"Amlodipine": what helps, instructions for use, analogues, reviews

What is hypertension? Many people know the answer to this question, especially the elderly. As is known, this is a persistent increase in blood pressure, in which such indicators as 150/90 mm Hg are noted. Art.and higher. Amlodipine from what helps

It is generally accepted that hypertension is the most common cardiovascular disease. A persistent increase in blood pressure is observed in 25-30% of the adult population. By the way, with age, this disease is noted in 55-65% of people.

Why arterial hypertension occurs? This phenomenon can develop due to a variety of reasons. Most often in elderly people, the pressure rises due to psychoemotional overstrain. Therefore, people prone to hypertension should be as calm as possible.

One can not help saying that such a disease often arises from a sedentary lifestyle, age, sex( more often in representatives of the weaker half of humanity), excessive consumption of table salt, hypocalcemia diet, alcohol abuse, heredity, obesity, smoking, diabetes mellitusetc.

Is it necessary to treat arterial hypertension? Doctors say that if you feel unwell, the patient should definitely take drugs that lower blood pressure. To one of them carry such a medicine as "Amlodipine".Side effects of this tool, its features, cost and analogues are indicated below.

Description of the medicinal product, its composition and packaging

In what form are the medicines "Amlodipine" manufactured, the price of which is given below? The drug in question is produced in the form of white tablets and a flat-cylindrical form. Its active ingredient is amlodipine.

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This drug is sold in contour cells( 10 tablets), which are packaged in cardboard packages.

Mechanism of action of drug

What is good about Amlodipine? According to the instruction, this drug shows pronounced antihypertensive and antianginal properties. In addition, it does not allow calcium ions to penetrate membranes into vascular cells and myocardial cells.

What is the drug "Amlodipine"?What helps this medicine? It well reduces high blood pressure. This is due to the ability of the drug to dilate the blood vessels.

It should also be noted that the drug in question has an antianginal effect. This property of the drug is provided by its active element. Doctors report that amlodipine not only expands arterioles( peripheral), but also reduces OPSS.This ingredient does not cause tachycardia( reflex).

What is the result of using the drug "Amlodipine"?What helps this tool? Thanks to such a preparation, the human heart begins to consume much less energy and the need for myocardium in oxygen significantly decreases.

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Kinetic features of the drug

The drug "Amlodipine" from the pressure( increased) is absorbed from the intestine very slowly, but in its entirety. The peak concentration of its active component in the blood is reached after 8.5 hours. The binding of the drug to plasma proteins is approximately 98%.

The drug "Amlodipine", whose action is aimed at lowering the pressure, undergoes minimal metabolism. In this case, derivatives are formed that have little pharmacological activity. The drug is metabolized when passing through the liver.

The average half-life of amlodipine and its derivatives is 36 hours. With a very high blood pressure, this time can be increased to two days, in elderly people - up to 66 hours, and with liver dysfunction - up to 58 hours.

Drug is given in the form of metabolites through the intestine and kidneys.

The drug "Amlodipine": what helps?

In what cases can the medication in question be administered to a patient? Indications for receiving this remedy are the following conditions:

  • angina is stable;
  • vasoconstriction or vasospasm;
  • angina pectoris;
  • arterial hypertension( as a monotherapy and in combination with other medicines);
  • cardiomyopathy is a dilated non-ischemic one. amlodipine analogues price

In what other cases can the drug "Amlodipine" be recommended? What helps this medicine? It is often prescribed together with antianginal medicines, including patients who are immune to treatment with beta-blockers or nitrates.

Prohibitions for taking the drug

Now you know the purpose for which patients are prescribed "Amlodipine" tablets. The indications of this medication are listed above.

As for contraindications, the use of this medication is prohibited with arterial hypotension. In addition, it is not recommended to use at a minor age, as well as in the presence of hypersensitivity to its ingredients.

How should I take Amlodipine medication?

Analogues, the price of this medication is indicated below.

The agent is intended for oral administration. The dosage of this drug is calculated by the doctor, depending on the patient's condition.

For patients with hypertension( arterial) and angina pectoris, the minimum dose of this medication per day is 5 mg. If required, then in the future this amount can be increased exactly twice, that is, to bring up to 10 mg per day.

In the therapy of dilated cardiomyopathy, this medication is recommended to take in a dose of 2.5 mg. If the drug is well tolerated, its quantity can be increased fourfold.

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According to experts, exceeding recommended dosages of the drug( more than 10 mg per day) is highly discouraged, as this can lead to the development of undesirable effects.

Reception of "Amlodipine" together with beta-blockers, diuretics( thiazide) and ACE inhibitors does not require dosage adjustment.

Side effects of

How is the drug "Amlodipine" carried by patients? There are practically no side effects of this drug. However, in some cases( for example, with non-compliance with dosages), it can still cause:

  • tachycardia, gingival hyperplasia, flushing, drowsiness;
  • arrhythmia, nausea, palpitation, headache, dyspnea;
  • abdominal pain, peripheral edema, fatigue;
  • arterial hypotension, rash, paresthesia, itching, dizziness.

It should also be noted that with prolonged use of the tablets in question, the patient may experience pain in the limbs.

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Cases of drug overdose

There are no known cases of overdose with this medication. Although doctors suggest that when taking a large amount of the drug in patients can manifest severe side effects.

Drug Interaction

Is it permitted to take Amlodipine medication together with other drugs? Instruction, expert reviews argue that the hypotensive effect of this drug is enhanced if it is combined with calcium channel blockers. A similar result is expected when using funds intended for inhalation anesthesia and orlistat. By the way, such combinations can provoke even a hypertensive crisis.

Reduction of antihypertensive effect and sodium retention in the human body are observed with the reception of tablets "Amlodimin" with estrogens and sympathomimetics.

The development of neurotoxicity symptoms such as tinnitus, nausea, ataxia, vomiting and diarrhea is caused by the simultaneous administration of amlodipine and lithium carbonate.

Concurrent use of the drug in question and indomethacin, as well as other NSAIDs, leads to a reduction in the antihypertensive effect of the former.

Breastfeeding and pregnancy period

Safety of the drug "Amlodipine" during pregnancy has not been studied. The same applies to the lactation period. In this regard, the drug in such provisions should be used only if the risk to the child is much less useful for the health of the mother.

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General recommendations for taking the drug

The instruction, attached to the tablets, states that they should be taken with extreme caution in case of impaired liver and kidney function, as well as with stenosis of the aortic aorta.

The adjustment of the dose of the drug that was indicated above to the elderly is not required.

Medication "Amlodipine" can be used to treat patients with a diagnosis such as dilated cardiomyopathy( non-ischemic), which is accompanied by heart failure( chronic).

No clinical studies have been conducted on the use of this drug in pediatric practice.

Terms of Sale and Storage, Term of Implementation

Store this medication in a dark and dry place where the air temperature does not exceed 25 degrees, and where little children can not access.

This remedy is dispensed without a medical prescription. According to the instructions, the expiration date is 24 months. After this period, take the medicine is prohibited.

Cost of medicines in pharmacies and similar products

How much are the tablets "Amlodipine"?The price of this drug may be different, but in any case it is not very high. The drug in a dosage of 10 mg costs about 55 rubles, and in a dose of 5 mg - about 35 rubles. amlodipine action

As mentioned above, hypertension is a fairly common disease. Therefore, every year, pharmaceutical companies produce more and more drugs designed to lower high blood pressure. By the way, there are many analogs to the means under consideration. Doctors say that antihypertensive properties are characteristic for the following medicines: Agen, Tenox, Akridipin, Stamlo M, Adipin, Stamlo, Amlo, Normodipin, Amlodipine Sandoz, Omelar Cardio, Vero Amlodipine, Norvasc, Amlodipine Teva, Cordy Cor, Amlodak, Norvadin, Amlovas, Corvadil, Amlodigamma, Cardilopin, Amlodipine Alkaloid, Karmagip, Amlodil, Calchek, Amlodipine Zentiva, Amlonorm, Amlodipine-Agio, Amlotop, Amlodipine Cardio, Amrolus, Amlodipharm, AmlodipineBezilat, Amlong, AmLockard-Sanovel ", etc.

Reports from patients and doctors

With age, an increasing number of people are exposed to a disease such as hypertension. As is known, the following symptoms are typical for such a phenomenon: dizziness, excessive fatigue, headaches, weakness, darkening in the eyes, drowsiness and so on. According to experts, all these signs disappear within a few hours after using the tablet "Amlodipine" in a dosage of 5 or 10 mg.

Doctors report that the drug in question is one of the fastest and most effective means. Within a short period of time, it stabilizes the patient's blood pressure, and also significantly improves his general condition.

As for consumers, among the advantages of this tool, they note its convenient way of application and form. To reduce the increased pressure, the patient is required to take only one tablet. In this case, doctors warn that an overdose of this medicine may contribute to the occurrence or intensification of adverse reactions. In this regard, they do not recommend eating more than 10 mg of the drug per day. amlodipine

It should also be noted that a large number of consumers are pleased with the low price of the said product, as well as its availability in all pharmacies and the ability to replace with analogues.