What helps "Sulgin"?Indications for use, instructions, reviews
What is Sulgin medicine? What helps, how to take this remedy? Answers to all the questions you will find in this article.
Form, composition of
Before you tell us about what helps "Sulgin", you should tell in what form this drug goes on sale. This medicine can be purchased in the form of tablets, the active ingredient of which is sulfaguanidine, and additional substances - primogel, calcium stearate and starch.
Features of the drug
The drug "Sulgin" from what helps? According to the attached instructions, this drug has antidiarrheal and antibacterial action. It is highly active against gram-negative and gram-positive bacteria, including intestinal pathogens.
This medication is poorly absorbed when administered orally. It operates mainly in the lumen of the intestine.
The active substance of this drug - sulfaguanidine - inhibits dihydropteroate synthetase and competes for receptors with p-aminobenzoic acid. This effect of this component leads to a delay in the biological synthesis of tetrahydrofolic acid, which is necessary for the synthesis of purines and pyrimidines in the cells of the pathogen.
What helps "Sulgin"
Specialists point to the following indications of the drug under consideration:
- bacterial dysentery;
- colitis or enterocolitis with signs of diarrhea;
- preoperative preparation for surgical interventions on the intestine.
Medication "Sulgin" from what helps? Tablets for oral administration are often used in the presence of carriers of typhoid fever or dysentery or suspected of it.
How to use
Now you know what the "Sulgin" helps. How should this medication be used correctly? In acute intestinal infections, this remedy must be taken orally. On the first day of therapy, appoint 1-2 g to 6 times a day. As for the second and third days, this dosage is maintained, however, the frequency of administration is reduced to 5 times a day. On the fourth and fifth day the frequency of application of this drug in a dose of 1-2 g is up to 4 and up to 3 times a day, respectively.
The duration of treatment with this medication should not exceed more than two weeks. Children under 3 years are recommended to take 200 mg of the drug per kg of body weight per day( divide by three times) within one week.
Babies of 3 years of age give 400-750 mg of funds up to 4 times a day.
In the process of carrying out preventive measures for postoperative complications, patients are recommended to take 50 mg of medication per kg of weight three times a day for 5 days before the intervention, and then for another week after the operation.
Side effects of
After finding out what helps "Sulgin", you should definitely familiarize yourself with its side effects. According to the instruction, after application of this remedy, the following negative effects are often observed in patients:
- depression, myalgia, headache, necrolysis, apathy, photosensitivity, tremor;
- rash, dizziness, itching, neutropenia, nausea, thrombocytopenia, gastritis, agranulocytosis, cholestasis, anemia;
- fever, bronchospasm, vomiting, arthralgia, diarrhea, crystalluria, anorexia, polyuria;
- glossitis, increased urea concentration, stomatitis, toxic nephropathy, erythema polymorphous-bullous;
- increased transaminase concentration, renal damage, hepatitis, hematuria, interstitial nephritis, myocarditis toxic allergic;
- oliguria, hypercreatininaemia, epidermal edema angioedema, anuria.
Overdose cases of
When taking higher doses of Sulgin, symptoms may occur that are characteristic of all sulfonamide drugs( eg, vomiting, fainting, nausea, dizziness, intestinal colic, fever, headache, depression, hematuria, crystalluria).
Treatment of such conditions is carried out by canceling the medication, as well as rinsing the stomach, drinking plenty and forced diuresis.
In case of acute necessity, the medicament in question can be used together with other antibacterial agents and sulfonamides, which are absorbed well from the intestine.
In the process of treatment, "Sulgin" is recommended to intensify diuresis, and also to take vitamins of group B.
Consumer reviews of
The majority of patients taking the preparation "Sulgin" are satisfied with its curative effect. They argue that this remedy is good and quickly enough to eliminate all symptoms of intestinal poisoning, including diarrhea.
Despite all the positive feedback, it should be noted that sulfaguanidine, as well as medicines based on it, have long been banned in developed countries because of their extreme nephrotoxicity.