"Microzyme"( remedy): reviews. Enzyme preparation
Is the drug "Microzyme" effective - a medicine whose patient reviews you can find in the materials of this article? Today we will talk about this. Also, from the material, you will learn about the diseases in which such medication is prescribed, how much it costs, whether it has side effects, analogs and contraindications.
What substances does Microzyme( medicine) contain? Experts' feedback indicates that the active element of this drug is pancreatin. As auxiliary substances, this agent contains eudragit, triethyl citrate, simethicone, talc, gelatin, water, sodium lauryl sulfate, methyl parahydroxybenzoate, dyes and propylparaben.
In what form can I buy enzyme preparations of this type?"Mikrazim" goes on sale in the form of capsules. They have a transparent case and a brown cover. They contain cylindrical or spherical pellets of light brown or brown color. In this case, the granules of the preparation have a characteristic odor.
Capsules 10 000 U and 25 000 U can be recommended for treatment.
Pharmacological action of the enzyme preparation
What are the properties of this medication? It is a remedy that belongs to the last generation of enzyme preparations. It contains an active ingredient such as pancreatin. It is an enzyme that takes an active part in digestion processes.
As it is known, pancreatin includes substances such as lipase, amylase and protease. They are enzymes of the pancreas and contribute to the process of assimilation of fats, carbohydrates and proteins.
Gelatin capsules contain granules of pancreatin that resemble mini-microspheres that are resistant to gastric juice. This effect is provided by a special coating.
Thus, enzymatic preparations of this type take a direct part in digestion, passing through the intestine. They do not exert any influence on the stomach. After what time does "Microzyme"( medicine) come into play? Experts say that the enzymes begin to release in the small intestine. After that they promote digestion of food, as well as normalization of digestive processes.
After taking the capsule inside, it dissolves within a few minutes in the stomach, and then enters the intestine, where the mini-microspheres are released. The effect of the drug comes in about 40 minutes. However, only its local impact is noted. The medicine is not absorbed in the intestine. The release of the substance is carried out together with feces.
Indications for use
The drug "Microzyme" is recommended to take in the following cases:
- For symptomatic therapy of digestive disorders( for example, gastritis with low acidity, occurring in chronic form, functional dyspepsia, liver and biliary tract diseases, small or large intestine, in the presence of which their evacuation function is violated, and also after partial removal of the intestine, gallbladder or stomach).
- As a substitute treatment for people with pancreatic insufficiency( eg, in cystic fibrosis, chronic inflammation of the pancreas, pancreatic tumors, and after its removal).
- In case of complex preparation for X-ray examination or ultrasound of the abdominal cavity.
- To ensure the processes of digestion of food during normal operation of the digestive system( for example, overeating, eating very fatty and high-calorie foods, breaking chewing, prolonged immobilization, etc.).
Contraindications to the use of
Under what conditions can not take "Microzyme"( medicine)?The doctors' comments indicate the following prohibitions:
- intolerance to the patient of pancreatin or its components;
- exacerbation of chronic changes in the pancreas;
- inflammatory phenomena in the pancreas, especially occurring in the acute form.
Medicinal preparation "Microzyme": instruction
According to the instructions accompanying the drug, 10,000 units of pancreatin should be taken after eating or during a meal. In this case, drink a medicine with a lot of liquid. Capsule is not recommended to chew or divide. If the patient can not take it completely, then its contents must be mixed with water or food. The resulting mixture must be swallowed without chewing.
Small patients under 4 years with a diagnosis of cystic fibrosis are indicated to receive 1000 units of lipase per kilogram of body weight. After the onset of four years of age, children should receive about 500 units of lipase per kilogram of body weight. The maximum allowable dosage is 10 000 U / kg per day.
For steatorrhea and diarrhea, it is recommended to take 25 000 units of the drug every time you eat. The maximum allowable dose is 35,000 units.
Signs of an overdose of
What are the symptoms that occur when taking high doses of "Microzyme"?An analogue of this drug and the medication itself can cause rather strong constipation, as well as hyperuricemia and hyperuricosuria. With such signs it is necessary to cancel the treatment, and also take a lot of fluids and conduct symptomatic therapy.
Side effects of
In most cases, the preparation "Microzyme" is tolerated by patients quite well. However, in rare cases, it can cause some side effects. In this case, the medicine should be canceled or its dosage adjusted.
Most often, the following side effects occur in patients:
- skin allergy( rash, urticaria);
- nausea and vomiting;
- discomfort in epigastrium;
- increased uric acid in blood and urine tests.
There have also been reported cases of narrowing of the intestinal lumen in patients diagnosed with cystic fibrosis.
When combining the drug "Microzyme" with other medicines, it should be borne in mind that against its background, iron and folic acid absorption may decrease. Bioavailability of the drug is reduced if it is simultaneously taken with antacids, which contain magnesium hydroxide or calcium carbonate.
For prolonged admission, the patient's health should be clearly monitored.
There is a decrease in the pharmacological effectiveness of the drug in helminthic invasions, dysbiosis, duodenosis and acidification of intestinal contents. Also, the effectiveness of the medication is reduced if it is taken after the expiration date.
If the drug is stored at high temperature, then the activity of its mini-microspheres decreases rather quickly.
The ability of a person to concentrate, drive a car or work with complex mechanisms does not affect the intake of the drug.
During the therapy of the capsule, always drink plenty of fluids. However, alkaline water is not recommended.
Medication "Microzyme": price, analogues
The analogues of the drug for the active substance are the following drugs: Lycresse, Pancrenorm, Gastenorm, Pancreal, Creon, Panzinorm, Enzistal, Pancreatin, "Pankrelipaza", "Panzim" and others. But you can only replace the prescribed medicine with generic medicine after consultation with your doctor.
The cost of the drug is not very high. On average, the price for 20 capsules is 150-400 rubles and depends on the dosage.
Pregnancy, children, breastfeeding
For the treatment of children, the drug is prescribed only by pediatricians. During pregnancy and during breastfeeding, the medication can be taken only if the benefit from it exceeds the probable risk.
It should also be noted that to date there is no data on the penetration of pancreatin into breast milk.
Reviews of patients about the enzyme drug
Most reviews about the preparation "Microzyme" are positive. Patients observe a marked improvement in their condition with regular intake of this medication while eating. At the same time, they note that it not only helps with diseases of the digestive and pancreatic organs, but also helps to overcome all the unpleasant symptoms that arise during overeating.
However, the doctors' reviews indicate that this medicine must be taken only on indications. Otherwise, his uncontrolled reception may not give the expected effect.