Captopril: instructions, contraindications
One of the most effective and therefore common drugs for the treatment of hypertension is "Captopril".The instruction informs that it is an antihypertensive agent, which is recommended for treatment of:
- arterial hypertension;
- heart failure;
- Renovascular hypertension;
- myocardial infarction;
- for diabetic nephropathy.
This widespread use of the drug is associated with its ability to reduce the production of angiotensin II, which greatly narrows the blood vessels, increases the concentration of useful potassium in the plasma. At the same time, the drug "Captopril", the instruction explains this in detail, does not affect the heart rate, but lowers the pressure.
Tablets are well absorbed in the body. In order to speed up the onset of action, prescribe "Captopril" under the tongue, preferably before meals( per hour).Most of captopril( 95%) is excreted in the urine within 24 hours.
"Captopril", the instruction insists on this, take only on the advice of a doctor who chooses the dosage of the drug individually. So when hypertension arterial is most often prescribed on a quarter of the pill twice a day. In the subsequent if necessary, the dose can be increased to 450 mcg per day.
It is especially important to follow the reaction of the body at the first application. If there is weakness or a sharp drop in pressure, the patient should be laid, but treatment can not be canceled.
Who is contraindicated in Captopril? The instruction gives clear instructions. The drug is prohibited for people suffering from
- dysfunction of the kidneys;
- stenosis of the renal arteries;
- by a violation of the outflow of blood from large vessels;
- with Quincke's edema;
- pregnant, lactating;
- excessive sensitivity to ATP preparations;
- autoimmune diseases.
Since "Captopril" is a fairly strong remedy, it can cause side effects in which the drug will have to be canceled. Among the adverse reactions:
- itching, swelling, burning;
- impaired liver and kidney function;
- distortion of taste and olfactory perceptions;
- abdominal pain, accompanied by a disorder of the stomach, sometimes with nausea, vomiting, diarrhea;
- the occurrence of angina pectoris;
- myocardial infarction;
- dizziness, pain in the temples;
- sleep disturbance;
The question arises: is the use of the drug justified, if it has so many possible side effects. Justified, but only on the advice of a doctor.
Firstly, the correctly selected dose and the careful attitude to the anamnesis of complications do not cause.
Secondly, treatment should be controlled by specialists who can cancel drugs or quickly remove negative effects.
In case of overdose or unexpected reactions, Captopril, the instruction explains this, is eliminated from the body by dialysis, and with a sudden drop in pressure, the composition of the liquid in the body is restored by intravenous sodium chloride.
"Captopril" is available in tablets. Auxiliary substances in it are milk sugar, microcrystalline cellulose, stearic acid and corn starch. The active substance is called the same as the drug itself - captopril.
"Captopril", as well as its version of "Captopril Akos" are available in the form of capsules or tablets.
The drug under this name is produced in Russia, Belarus, Jordan, India and Slovenia.
However, they have analogs that contain the same medicinal substance, but are manufactured in other countries. This "Epsitron", produced in Cyprus, the Yugoslav "Katopil".
All these drugs have a similar effect, but can differ in the degree of purification of the active substance, a set of excipients. They are different in price.
This is why it is best to visit a doctor and listen to his advice before changing the drug.