"Cefodox" preparation: instructions for use, reviews and analogues
It is not a secret for anyone that antibiotics not only help to cure infectious and other diseases, but also are extremely harmful to the liver and intestinal flora. However, without their use, it is rather difficult to do in the process of fighting microorganisms that have high sensitivity to them.
Today we will tell you about what diseases are prescribed such an antibiotic drug as "Cefodox".Instructions for taking this medicine, its release forms, cost and properties will also be presented in this article.
Composition, form, packaging of the antibiotic
The antibiotic "Cefodox" goes on sale in two different forms. Consider their composition and packaging in more detail:
- Tablets of 100 and 200 mg, film-coated. They contain such an active substance as cefpodoxime. In addition, the preparation also contains auxiliary constituents in the form of iron oxide, OY-L white oader, sodium croscarmellose, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, silicon dioxide and sodium lauryl sulfate. The medicine is sold in aluminum blisters, packed in cardboard boxes.
- Powder "Cefodox".A suspension made of a porous mass contains an active ingredient such as cefpodoxime. In addition, the composition of the medicament includes additional elements in the form of an emulsion of simethicone, citric acid, sodium saccharin, xanthanum dextrin, carboxymethylcellulose, corn starch, hydroxypropyl cellulose, vanillin flavor, microcrystalline cellulose, silica and sucrose. Medicinal powder comes on sale in bottles of 50 and 100 ml.
Action of the drug
What is a "Cefodox" medication? The instruction says that it is a semisynthetic antibiotic belonging to the third generation of cephalosporin drugs.
The bactericidal effect of this agent on the human body is due to the acetylation of the membrane transpeptidase of the bacterial cell wall.
High sensitivity to this drug is observed in many gram-negative microorganisms. It also adversely affects some Gram-positive bacteria.
A slight sensitivity to the drug is noted in low-sensitivity anaerobes.
One can not help saying that the active substance of this drug does not affect most strains of enterococci, clostridia, mycoplasmas, legionella and chlamydia, as well as strains of methicillin-resistant staphylococci.
Kinetic properties of the drug
Suspension and tablets "Cefodox"( 100, 200 mg) are actively absorbed in the human digestive tract.
The bioavailability of this medication is 52%.After ingestion, the medicine falls into virtually all secrets and tissues of the body, and then accumulates in them( in muscles, kidneys, lungs, bone tissue, liver).
It should also be noted that this drug penetrates into the cerebrospinal fluid. This happens through capsules of abscesses.
The active substance of the drug is cefpodoxime, it is not metabolized. It is excreted together with urine.
Indications for use
What are the aims of the antibiotic "Cefodox" for children and adults? According to experts, this drug is actively used for various infectious diseases, which were caused by microorganisms that have high sensitivity to it.
So, the agent under consideration is prescribed for:
- bronchitis, pneumonia;
- tonsillitis, otitis, sinusitis, pharyngitis, laryngitis;
- infectious lesions of joints, soft tissues, skin and bone tissue;
- pyelonephritis, cystitis( moderate or mild severity);
- proctitis, urethritis and cervicitis having gonococcal origin.
Contraindications to the use of
The drug "Cefodox", whose price is about 450-550 rubles, is not assigned to patients with hypersensitivity to its constituent ingredients.
It should also be noted that medication in the form of tablets should not be given to children under 12 years of age. As for the suspension, it is not recommended for babies up to 5 months of age, as well as for people with lactase deficiency, galactose intolerance or malabsorption syndrome for galactose and glucose.
Antibiotic "Cefodox": instruction for use
The drug in the form of tablets is prescribed only to adults and adolescents from the age of 12 years.
For infectious diseases of the upper respiratory tract and urogenital system, the daily dose of this medication is 200 mg, and for pneumonia or bronchitis 400 mg.
Depending on the dosage of the drug, it is taken once or twice a day. The duration of therapy is determined by a specialist and depends on the characteristics of the disease.
The elderly are not required to adjust the daily dose.
How should I prepare a suspension of "Cefodox"?The instruction says that this requires first shaking the bottle, and then adding cold water( boiled) to it. In this case, it must be ensured that the liquid reaches the mark indicated on the container.
Add water to the powder preferably in two steps, vigorously shaking the bottle and achieving a homogeneous mass.
Take the drug suspension preferably with food. The interval between its methods should be about 2 hours.
If the drug was administered to a child from the age of five months, then its daily dosage should be 10 mg per kg of body weight. The maximum amount of the drug per day is 400 mg.
Side effects after taking
Receiving tablets or suspensions of "Cefodox" can cause the following side effects:
- diarrhea, headache;
- vomiting, itching of the skin;
- nausea, rash;
- increased hepatic transaminases;
- violation of thrombocytopoiesis and leukocytopoiesis;
- increase in urea and creatinine in the blood;
- eosinophilia.
Reviews about the drug and its analogues
You can replace the antibiotic drug "Cefodox" with such means as "Tsefpotek", "Doccef", "Zinacef", "Acef", "Zocef" and others. However, these medicines should not be used alone.
Adult patients, as well as parents of young children, leave mostly positive responses about this medication. According to their reports, the antibiotic "Cefodox" works rather quickly, especially with infectious diseases of the urinary system and upper respiratory tract. In addition, it effectively manifests itself in bronchitis and other inflammatory processes.
It should also be noted that the agent under consideration contributes to the immediate disappearance of such unpleasant symptoms as pain in the body and high fever.
As for side effects, after taking "Cefodox" they are extremely rare.