The drug "Colofort": reviews of doctors, instructions for use, composition, prices. Analogues of "Koloforta"
Spasmolytic is called a drug that helps suppress muscle spasms. As you know, such drugs are very often used to eliminate pain and other unpleasant sensations in the digestive system. Also it should be said that these medications are often prescribed for diseases of the urinary system.
What antispasmodics are known to you? The most popular remedy with such properties is the preparation "Colofort".Instructions for use, price, doctor's comments, analogues and features of this medication are indicated below.
Composition of the medicinal preparation, its packaging, form of release and description
In what form are the preparations made "Kolofort"?Reviews of doctors say that this drug can be purchased in any pharmacy in the form of tablets for resorption.
This medication is white, chamfered, at risk, flat-cylindrical.
What ingredients does the "Coloform" contain? The doctors' comments indicate that the active components of the drug in question are affinity purified antibodies to:
- to human TNF-alpha;
- to the brain-specific protein S-100.
It should also be noted that as additional components this preparation contains MCC, lactose monohydrate and magnesium stearate.
This medicine is sold in contour cells, which are packaged in carton packs.
The main properties of the drug
What is remarkable about the drug Koloforl? Instruction, reviews( the price of the drug is listed below) report that this medication has anti-inflammatory, anxiolytic and antispasmodic properties.
According to experts, the active components of this agent are able to modify the activity of ligand-receptor interaction of endogenous regulators with the corresponding receptors( in particular, antibodies to S-100 proteins to serotonin and sigma-1 receptors, antibodies to TNF-alpha to TNF receptors-alpha, antibodies to histamine - to histamine H4-receptors, which are located in the digestive tract).
Combination of the listed active ingredients of the drug allows complex effects on the central as well as peripheral links of functional disorders of the intestinal tract, including abdominal pain.
Features of the drug
What is remarkable about the medicine "Koloftort"?Reviews, instructions( the price of this medication is quite high) argue that the effectiveness of the drug in question is due to its components.
Antibodies to S-100 proteins have a wide psychotropic activity. They also have nootropic, anxiolytic, antidepressant and anti-asthenic actions. This is manifested in the elimination of internal tension and anxiety. In addition, this component normalizes a number of visceral functions, including the work of the large intestine. It should also be noted that antibodies to S-100 proteins do not cause withdrawal syndrome( including addiction) and do not have a sedative effect.
Antibodies to histamine have anti-edematous, anti-inflammatory and antispasmodic effects.
Antibodies to TNF-alpha have a pronounced anti-inflammatory effect. In addition, they contribute to the normalization of the balance of proinflammatory cytokines.
Principle of operation of
How does the preparation "Koloforth" work? The doctors' comments report that the combination of the listed components of the drug reduces visceral hypersensitivity of the receptors, and also normalizes the humoral and nervous regulation of the intestine.
One can not help saying that this drug eliminates abdominal distention, promotes the restoration of impaired motility of the gastrointestinal tract, reduces the severity of abdominal pain and eliminates the feeling of fullness of the stomach.
As for the spasmolytic effect of this medication, it manifests itself in a decrease in the tone of the gastrointestinal wall, normalization of the stool, relaxation of smooth muscles and a decrease in intraluminal pressure.
Indications for taking
When should I take the "Coloform" preparation? The doctors say that such tablets for resorption work well in the treatment of IBS, that is, irritable bowel syndrome. It should also be said that this remedy can be used for general functional disorders of the digestive system.
The medicament in question has practically no contraindications. It can not be taken only if there is hypersensitivity to its elements.
How to use the medicine
The absorbable tablets "Colofort" should be taken only inside, long before the meal.
A single dose of this medication is one or two tablets twice a day. The medicine should be kept in the mouth until it dissolves completely.
The course of treatment with such a drug is from one to two months. If necessary, the therapy can be extended to six months or repeated 60 days later.
In case of aggravation of diseases of the digestive tract, the frequency of intake of the drug should be increased to four times a day for up to two weeks.
Adverse effects of
Does the drug in question cause adverse reactions? What do consumers say about this( about "Kolofort")?Analogues of the drug and the very mentioned remedy are transferred by the patients quite well. Only sometimes, against the background of their reception, hypersensitivity reactions can develop.
Recommendations for taking the medicine
According to the instructions, the composition of the drug in question includes lactose. Therefore, it can not be administered to people with congenital galactosemia and lactase deficiency, as well as malabsorption syndrome of glucose or galactose.
It should also be noted that this drug does not affect the patient's ability to manage dangerous machinery or vehicles.
Analogues and cost of medicine
The cost of this drug is approximately 400-430 rubles per 100 absorbable tablets.
This tool can be replaced with Pepsan-R, Antiflat Lannacher, Bobotik, Plantex, Bebinos, Disfatil, Gascon Drop, Gastrokapom, Dicetelom, Iberogastom, Meteospazmilom "," Sab Simplexom. "
"Colofort" preparation: reviews
The real opinions of doctors about this remedy are positive. According to the statements of experienced specialists, this medication is effective in irritable bowel syndrome.
As a rule, after the passed course of treatment with this drug, patients completely normalize the stool. Also, all the unpleasant sensations associated with the said intestinal disease disappear in patients.