Cholecalciferol: instructions for use, indications, dosage

The lack of vitamin D has recently been encountered more often. People have become less on the street, eating healthy food. This leads to fragility of bones, hair, nails, deterioration of appearance and well-being. In many individuals with chronic fatigue syndrome and oncological diseases, laboratory tests reveal a deficiency of an important substance. Excess is not less dangerous, therefore, a doctor must decide whether to take it.

General characteristics of

Vitamin D is a generalized name for 5 varieties of substances. They have different origins, but they have an identical effect on the body.

Cholecalciferol( colcalcaliferol, vitamin D3) is a natural substance that enters the body together with food of animal origin or exposed to sunlight.

It is a white powder with a crystalline structure. Virtually does not dissolve in water, therefore belongs to the group of fat-soluble.

What is Vitamin D3 for? First of all, it ensures correct functioning of the musculoskeletal system, namely:

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• affects the absorption of calcium, phosphate and magnesium from the digestive tract;
• takes part in their exchange;
• helps to transport substances from the bloodstream into bone tissue;
• prevents softening of bones, the appearance of rickets and osteoporosis;
• allows damaged areas to fuse faster after fractures.

Additional functions include:

• strengthening of immunity, prevention of serious diseases, for example, oncology;
• increased elasticity of muscle tissue;
• prevention of skin and heart disease;
• maintenance of normal functioning of the thyroid gland;
• regulation of blood pressure;
• improvement of the brain.

The combination of cholecalciferol and calcium is often used to treat hypocalcemia and hypovitaminosis.

Symptoms of Vitamin D deficiency

In the early stages, a deficiency can manifest itself:

• is in a bad mood;
• lack of desire to do anything, sometimes even get out of bed;
• impairment of mental state( with propensity);
• metabolic disorders( obesity, diabetes mellitus);
• joint pain;
• deterioration of hair and nails.

Later joined:

• stoop;
• deformation of the skeleton;
• gait violation.

In men, a lack of vitamin leads to a decrease in sperm activity and infertility.

Who is appointed?

According to the instructions for the use of cholecalciferol, it is necessary for the following pathologies:

• rickets( bone formation disorder and skeletal mineralization disorder);
• osteoporosis( softening of the elements of the musculoskeletal system);
• spasmophilia and hypocalcemic titania( pathologies that occur against the background of hypocalcemia of the blood accompanied by convulsions);
• of nephrogenic osteopathy( skeletal lesion on the background of calcium-phosphorus metabolism disturbance);
• reception of anticonvulsants and barbiturates;
• hypophosphatemia( reduced serum phosphate levels);
• brittle nails, hair;
• dental problems.

And also with disorders in the digestive system:

• of Crohn's disease;
• sharp weight loss;
• syndrome of malabsorption( impaired absorption in the intestine).

Additional indications for cholecalciferol are as follows:

• cirrhosis;
• mechanical jaundice;
• dependence on alcohol;
• hepatic failure.

Recommended:

• for pregnant and lactating mothers;
• to people who are on strict diets, vegetarians, patients receiving parenteral nutrition;
• for young children( newborns, infants in the autumn-winter period).

The basis for taking medication can be any condition that arose against a background of deficiency of colcalciferol.

Contraindications and possible side effects of

The agent is not used in conditions such as:

• individual intolerance;
• increased content of vitamin D and calcium in the blood;
• renal osteodystrophy amid a rise in serum phosphate.

With the use of an additive strictly according to indications, the deterioration of well-being is rarely observed. Patients present the following complaints:

• development of skin allergic rashes;
• increase in blood pressure;
• exacerbation of pulmonary tuberculosis;
• headaches;
• detection in hypercalcemia, hypercalciuria;
• appearance of arthralgia, myalgia;
• cardiac rhythm disturbance;
• impaired kidney function.

Overdose

The administration of colcalciferol in high doses leads to an increase in side effects.

Additional symptoms of overdose include:

• aversion to food, severe weight loss;
• of urine when urinating, frequent urge to go to the toilet;
• strong constipation.

Symptomatic therapy is performed by corticosteroids, thiamine, retinol, magnesium, potassium, vitamins C and E, pantothenic acid.

Prolonged intake of high doses leads to problems of a different plan:

• deposition of salts in the kidneys, heart, lungs and other internal organs;
• demineralization of bones;
• to death.

Heavy lesions do not respond to treatment.

Drug Interaction

In accordance with the instructions for use for cholecalciferol, the concentration of the substance in the blood reduces:

• mineral oils;
• calcitonin;
• gallium nitrate;
• plikamycin;
• derivatives of etidronic and pamidronic acids;
• colestramine;
• Colestipol.

Simultaneous reception with phosphorus-containing agents leads to increased absorption of the latter.

If it is necessary to use tetracycline during the treatment period, it is necessary to do an interval of 3 hours, sodium fluoride - 2 hours.

During the course of treatment, do not use other supplements containing colcalciferol. So the risk of developing hypervitaminosis rises.

Special instructions

Treatment of hypovitaminosis should be performed on the recommendation of a physician with periodic monitoring of calcium in the urine.

The daily norm for an adult is 400 IU.Regular excess of dosages leads to chronic hypervitaminosis and worsening of well-being.

Pediatricians often recommend giving children cholecalciferol for the prevention or treatment of rickets during the cold season. It should be borne in mind that for 12 months the baby should receive no more than 10 - 15 mg.

High doses of substances taken by a future mother have a toxic effect on the embryo. This is fraught with:

• mental retardation;
• deformation of the skull;
• worsening parathyroid function;
• by stenosis of the aorta;
• development of high sensitivity to colcalciferol.

It is dangerous to exceed the recommended doses 4 to 15 times for a long time.

In older people, the substance is digested worse, so they often need additional medications.

Dosage for adults and children

How many drops should a patient drink, the doctor decides, based on the results of tests, general condition, age and sex, and other characteristics.

Instructions for use for cholecalciferol are included for informational purposes.

Water drops are taken in a pure form or diluted with any non-hot liquid. An oily solution is always bred.

On an average, oral administration of 400 to 600 IU per day. Intramuscularly - 200 thousand IU.

Treatment of rickets with the help of injections is carried out once a week for 200 thousand IU, in addition, calcium salts are used. The minimum course of admission is 2 weeks.

For the treatment of osteoporosis, the same dosage is administered every 2 weeks for 3 months.

Once a day, 1 million IU is prescribed to prevent seizures.

With hypoparathyroidism, the maximum dose is 15,000 IU.

Spasmophilia in infants is treated - 5000 IU three times a day.

To prevent osteomalacia take 3 times a day 500-1000 IU, for therapeutic purposes - 2500 IU.

Analogues

The price of cholecalciferol can vary significantly and depends on the form of release and the manufacturer.

The most popular water drops are "Aquadertrim" of Polish origin. They have a transparent color, slightly smell of anise.

1 bottle contains 10 ml of colcalciferol with an activity of 15 000 IU.Approximate cost is 300-400 rubles.

No less popular is the German "Wigantol".This oil droplets with an activity of 20 000 IU.It is taken orally in a diluted form( in milk or other liquid).The average price per bottle 10 ml - about 400 p.

Колекальциферон is present in structure of many complex vitamins in the form of usual and chewing tablets. For example, "Calcium D3 Nycomed".

Dosage and costs may vary significantly.

There are no cheap drops on the basis of colcalciferol. In the pharmacy you can buy a budget "Ergocalciferol" in the form of an oily solution, but its active ingredient is vitamin D2, so the expediency of such a replacement should be clarified by the doctor.

Detailed instructions for use on cholecalciferol can be found in the box with the product to be purchased.

Forms and conditions of dispensing from pharmacies

The drug is sold as solutions for intramuscular administration and oral administration. Or as a drop inside.

It is released by prescription, but in practice it can be purchased by anyone.

The vials are kept in a cool place, protected from sunlight.

Shelf life - 2 years from the date of issue. The spoiled drug should be discarded.

Reviews

You can hear a lot of good and bad about cholecalciferol.

All doctors agree that taking the indications often gives a positive effect. The exception is rare forms of individual intolerance of additional components of the drug. In this case, the facility is canceled and another is assigned.

Individuals have increased sensitivity to cholecalciferol. At them the recommended quantity of a medicine can cause deterioration of state of health, namely symptoms, characteristic for acceptance of high doses. In such patients, the amount of the drug is lowered.

Do I need to take vitamin cholecalciferol to newborns and young children - a controversial issue, but most pediatricians believe that yes. In their opinion, rickets are easier to prevent than to deal with its consequences.

Individual experts insist that with a balanced feeding of a nursing mother or baby and sufficient stay on the street, additional medication is not required.

Patients often say that drugs based on cholecalciferol cause skin allergic reactions, regardless of the manufacturer's firm. In general, the problem is observed in young children. Doctors are sure that often the supplement has nothing to do with the rash, and mothers should reconsider the child's diet.

Parents still insist on their rightness and argue that all the defects were after the drug was canceled.

People very much praise chewable tablets "Calcium D3 Nycomed".They allow you to quickly cope with the fragility of nails and hair, stop the destruction of teeth.

Preparations based on cholecalciferol excel at their main purpose - treatment of diseases associated with its deficiency. Patients who took vitamin D3 according to the indications consider the drug effective. Information is confirmed by laboratory tests.

Uncontrolled intake of supplements on the advice of friends and relatives often leads to overdose, hypervitaminosis. Most often people complain about the appearance of urolithiasis and cholelithiasis, disruption of the bowels, heart and other organs.

According to doctors, it is necessary to check for a deficiency of the following:

• pregnant and lactating women;
• for premature and often ill children;
• for patients with HCC;
• to people who are exhausted by diets;
• persons who are rarely in the sun.

Healthy people can avoid shortages, eating properly and regularly on the street.

In the initial stages, vitamin D deficiency is easily replenished with solutions and tablets of cholecalciferol. Do not buy and drink by yourself, adhering to your own beliefs. It is important not only to establish the fact of the deficit, but also to find out its cause. Thoughtless use of the drug leads to severe consequences and even death.