The preparation "Aleron": the instruction on application, the description, analogues
Why do you need Aleron tablets? Instructions for use, the indications for taking this medication will be described later. Also from the article you will learn about whether it is possible to give the drug to children, whether it has contraindications, whether it causes side effects, etc.
Description, composition and packaging of
What components does the "Aleron" medication contain? The instruction, the description of the preparation, is reported that its active substance is levocetirizine dihydrochloride. Also, the composition of the medicinal product includes auxiliary components in the form of lactose monohydrate, corn starch, magnesium stearate, sodium starch glycolate( type A), colloidal silicon dioxide and microcrystalline cellulose.
In which packaging can you buy the drug "Aleron"?The instruction of this medicine is enclosed in a cardboard box. It also contains blisters with white and round tablets in a film shell.
Pharmacological features of
What features does the "Aleron" medication have? Instruction for use reports that it is an antiallergic agent. He is referred to the group of antihistamines of the third generation.
The active component of the drug is able to provide anti-inflammatory, antipruritic, antiexudative and anti-allergic effects. Also this drug has a pronounced antihistamine effect.
Principle of operation
How does the preparation "Aleron" work? The instruction says that levocetirizine is capable of blocking peripheral H1-histamine receptors, as well as preventing the release of histamine due to the stabilization of mast cell membranes.
According to the experts' reviews, the M-cholinergic and serotonin receptors do not exert any influence on the medicament in question.
To achieve a therapeutic effect, the amount of levocetirizine required is half that of cetirizine. This is due to the fact that the first component forms a more pronounced relationship with the receptors.
After receiving the drug, the production of chemokines decreases. Chemotaxis is also inhibited, the formation of pro-inflammatory cytokines decreases, eosinophil adhesion and expression of molecules are slowed.
The release of IgE-dependent histamine, leukotriene C4 and prostaglandin D2 is reduced by the action of the drug. In addition, the drug has a depressing effect on the thrombocytoactivating factor of the skin.
Properties of the drug
What properties are inherent in the drug "Aleron"?The instruction informs that this medication considerably facilitates the severity of the symptoms of various allergic reactions( for example, allergic rhinitis).
Patients who regularly suffer from seasonal allergies can safely use this remedy to improve their well-being, as well as to prevent the appearance of unpleasant symptoms.
According to the experts' reviews, this medication is effective for bronchial asthma and cold urticaria. In this case, its active component does not have a toxic effect on the heart, nor does it inhibit the central nervous system.
Pharmacokinetic parameters of
Is it possible to take Aleron at the same time as food? The instruction says that food does not have any influence on the absorption of this medicine( to some extent it can reduce the rate of absorption).
The drug is almost immediately absorbed from the digestive tract. Its level of bioavailability is 100%.The maximum concentration of the main substance in the blood is noted after 50-60 minutes. With plasma proteins, the drug binds to 90%.
Only a small part of the drug is metabolized in the liver. As a result, an inactive metabolite is formed. The half-life of "Aleron" is 9-10 hours. Within four days, it is completely eliminated from the body through the kidneys and intestines.
Indications for use
Why is the "Aleron" medication( tablets) needed? The instruction informs that this preparation is prescribed for the purpose of treatment and prevention of allergic manifestations, which can be both acute and chronic.
So, the given preparation can be used at such diseases, as:
- allergic rhinitis;
- hay fever;
- allergic dermatoses, which are accompanied by a feeling of itching, burning, and rashes on mucous membranes and skin;
Contraindications to the use of
What contraindications does the "Aleron" medication have? Instructions for use( for children there are restrictions) informs you that in no case should this product be given to a child under the age of 6 years. Also, the drug is prohibited to be administered under the following conditions:
- renal failure, occurring in severe form;
- high level of sensitivity of the patient to the constituent components of the agent, as well as to the derivatives of piperazine;
- disturbed absorption of glucose and galactose;
- intolerance to galactose.
Preparation "Aleron": instruction for use
Take tablets "Aleron" should only be indicated. They are prescribed to adult patients, as well as children from six years of age.
The drug is taken orally by washing with ordinary liquid. The duration of the course of therapy, as well as the dosage of the medication is determined only by the doctor, depending on the diagnosis.
Typically, the antiallergic agent "Alerone" is prescribed one tablet once a day. The daily dose of this drug should not exceed 10 g.
According to the attached instructions, with a brief contact with the allergen, therapy with this drug should continue for a week. If the patient suffers from hay fever, the course of treatment can last up to one - one and a half months. In acute cases, treatment is extended to six months.
Similarly, the drug "Aleron Neo" should be taken.
The instruction accompanying the medication informs that people with a diagnosis of renal failure should be corrected for the dosage. If the liver is disturbed, the same dosing regimen is used as in normal people.
What are the side effects of Alerone? The instruction( for children and adults) reports that this medication can contribute to the appearance of the following effects:
- a feeling of strong palpitation;
- severe fatigue, headache, aggressiveness, drowsiness, anxiety, weakness, convulsions;
- vision impairment;
- dry mouth and nausea;
- edema and anaphylaxis;
- shortness of breath;
- abdominal pain, myalgia and weight gain;
- urticaria, skin itching and rash.
Signs of an overdose of
When taking high doses of the drug, patients have severe drowsiness or, conversely, a state of overexcitation, followed by drowsiness. When observing such symptoms, the drug should be discarded. The patient should be prescribed gastric lavage, and also give him an enterosorbent.
With simultaneous administration of levocetirizine and drugs whose metabolism is directly related to the cytochrome P 450 system, no interaction is observed. However, with repeated admission of theophylline, the clearance of levocetirizine may be reduced to some extent.
It is not recommended to combine the drug "Aleron" with sedatives.
Levocetirizine does not affect the intake of ethanol in any way.
According to the instructions, the medicine in question is used with special care for elderly people, as well as for those suffering from kidney failure.
During the reception of the antiallergic agent "Aleron" the patient is not recommended to drive vehicles and interact with complex mechanisms.
Pregnancy and lactation
There is no information about the use of the drug "Aleron" in pregnancy. Therefore, in this period, it should be appointed with extreme caution.
Levocetirizine penetrates into the mother's milk. In this regard, for the period of its use, it is necessary to stop breastfeeding.
Analogues and price
There are many drugs that can replace the drug "Aleron".Such medicines include the following: "Aleron Neo", "Glencet", "Alerzin", "Xizal", "Cesera", "Tsetril" and so on.
These drugs have a similar effect. However, they should be used only for the purpose of a specialist.
As for the cost, this medication is not very high. You can buy tablets "Aleron" for 220-240 rubles.
Reviews about the antiallergic drug
The drug "Aleron" is not very popular. Therefore, reviews about him are extremely rare. Of those that are available, we can safely conclude that this medication is fully able to cope with the task. Single intake of tablets allows you to quickly and effectively remove all the symptoms associated with allergies. The preparation considerably facilitates a condition of patients, and also prevents occurrence of undesirable reactions.
Among negative reviews, there are often those who say that the drug in question often causes side effects.