Preparation "Betaxolol": instructions for use, description, composition and reviews

Eye drops "Betaxolol"( instructions for use refer to them for selective long-acting beta-blockers) are actively used in ophthalmic practice, and tablets are widely used in the treatment of a number of cardiovascular diseases.

Form release and composition

The agent "Betaxolol" is available in the form of tablets and eye drops. One white film-coated tablet contains 20 mg of the active ingredient of betaxolol hydrochloride. As additional ingredients are: sodium carboxymethyl starch, magnesium stearate, microcrystalline cellulose, lactose monohydrate, aerosil. The composition of the shell contains: polyvinyl alcohol, white opadray-2, macrogol, talc, titanium dioxide.

Packed in 10 pieces in aluminum blisters pills "Betaxolol".The instruction for use is enclosed in a cardboard box.

In eye drops per 1 ml, 5.6 mg of the active ingredient of betaxolol hydrochloride. Secondary substances in the drug are sodium hydroxide, benzethonium chloride, hydrochloric acid, disodium edetate dihydrate, sodium chloride, water. It is a yellowish transparent substance. The solution is enclosed in a vial-dropper( 5 or 10 ml).It is also available and a tube-dropper with a dosage of 1.5-5 ml. In the cardboard box, insert the instruction and the vial-dropper.

Shelf life and shelf life

Shelf life of drugs( tablets and eye drops) is three years. After opening the drops, the vial can be stored for no more than twenty-eight days.

Pharmacokinetics

Pharmacological action of the drug is characterized by beta-adrenergic blocking selective, antianginal, antihypertensive, antiarrhythmic, antiglaucomal.

Blocks beta1-adrenergic receptors, has no sympathomimetic activity, and is also released by small membrane-stabilizing properties. Reduces the susceptibility of tissues to catecholamines, slows down central impulses, stops the secretion of renin. Reduces the degree of heart rate and reduces oxygen consumption by myocardium( antianginal properties).It blocks emerging ectopic foci in atria, AV combinations.

The result is observed two hours after admission, and the maximum concentration of the drug in the body is fixed after 3-4 hours and lasts for 12-24 hours, it normalizes with constant use of the drug for 7-14 days. Protects against increased blood pressure during physical exertion and psychological stress.

Treatment of high blood pressure occurs due to a decrease in the mass of the myocardium of the left ventricle and increase its contractile function. About 75% of patients with mild or moderate hypertension respond well to such a monotherapy. Long-term use of the drug does not affect the standards of lipid metabolism and sodium excretion. People with asthma and bronchitis in chronic form do not reduce the function of external respiration.

Eye drops "Betaxolol"( instructions for use indicate the effect of the drug on reducing the intraocular pressure by reducing the intraocular fluid) do not cause such side effects as hemorrhagia, miosis, accommodation spasm and blurred vision.

The effect is achieved after half an hour after the application, the maximum concentration is observed after two hours and lasts for twelve hours.

Indications for use

It is recommended to take the diagnosis of "arterial hypertension", a transient attack of myocardial ischemia( angina pectoris), akathisia provoked by neuroleptics, tablets "Betaxolol".

Eye drops( instructions for use advise you to consult a doctor before using them) are indicated in case of open-angle glaucoma, intraocular hypertension. Doctors prescribe the drug after laser trabeculoplasty. Used for prolonged antihypertensive therapy, the need for which has arisen because of surgical ophthalmologic intervention.

Medical contraindications

Despite the proven effectiveness of the drug "Betaxolol"( the instruction on the use of the drug advises to strictly observe the doses prescribed by the doctor and not engage in self-medication), its use has certain contraindications. These include hypersensitivity to the active component of the drug and additional substances in its composition. It is also forbidden if the sinus bradycardia( less than 45-50 bpm) and the weakness of the sinus node are fixed. You can not use the medicine in AV block II-III degrees, arterial hypotension. Contraindicated "Betaxolol" people with cardiogenic shock, patients with severe heart failure and severe obstructive respiratory failure.

Caution should be taken with chronic pneumonia, patients with unstable angina, a predisposition to bradycardia. Alertness should cause an AV block of the I degree, peripheral circulation failures. Particular attention should be paid to patients with diabetes, hypoglycemia, liver and kidney disease, hyperthyroidism. Doctors should monitor the medication in patients with muscle weakness, in the elderly and children.

During pregnancy and lactation, the medication is taken if the expected benefit to the mother exceeds the potential risk to the fetus. For the duration of therapy, stop breastfeeding.

"Betaxolol": instructions for use

Price, testimonials, composition - these are the positive aspects of the drug, which cause patients to choose again and again.

Tablets should be taken in the morning. When hypertension, dragees are taken once, starting with a dose of 10 mg. If after a week the desired effect is not obtained, then the dose is raised to 20 ml. If the expected result was not achieved again, then after 7-14 days the dose is increased to 40 mg.

Patients with impaired renal function receiving dialysis, as well as elderly people should consume 5 mg once. If necessary, the dose can be increased every 14 days by 5 mg. It recommends not to exceed the maximum dose - 20 ml of the preparation "Betaxolol" - instructions for use.

Abstract advises to use eye drops for glaucoma. Instillation should be carried out strictly in a conjunctival sac. A single dose equals one drop. This event is held twice a day. During the first month of treatment, the physician should monitor the intraocular pressure of the patient.

Side effects of

Claims that the use of the preparation "Betaxolol", instructions for use may lead to side effects. The price of the medication is democratic, which makes it affordable for all segments of the population( 80 rubles per bottle 5 ml and 370 rubles for 30 tablets).

In the process of treatment, "Betaxolol" can cause chronic fatigue and headache, dizziness, drowsiness, sleep disturbance, anxiety, depressive conditions. The concentration of attention decreases, nightmares, hallucinations, amnesia, neuralgia, vestibular disorders.

Some patients have seen impotence and micturition, chest pain( in women), prostatitis, fibrocystic changes. There was a digestive disorder, diarrhea, dry mouth, nausea, vomiting, constipation, abdominal pain. The drug sometimes adversely affects infectious lung diseases, dyspnea, causes pain in the chest, pharyngitis, rhinitis, sinusitis. Cramps of bronchi, shortness of breath, respiratory failure were recorded.

Among the side effects were the following: bradycardia, hypotension, myocardial infarction, heart failure, leukocytosis, thrombocytopenia, purpura and other diseases. Arthralgia, tendonitis, myalgia were rare.

There may be rash, alopecia, allergic reactions, eczema, weight change, erythema, hypothermia, exacerbation of psoriasis, hypertrichosis, prurigo.

The use of eye drops can provoke lacrimation, dry eyes, blurred vision, photophobia, keratitis, erythema, foreign body sensation in the eye, corneal sensitivity, anisocoria and photophobia.

Special instructions

When treating with Betaxolol( instructions for use details the dose and method of treatment), often a change in the indicators of laboratory tests. This can be a false positive reaction to doping, an increase in the titer of antinuclear antibodies, etc.

Overdose of the preparation "Betaxolol"

Instruction for use( analogues have the same active substance and have a similar effect) strongly recommends compliance with the dosage. Otherwise, you may encounter such unpleasant symptoms:

• dizziness;
• disruption of the cardiovascular system;
• bronchospasm;
• decrease in blood glucose;
• muscle cramps;
• collapse.

In this case, a classic treatment is prescribed according to the following scheme:

• gastric lavage;
• the use of adsorbent substances;
• symptomatic therapy - atropine intravenously 1-2 mg, beta-adrenomimetics, sedatives, cardiotonic drugs;
• transvenous stimulation( prescribed only in case of emergency).

About precautions

Therapy should only be carried out under medical supervision. During the treatment, you can not notice the initial stage of thyrotoxicosis and hypoglycemia. This is especially true for patients with diabetes mellitus. Reduced compensatory processes of the heart and blood vessels. Do not use the drug before surgery.

Regular use of medication by elderly people increases the likelihood of hypothermia, unstable mental state, and cardiovascular disorders. Patients with kidney and liver disease should be supervised by the doctor for the first four days. With an allergic history, there is a possibility of increasing hypersensitivity and reducing the therapeutic effect of adrenaline.

Do not drink alcohol when taking this medication. Also, you can not abruptly stop therapy, but you need to do this slowly, by reducing the dose within two weeks. Advises caution to drivers when using the drug "Betaxolol" instructions for use.

Price, analogues of the preparation

If the drug is not approached, the attending physician can always offer an analog, which often differs only in price. Thus, tablets and drops of Betaxolol cost about 80-370 rubles. Analogues of tablets include:

• "Betak"( Cyprus), costs about 300 rubles for 20 tablets.
• "Lokren"( France), the price for 28 tablets - 600-700 rubles, and for 56 pills - 1000-1200 rubles.

Eye drops with active ingredient Betaxolol hydrochloride can be replaced by the following drugs:

• "Betalmik EU"( Slovakia), 160-200 rubles.
• "Betoptik"( Belgium, USA), about 300 rubles.
• "Betoptik S"( Belgium, USA), within the limits of 300 rubles.
• "Betofant"( Romania), 200 rubles.
• "Xonef"( India), 180 rubles.
• "Xonef BK"( India), about 150 rubles.
• "Optibetol"( Poland).

Speaks about the effectiveness of treatment of hypertension with the drug Betaxolol instruction manual. Price, reviews( analogues are more expensive, and the impact on the body is the same) - all this information is presented in the article.

Opinions of patients

Recommends the use of "Betaxolol" drops in ophthalmic therapy. The price( reviews say this is one of the benefits of the drug) is low, and therefore almost anyone who needs treatment can buy them. Many patients emphasize the good tolerability of eye drops. They say that they do not cause side effects. The result is visible by the end of the first week.

With the help of tablets, people control blood pressure. The drug helps reduce the burden on the heart, improves the overall condition of patients. Some emphasize the frustration of the digestive process in the first days of taking the tablets. There are people who have caused the drug to cause allergies, rashes and redness on the skin. Someone observes nausea and severe arrhythmia.

Most of the reviews about the drug are positive, the patients were satisfied with this therapy.