"Tizin Xylo BIO": instructions for use, description, composition and reviews

Life with a runny nose loses its charm, because people are concerned about headaches, nasal congestion, difficulty breathing, irritation of the mucous membrane and a stream of discharge from the nose. At this point, you want to get rid of the disease as soon as possible, and Tizin Xylo BIO will be an excellent assistant in this situation. He quickly removes stuffiness, removes irritation, restores normal breathing. Has a natural composition. Even children can use it( from two years old).

Composition and form of the preparation

"Tizin Xylo BIO" is a nasal spray. It has the non-proprietary international name "Xylometazoline".

Produced in a dosage of 0.05% and 0.1% by 10 ml. The drug is packaged in polyethylene bottles of white color, which have a dispensing device and a lid. In the box, in addition to the vial is an instruction for use. The volume of the vial( 10 ml) is calculated for 140 doses.

The drug contains the active component of xylometazoline hydrochloride: 0.5 mg for a dosage of 0.05% and 1 mg for 0.1%.The volume of the active substance in one pea for 0.05% is 0.035 mg of xylometazoline hydrochloride;for 0.1% - 0.14 mg. Auxiliary elements are glycerol, purified water, sorbitol, sodium hyaluronate, sodium dihydrogen phosphate dihydrate, sodium phosphate dihydrate and sodium chloride.

The solution is a colorless and transparent liquid with a slight yellowish tinge.

Pharmacological characteristics

Tisin Xylo BIO Spray is an anticongestive medication( vasoconstrictor).

Active substance - xylometazoline - refers to the derivatives of imidazole. This alpha-adrenergic stimulant removes the swelling of the nasal mucosa in a few minutes and restores breathing in rhinitis.

Hyaluronic acid delicately helps to restore the normal operation of the nasal cavity, removes dryness. Supports mucous in moistened condition.

The effect of the drug begins 5-10 minutes after administration.

The drug is intended for topical use only and is almost not absorbed by the walls of the nasal cavity. The concentration of the active component in the blood reaches that minimum value when it is not possible to determine it by analytical methods. Pharmacokinetic studies in humans have not been conducted.

The effect of "Tizin Xylo BIO" during pregnancy and during breastfeeding has not been studied. It is also not known whether the active substance enters the breast milk. Therefore, during these periods of life from the use of nasal spray is better to abandon.

Indications for use

The drug helps to remove swelling of the nasal mucosa in rhinitis. It can be a hay fever, allergic rhinitis or ARI with symptoms of rhinitis.

The drug promotes the rapid removal of mucus in paranasal sinusitis. A similar action of the spray is also observed in the inflammatory processes of the middle ear caused by the common cold.

"Tizin Xylo BIO" for children of the age group 2-6 years has a dosage of 0.05%.Adults and children from 6 years of age are prescribed a drug with an active substance concentration of 0.1%.

Contraindications

In the treatment with Tizin Xylo BIO, a small number of patients( ≥ 1%) can have unpleasant consequences. Therefore, it is worth to abandon the use of nasal spray, if there is a hypersensitivity to any of the substances contained in its composition. Prohibition to use is atrophic rhinitis, thyrotoxicosis. Do not use the drug to treat newborns and toddlers up to two years. Do not use the drug in patients with severe forms of cardiovascular disease, such as ischemic heart disease, severe atherosclerosis, tachycardia, hypertension, angina. Refrain from the therapy of the spray should people who have undergone surgery on the brain.

Caution for the drug, carefully taking into account the benefits and risks, should be a person who uses monoamine oxidase( MAO) inhibitors or similar agents that increase intraocular pressure. Particular attention should be paid to the effect of the drug with narrow-angle glaucoma. Care should be taken by patients with pheochromocytoma, people with impaired metabolic functions( diabetes mellitus) and patients with prostatic hyperplasia.

"Tizin Xylo BIO": instructions for use

Nasal spray is prescribed by a doctor only for topical use. Thus, adults and children's group from six years old are shown a drug with a dosage of 0.1%.In this case, the drug is used up to three times a day. Each time, only one portion of the drug is administered into the nasal passageway. The daily dose may fluctuate depending on the individual characteristics of the organism, the sensitivity to the drug and the achievement of a clinical effect.

Babies at the age from 2 to 6 years are shown "Tizin Xylo BIO"( the instruction for use advises to consult a doctor before using the medication, as improper treatment can provoke the most negative consequences for the organism) with a concentration of active substance of 0.05%.The drug is administered one dose per nostril once or twice a day.

Nasal Spray should not be used for more than five days. Repeatedly this drug can be used only after a few days.

In chronic rhinitis, the drug is used only under medical supervision, since there is a risk of atrophy of the nasal mucosa.

Side effects of

Not so harmless is the nasal spray "Tizin Xylo BIO".For children( instructions for use are attached and should be studied before treatment), the use of this tool can result in negative reactions, however, adults can also suffer. The drug can cause a slight irritation of the nose, which manifests itself in the form of sneezing or burning.

According to experts, reactive hyperemia or swelling of the nose is often enough after the remedy. Prolonged use of xylometazoline or excess of recommended doses sometimes lead to a burning sensation in the nose and excessive dryness of the mucosa. Even in this situation, a nasal congestion with progressive medicamentous rhinitis may occur. Some patients experience paresthesia, hypersecretion and sneezing. Such phenomena can continue for a week after completion of treatment. Prolonged use in some cases provokes the development of chronic inflammatory processes of the nasal mucosa, which cause the formation of dry crusts and are diagnosed as dry rhinitis.

From the side of the nervous system, headache, sleep disturbance, insomnia, depressive conditions, excessive fatigue, a malfunction in the visual apparatus were revealed.

In a few cases, the cardiovascular system suffered. Intranasal use of sympathomimetics has caused a number of phenomena such as arrhythmia, increased heart rate, tachycardia and an increase in the blood pressure index.

Overdose

Spray Tizin Xylo BIO( instruction strongly recommends adherence to the indicated doses) in cases of overdose or accidental administration of the drug may cause the following symptoms:

• dilated pupils;
• nausea and vomiting;
• fever;
• muscle cramps;
• cyanosis of the skin;
• tachycardia and arrhythmia;
• collapse;
• cardiac arrest;
• hypertension;
• psychoneurological failures;
• violation of normal breathing;
• pulmonary edema.

Overdose can provoke a suppression of the functioning of the entire central nervous system of the body, in which there is drowsiness, lower body temperature, bradycardia, significant lowering of blood pressure, respiratory arrest, coma.

If the body has been injected with a volume of the drug exceeding the norm, you should drink activated charcoal and wash the stomach. In some cases, artificial respiration with oxygen is indicated.

To reduce pressure, doctors recommend using 5 ml of "Fentolamine", diluted with saline for intravenous administration. You can also take 100 mg of this drug inside. Do not use vasopressor drugs. If necessary, you can resort to antipyretic or anticonvulsant drugs.

Special instructions

As already mentioned, the use of the drug "Tizin Xylo BIO" for children( reviews say that it helps to quickly restore breathing, but also causes a burning sensation in the nose) can turn into trouble. Therefore, do not use the remedy for more than seven days, as this can provoke reactive hyperemia of the nasal mucosa. As a result, the feeling of stuffiness is constantly observed, which causes you to use the spray again and again. There is an addiction to the drug. This process provokes chronic swelling of the nose, ozona.

In order to avoid dependence on the drug, it is advisable to inject the solution alternately into one and the other nostril with prolonged use. This will reduce the impact of sympathomimetics and ensure partial breathing.

Interaction with

medicines When a combination of nasal spray "Tysin Xylo BIO" with MAO inhibitors from the discharge of tranylcypromine or with antidepressants of the tricyclic series, an increase in blood pressure may be observed. And also disruption of the cardiovascular system.

"Tizin Xylo BIO": reviews

Nasal spray has caused a lot of different disputes. People say that the drug is good, but only for short-term use, as it is addictive, so it should be used strictly according to instructions and not more than a week. Patients note that it quickly removes puffiness and restores breathing "Tizin Xylo BIO". Reviews pay attention to the fact that it removes allergic stuffiness, runny nose, spray is convenient to use. It is worth the drug is inexpensive, while fully coping with its task. Does not dry the mucous membrane of the nose due to the presence of hyaluronic acid in the composition. Economical. Has a long tip, easy to use.