in the form of tablets. The active substance is bismuth tricalium dicitrate in an amount of 303.03 mg, which corresponds to 120 mg of bismuth oxide. Additional components in the composition of the tablets are:
- corn starch;
- Povidone K30;
- potassium polycryline;
- macrogol 6000;
- magnesium stearate.
The shell of the pill consists of a transparent component of Opadry II, which includes elements such as polyvinyl alcohol and macrogol 4000. In addition to this substance, the composition of the shell includes talc and titanium dioxide.
Tablets "Ulkavis"( reviews note that the drug acts quickly and effectively) have a round shape and a white shell. They have a facet. Enclosed in an aluminum blister for fourteen pieces. The packaging box can contain two, four or eight blisters.
The preparation is produced in Slovenia by the company "KRKA".Must be stored in a dry, cool and protected from the sun place at a temperature mode of not more than + 25 ° C.Shelf life of pills is two years from the time of their manufacture.
The medicine is dispensed without a doctor's prescription. It costs about 300 rubles for 50 tablets. The price of 112 capsules is 500 rubles.
On the pharmacological effects of the drug
Antiulcer Ulkavis( reviews say that the tablets are cheaper than the popular analogue of "De-Nol") has a pronounced bactericidal activity with respect to Helicobacter pylori. It is endowed with astringent and anti-inflammatory properties.
Penetrating into the acidic environment of the stomach, insoluble citrate and bismuth oxychloride precipitate there, creating a special protein substrate. It is a protective film that forms on the surface of erosions and ulcers. The medication increases the synthesis of PGE, as well as the amount of mucus and the production of bicarbonate. Activates the activity of cytoprotective mechanisms. Increases the resistance of the gastrointestinal mucosa to the influence of hydrochloric acid, pepsin, various enzymes and salts. This action of the drug leads to the creation of a stock of epidermal growth factor in the area of the defect. Reduces the activity of pepsin.
The bismuth subcitrate is practically not absorbed from the gastrointestinal apparatus. It comes with feces. A small fraction of bismuth enters the bloodstream and is subsequently excreted by the kidneys.
Indications and contraindications
recommends the use of medication "Ulkavis"( tablets) as prescribed by the doctor. Indications for the administration of the drug is gastric and duodenal ulcer, which is in the acute stage, including that caused by Helicobacter pylori. Apply the drug for gastroduodenitis and chronic gastritis, when the development of the disease has reached a phase of exacerbation and there is a bacterium Helicobacter pylori. Prescribe pills for irritable bowel syndrome, accompanied by diarrhea. The purpose of using the drug is functional dyspepsia, which has nothing to do with organic pathologies of the gastrointestinal tract.
The drug "Ulkavis"( reviews note that with a stomach ulcer the drug helps in the first week of admission, pain passes, and the person begins to feel perfectly healthy) is not prescribed for individual intolerance of the components contained in the medication. It is forbidden to use the drug for renal failure, which is in a serious stage of development, when the level of Cl creatinine is less than 30 ml / min. The drug is contraindicated in pregnancy and lactation. Do not prescribe these pills to children who are under four years old.
During treatment, Ulcavis should consider the occurrence of side effects. Among them, a vomiting reflex, nausea, diarrhea, constipation. All these symptoms are temporary and after the drug is immediately withdrawn.
Taking tablets can cause rashes on the skin, itching. With prolonged use and high doses, there is a risk of encephalopathy, which is associated with a high content of bismuth in the central nervous system.
If you use the medication incorrectly, you may experience symptoms of an overdose, in which the kidney function is disturbed. All phenomena are completely reversible and after the discontinuation of the use of the drug pass.
Tablets "Ulkavis": instructions for use
Pills are taken orally for half an hour before meals, washed down with water and not chewing.
Adults and at the age of twelve years prescribed one tablet four times a day. You can take the medicine on two tablets twice a day.
Children of the age category from eight to twelve years of age medication are prescribed one pill twice a day. At the age of four to eight years, the daily dosage is taken at the rate of 8 mg of medicine per kilogram of the child's weight.
Therapeutic course lasts 1-2 months. In the next two months, it is forbidden to take medicines containing bismuth.
When Helicobacter pylori is eradicated, a combined treatment is performed. Here tablets "Ulkavis"( the instruction on application is applied to the preparation and must be carefully studied before its application) are prescribed together with antibacterial medicines characterized by anti-Helicobacter activity.
Thirty minutes before and after the use of Ulkavis, you can not take other medicines, food and any liquid, this will reduce the effectiveness of the medication.
If the tablets "Ulkavis" will be used together with tetracycline, then the absorption of the last drug will be reduced.
This medication is not recommended for more than two months. Do not exceed the dosage prescribed for children and adults. When treating Ulkavisom, it is prohibited to use medicines containing bismuth. After the treatment course, if the drug was taken in the recommended doses, the active substance content in the blood will not exceed 3-58 μg / l. Bismuth poisoning occurs at a plasma concentration of 100 μg / l.
May cause darkening of the feces preparation "Ulkavis"( tablets).The instruction notes that this is due to the formation of bismuth sulfite. In rare cases, for the same reason, there may be a darkening of the tongue.
Reviews of doctors
Strongly advises to adhere to the doses prescribed by the doctor, when using the drug "Ulkavis" instruction. The doctors' comments point out that the drug has an acceptable price and excellent therapeutic properties. Helicobacter pylori is effective. It has wound healing and antibacterial properties. Well proven in the treatment of gastritis and ulcers. The bismuth salts contained in the preparation envelop the sore spots and help them to heal. In combination with the diet gives excellent results. Has appeared rather recently, but has already time to prove from the best party. It is a complete analogue of the famous "De-Nol", but, unlike the latter, it is cheaper.
Doctors say that the drug rarely causes side effects and is well tolerated by patients. Despite the fact that the medicine gives a quick effect, doctors are advised to undergo a full therapeutic course and take the pill for at least a month.
Opinion of patients about the medicine
Warns that it is necessary to get acquainted with the contraindications before taking the drug "Ulkavis", instructions for use. People's reviews of this medication are in most cases positive.
Patients note that the drug acts quickly and effectively. Usually the relief of symptoms comes to the end of the first week of treatment of gastritis, ulcers and other pathologies of the gastrointestinal tract. Patients claim that the pills help to quickly remove pain, heartburn, nausea and bad breath. The medicine relieves exacerbation of gastritis and ulcers. It is often used in the complex treatment of Helicobacter pylori. The medicine covers the formed sores with a film and helps them to heal. Gently repairs the mucosa of the gastrointestinal tract.
The drug is convenient to take - two tablets twice a day, washed down with water. With diseases of the stomach and intestine, "Ulkavis" should be drunk for at least a month. Some doctors recommend to drink the remedy for two months continuously to fix the result. The appointment depends on the diagnosis and stage of the disease.
This medicine appeared on the market relatively recently, and therefore many patients treat it with distrust. First they buy a small package of medicine, and after a positive change they buy a big one.
Often "Ulkavis" is compared with the drug "De-Nol".The last resort has already proved itself. It has long been used effectively in the treatment of gastrointestinal diseases. Therefore, the replacement of "De-Nol" with "Ulkavis" often causes a lot of doubts in patients.
There are no negative reviews of this drug. In isolated cases, patients with nausea and diarrhea were treated with medication. The symptoms after the withdrawal of the drug quickly passed.
Recommends that the medicine "Ulkavis" be used only as prescribed by the doctor. Analogues to this drug are sold in each pharmacy and, if necessary, will help to replace it.
The most popular substitute for Ulkavis is De-Nol. Both preparations contain a bismuth salt. Analogues for this medication can be "Novobismol", "Escape", "Ventrisol", "Pilocid", "Tribimol", "Vikair".
If it causes side effects or if Ulcavis is not suitable for some other reason, the instruction on the use of analogues recommends careful selection and only after consultation with the doctor. After all, only a doctor, assessing the patient's health, will help to make the right choice.
The drug "De-Nol" is the most expensive and popular analogue of the drug "Ulkavis".The instruction of "De-Nol" fully describes the principle of the action of tablets, as well as the way they are used. Just like the previous preparation, "De-Nol" contains bismuth tricalium dicitrate. The medicine protects the gastric mucosa from damage, restores it. Another drug reduces the activity of peptin( a gastric enzyme) and stimulates blood circulation in the mucous membrane.
The drug has antibacterial activity against the bacterium Helicobacter pylori, which often provokes the appearance of gastritis and ulcers. It is well soluble, as a result of which it is able to penetrate deep into the mucous layers of the stomach.
The drug should not be taken by children, as well as pregnant and lactating women. Therapeutic course lasts 1-2 months. Adults per day should consume four tablets.
Produced in the Netherlands by the company "Astellas".The cost of 8 tablets - about 60 rubles, 56 dragees - 450-500, 112 pills - 800-850 rubles.
The patients' reviews call "De-Nol" the best antiulcer. It is noted that the drug acts quickly and effectively, and the improvements are noticeable after several days of using the tablets. The drug is well tolerated by patients and rarely causes side effects. It is used in complex therapy in the treatment of Helicobacter pylori. Some patients consider the price of the medicine too high, so often pay attention to its counterparts.
Novobismol is a Russian analogue of Ulkavis.
. Novobismall tablets are a Russian analogue of Ulkavis. The drug is recommended for use in ulcers and gastritis, which are caused by the bacterium Helicobacter pylori. Usually the medication is prescribed during the period of exacerbation of these diseases. Another indication for the use of tablets is irritable bowel syndrome, which is accompanied by diarrhea, and functional dyspepsia.
The drug is indicated for adults and children from four years in a dose of two to four tablets per day. The course of treatment lasts about 1-2 months. If improperly taken, it can cause side effects. The drug is not recommended to take more than eight weeks. When it is used, it is possible to stain the stool and tongue black.
The drug is manufactured by PharmProject. The cost of 56 tablets - 300 rubles, and 120 - 600 rubles.
Patients note the effectiveness of this tool. They say that it rarely provokes the appearance of negative reactions. Can be used in conjunction with other medicines for the treatment of diseases caused by the bacterium Helicobacter pylori. The drug quickly removes symptoms in ulcers and gastritis. It is simple in application. It is not sold in every pharmacy - this is, perhaps, its main drawback. Patients do not notice any negative phenomena when using medication.
Cheap substitute "Vikair"
The "Ulkavis" medication is recommended for use only by the doctor's prescription."Vikair" is the cheapest analog of this drug. Is a combined medicine. In its composition, in addition to bismuth nitrate, there is magnesium carbonate, sodium hydrogen carbonate, as well as the rhizome of ayr and buckthorn bark. The medicine has astringent, laxative, antispasmodic and antacid properties.
Tablets are prescribed for gastric ulcer and duodenal ulcer. Effective medicine for gastritis. The drug is taken 1-2 tablets three times a day. Therapeutic course lasts 1-2 months.
The drug is produced in Russia by the companies "Dalhimpharm", "Pharmstandard-Tomsk" and "Pharmstandard".The cost of 10 tablets is 25-30 rubles.
Reviews note that the medicine relieves pain with gastritis and ulcers on the third day of use, and on the 7-10th day the improvements become so obvious that a person completely forgets about the disease. The drug is weak, so it does not fit people who are prone to diarrhea. Some patients noted an increase in appetite after taking the pills and a violation of the digestive process. In general, this medicine has proved itself well and can replace tablets "Ulkavis" if necessary.