"Cefix"( suspension): instruction for children, description, composition and reviews
"Cefix" - suspension( instruction for children comes with a product), the active ingredient of which is cephalosporin of the 3rd generation. This antibiotic effectively cures not only diseases of the respiratory system, but also other infectious ailments. The medication is also available in the form of capsules.
Composition and form of release
"Cefix"( instruction, use, composition of this preparation indicate its effective effect on the children's organism for colds, acute respiratory viral infections, angina, influenza, etc.) contains the active substance ceficim trihydrate. At 5 milliliters of the suspension, 100 mg of the active ingredient is necessary. Additional ingredients are croscarmellose sodium, sodium carboxymethylcellulose, xanthan gum, microcrystalline cellulose, sodium benzoate, citric acid monohydrate, flavor, sucrose.
Auxiliary components of the capsules are magnesium stearate, sodium lauryl sulfate, vegetable hydrogenated oil, croscarmellose sodium, microcrystalline cellulose.
Suspension for oral administration is given in a dosage of 100 mg / 5 ml in a 30 ml bottle and 100 mg / 5 ml in a 60 ml bottle. Capsules contain 200 and 400 mg of active ingredient.
The prepared suspension should be stored in a cool place for no more than fourteen days. The preparation in the form of capsules is stored at a temperature not exceeding + 25 ° C.Shelf life of undiluted suspension and capsules is about three years.
Pharmacology of the drug
"Cefix" is a suspension( the instruction for children fully describes the correct use of the drug), which has a high stability to the presence of beta-lactamase enzymes, which are aimed at combating beta-lactam antibiotics. As a result, organisms resistant to penicillins and cephalosporins may be susceptible to the effects of the active substance of the drug.
"Cefix" is a broad-spectrum antibiotic and affects most strains of microorganisms, among which are:
- Gram-positive are pneumococcus, pyrrolidonylpeptidase, Streptococcus.
- Gram-negative, such as Proteus Mirabilis, Haemophilus Infections, Moraxella( Branhamella) catarrhalis, Escherichia coli, Gonococcus.
"Cefix" is instantly absorbed in the gastrointestinal tract. The speed of this process is not affected by eating. Bioavailability for adults and children is about 30-50%.The greatest concentration of the active substance is achieved after 2-6 hours after taking the drug inside, regardless of its form of release. About half of the dose taken within a day is excreted in the urine unchanged. Part of cefixime trihydrate comes out with bile.
With moderate impairment of kidney function, 50% of the active substance leaves the human body to 6.4 hours. With a severe degree of renal failure, the half-life is 11.5 hours.
Indications for use
"Cefix" is a suspension( the instruction for children does not recommend using it without consulting a doctor), which is often prescribed for various infectious diseases of the urinary tract. Indication for use is the acute form of intestinal diseases. An antibiotic is prescribed to treat a number of diseases caused by pneumococci and streptococci pyrrolidonyl peptidase. Apply medication for ENT diseases, such as pharyngitis, tonsillitis, otitis and sinusitis. It is used for various forms of bronchitis, acute pneumonia and other infectious diseases of the respiratory tract.
Completely contraindicated for people who are allergic to antibiotics of the cephalosporin series, the drug "Cefix"( suspension).Instruction for children( reviews of some women note that the improvement after taking the medication comes on the 2-3rd day of its use) until the age of twelve forbids the medication in capsules. For the treatment of children from six months to twelve years, a suspension should be used. You can not take the medicine to pregnant and lactating women, if the expected positive effect for the mother is several times greater than the risk of fetal pathology, then the doctor allows the use.
"Cefix": instructions for use for children
Suspension, unlike pills, is allowed for use by young children. Drink after fifteen minutes after eating.
For children of the age group of twelve years and adults, the maximum daily dose of the drug is 400 mg. Duration of admission is controlled by a physician. This period depends on the age and severity of the disease. Patients with a creatinine clearance of 21 and 60 mL / min are reduced to 300 mg per day. Patients with a creatinine clearance less than 20 ml / min dose reduced to 200 mg per day.
Children from six months to twelve are assigned another form of the drug "Cefix" - a suspension. Instruction for children how to plant the powder on their own, tells in detail. To do this, take 30-35 ml of boiled water not below +25 ° C and pour the liquid into a vial of powder, close and carefully shake all the contents. After this process, the bottle is opened and water is added to the risks. After that, the lid is twisted again, and the components are thoroughly mixed.
You can drink "Cefix" both before meals and after. If the antibiotic caused irritation of the mucosa of the gastrointestinal tract, then it is used during meals.
The dose of the suspension is determined based on the age and weight of the child. So, children from six months to twelve are advised to take 8 mg per kilogram of weight. The recommended volume can be divided into several receptions, or the entire volume can be drunk at a time.
For children from 12 years old, having a body weight of 50 kg or more, an adult dosage is prescribed, which can reach 400 mg per day. The course of treatment is determined by the course of the disease.
Side effects of the drug "Cefix"
Instruction( the description of the drug warns about the importance of compliance with all recommendations) indicates that the drug can cause a number of side effects, they can include:
- diarrhea, nausea and pain in the abdomen;
- dyspepsia, colitis and flatulence;
- various rashes on the skin( rash, itching and hives);
- malfunctions in the lymphatic system;
- allergic reaction and serum sickness;
- dry mouth and general weakness;
- dysfunction of the kidneys;
- fungal infections of female genital organs;
- dizziness, fatigue and headache;
- excessive sweating, baldness and epidermal necrolysis( dying of the upper layer of the skin).
In some cases, an overdose was observed, which manifested itself in the form of diarrhea, dizziness, nausea and vomiting. If such a symptom is found, you should rinse the stomach, take antihistamines, and do oxygen therapy.
Interactions with other drugs
Nephrotoxicity of the drug increases if it is used simultaneously with "Furosemide" and aminoglycosides.
The duration of the prothrombin period with manifestations of bleeding or without them increases with the use of "Cefix" with anticoagulants.
It is forbidden to drink alcoholic and tonic drinks during therapeutic treatment.
Analogues of the drug
Not once proved its effectiveness in the fight against infectious diseases "Cefix"( suspension for children).The instruction( the price for this drug is quite high) describes in detail all the methods of treatment, as well as indications and contraindications. If this tool does not work, you can always choose a suitable analog. According to the content of the active substance and the form of release, the medicine is similar to such medicines:
The above preparations are produced in the form of a powder for the preparation of a suspension and are suitable for children. Capsular analogues include "Supraks Comfortab", "Supraks Solutab", "Loprax" and "Flamifix".
These drugs can completely replace the "Cefix"( suspension for children).The instruction( the price can vary slightly depending on the mark-up on the sales network) warns that before using this antibiotic, you should consult a doctor.
This is a new drug that has gained popularity relatively recently. Despite this, you can find it in every pharmacy. The cost of the tool fluctuates around 900 rubles. It can slightly change in the direction of decreasing or increasing the price of the drug "Cefix".Instructions for use, description, reviews of mothers talk about the effectiveness of this tool in the treatment of angina and other diseases, so the medicine is worth this money.
Reviews about the
"Cefix" - a suspension( the instruction for children warns that before taking the medication you should read the contraindications), about which there are many positive opinions. Women note the effectiveness of the drug. They say that the improvement in the child's condition came on the second day of his admission. The throat has ceased to hurt, the cough has disappeared, fatigue and other signs of a cold have passed. It is claimed that the remedy has a wide spectrum of action and thus helps cure angina, tracheitis and infectious diseases of the intestine. Not once proved its effectiveness in the treatment of diseases of the upper respiratory tract, where it acted quickly and efficiently. I like children, because it has a bright and delicate taste of strawberries.
Among the shortcomings of the medication, the reviews highlight an allergic reaction, a high cost and a short shelf life of the diluted suspension. Women say that for a child aged 10-12 years, you need to buy two bottles, since one is not enough for a full course of treatment. A certain part of people did not see any effect after using this medication and considers its use useless.
"Cefix" is an antimicrobial agent that quickly cures pulmonary and other infectious diseases. Rarely causes side effects. It differs from others in its effectiveness.