"Ibrans"( palbocyclibe): price, analogues. Where is cheaper to buy Ibrans?
Breast cancer is the second most common among cancer diagnoses given to women. Malignant tumor occurs in the tissues of the mammary gland and, when the disease develops, metastasizes to other organs. In the fight against this disease in many countries around the world, the effective agent "Ibrans", produced by the American company Pfizer, is used.
The main active substance of the drug is palbocyclob, announced in 2013 as a fundamentally new drug for fighting metastatic cancer. He is appointed in the treatment of patients in postmenopausal women who have not previously received systemic therapy. The effect of such treatment allows prolonging the life of patients without progression of the disease, which in turn significantly postpones the timing of the use of chemotherapy and hormonal drugs.
Where can Ibrans buy cheaper
Unfortunately, the cost of the described tool can not but afflict those who need it. So, in Moscow, the price of the Ibrans capsules was set at 257,000 rubles. But in cases where the cost of a vital preparation seems to be too heavy, the site
Note that the generic is much cheaper at times, not because it is less effective. It has absolutely the same active substance, but its cost does not include the company's development and advertising costs, which significantly reduces the cost of production and, as a consequence, reduces the retail price of the drug.
Proceeding from what has been said, it can be stated with certainty that the price fixed for the generic drug "Ibrans" is not at all a sign of its insufficient effectiveness.
Application of the preparation
The palbocyclib, which is part of the Ibrans preparation, is characterized by the ability to block the activity of enzymes called cyclin-dependent kinases( CDKs), which promote cell growth and division. With the development of cancer, their activity leads to the fact that carcinogenic cells begin to divide uncontrollably.
Use the described agent to combat locally advanced or metastatic breast cancer in women. Typically, it is prescribed in conjunction with letrozol patients in postmenopausal or fulvestrant - patients with symptoms of progression of the pathology, manifested after hormonal therapy.
The cycle of treatment with the drug "Ibrans" is 28 days( 125 mg once a day) - the capsules take 3 weeks, after which they take a break during the week. Take capsules should be combined with food, and do it better at the same time.
Side effects of
During treatment with Ibrans capsules, there are certain side effects. Most often they are:
- development of neutropenia( low level of white blood cells fighting infection);
- manifestations of stomatitis;
- enhanced hair loss - alopecia;
- nausea, indigestion;
- feeling tired;
- increased risk of infection.
In connection with the above, the appointment and control of the use of the drug "Ibrans" should be performed only by a specialist who has experience working with antitumour agents.