Glucose 5%: instructions, indications
In what dosage is 5-percent glucose assigned? The instruction of this tool is described below. Also below are its properties, indications and methods of application.
Glucose 5%, the instruction of which is described below, contains dextrose monohydrate. This is an infusion drug, produced in glass containers, plastic containers, as well as in polymer bags packed in a pack of paper.
Properties of medicament
How does glucose work 5 percent? The instruction states that this agent takes part in the metabolism in the body, and also enhances the reducing and oxidizing processes, improves the antitoxic activity of the liver and increases the contractile activity of the heart.
One can not help saying that the infusion of such a solution is partially filled by the H2O deficit. Entering the tissues of the body, dextrose is phosphorylated and converted into glucose-six-phosphate, which is included in the main links in the metabolism of the human body.
Features of the drug
What is remarkable about glucose 5 percent? The instruction says that such a solution has a metabolic and detoxifying action, and is also an important source of digestible and valuable nutrients.
In the process of dextrose metabolism in tissues, a huge amount of energy is produced, which is extremely necessary for the normal functioning of the body.
The solution in question is isotonic. Its energy value is 200 kcal / l, and the approximate osmolarity is 278 mOsm / l.
How does the absorption of a solution such as 5% glucose occur? Instruction( the newborn is prescribed only according to indications) states that dextrose metabolism is carried out through lactate and pyruvate to the water of carbon dioxide with subsequent release of energy.
This solution is absorbed completely, the kidneys are not excreted( observation in the urine is a pathology).
Additional pharmacokinetic properties of this drug are determined by the agents added to it.
Indications for the administration of
Solution Why should patients be assigned a 5% glucose dose? Instruction( for children and adults this drug is recommended for the same indications) reports that this remedy is used in the following cases:
- with extracellular isotonic dehydration;
- as a source of carbohydrates;
- for the purpose of breeding and transporting parenterally administered drugs( i.e., as a base solution).
Prohibitions for the introduction of
When are patients not assigned a 5% glucose? Instruction( for cats this tool should be recommended only by an experienced veterinarian) speaks of such contraindications as:
- coma hyperosmolar;
- diabetes mellitus decompensated;
- reduced glucose tolerance( including metabolic stress);
With care, glucose is prescribed for heart failure of decompensated chronic type, hyponatremia, chronic renal failure( in oliguria and anuria).
5-Percent Glucose: Instruction
For dogs and other pets, this medication is administered on a case-by-case basis, strictly according to the indications. The same applies to people.
Isotonic solution of dextrose should be injected into the vein at a maximum rate of up to 150 drops per minute. The recommended dosage for adult patients is 500-3000 ml per day.
For newborn infants and infants with a body weight of up to 10 kg, this medication is prescribed at 100 ml / kg per day. Exceed these dosages is not recommended.
People with diabetes mellitus should be administered dextrose only under the control of its content in urine and blood.
The recommended dosage for the use of the drug for the purpose of breeding and transporting parenterally administered drugs is 50-250 ml per 1 dose of the agent administered.
Side effects of
If the substance is used correctly, undesirable reactions are unlikely. In some cases, the glucose solution causes the development of hyperglycemia, fever, hypervolemia, acute left ventricular failure and polyuria.
Local reactions in the form of thrombophlebitis, infection, bruising and local soreness may also occur.
In veterinary practice, the use of an isotonic glucose solution is very much in demand. Such a drug is actively used to replenish the body of animals with liquid and nutrients.
As a rule, this remedy is given to cats, dogs, sheep and other animals with significant fluid loss, intoxications, shock phenomena, poisonings, liver diseases, hypotension, gastrointestinal diseases, atony, acetonemia, gangrene, cardiac decompensation, hemoglobinuria and others.states.
The diluted and weak animals are considered to be the energy solution.
Dosage of the preparation and the method of its administration
To pets 5% glucose solution is administered intravenously or subcutaneously. At the same time adhere to the following dosages:
- to cats - 7-50 ml;
- to horses - 0,7-2,45 l;
- to dogs - 0,04-0,55 l;
- for small cattle - 0,08-0,65 l;
- to pigs - 0,3-0,65 l;
- to cattle - 0.5-3 liters.
With subcutaneous administration, the indicated dose is divided into several injections, which are done at different locations.