Tablets "Serrata": instructions for use."Serrata": reviews

Is the drug effective, such as Serrata? We will provide feedback on this medication in the materials of this article. Also you will learn about how much it costs the drug, how it should be used, whether it has contraindications and under what diseases it is prescribed to patients.

Composition, packaging, form

What substances are included in the product under consideration? What does this tell us about the instructions for use?"Serrata" contains an active element such as serratiopeptidase. As additional substances, this drug includes sodium starch glycolate, light magnesium carbonate, lactose monohydrate, magnesium stearate and cornstarch.

In the sale, the said medicament comes in the form of tablets, which are coated with an enteric coating. They are placed in the cell packs, which are embedded in cardboard boxes.

Pharmacological properties of

What features are inherent in this drug? What does the instruction for use say about this?"Serrata" is an anti-inflammatory, decongestant and fibrinolytic agent. What is the principle of its operation?

Serratiopeptidase is an enzyme that exhibits a proteolytic action that has been extracted from an intestinal bacterium of a non-pathogenic nature( Serratia E15).This group of microorganisms quite quickly splits bradykinin and fibrin, as well as other mediators of inflammation. Moreover, it exhibits anti-inflammatory and anti-edematous function. This is due to the release of painful amines from inflamed tissues, which is characterized by an analgesic effect.

Instruction for use( "Serrata" is a universal medicinal product) reports that this medication is able to quickly penetrate into places that undergo the inflammatory process and to lyse necrotic tissues and their decay products.

Also considered means reduces hyperemia, catalyzes the absorption and activity of antibiotic agents. In addition, it lowers the viscosity of saliva and promotes the dilution of nasal secretions, facilitating their excretion.

Alpha-2-macroglobulins of blood and serratiopeptidase form an active complex in a ratio of 1: 1.This leads to a masking of the antigenicity of the enzymes without loss of their pharmacological activity. When the enzyme passes to the sites of inflammation, as well as into exudate, the concentration of serratiopeptidase in the blood decreases.

Properties of medicament

Due to the splitting of serotonin, histamine and bradykinin, serratiopeptidase reduces capillary dilatation and reduces their permeability. It also promotes inhibition of plasmin blockers, improving their fibrinolytic activity.

After a decrease in microcirculation and elimination of swelling, sputum is also successfully separated.

Active, as well as additional substances of this drug are enclosed in an enteric membrane. That's why the "Serrata" tablets do not break down in the stomach.

Pharmacokinetics

Where is the Serrata medication absorbed? The instruction informs that the process of absorption of this medication occurs in the intestine. In the blood, its maximum content is found after 60 minutes. A small amount of medication is excreted along with urine.

Indications for use

Thanks to its versatile action, the Serrath medicinal product, the price of which is indicated below, is prescribed for the treatment of various diseases in completely different fields of medicine:

• In surgical practice and traumatology this medication is used for fractures, dislocations, sprains and other injuries. In addition, it is often prescribed for edema, including postoperative. Also, people take pills to prevent possible rejection of the transplant.
• In the otorhinolaryngological practice, the Serrata preparation, whose reviews are positive, is prescribed for otitis, sinusitis and other inflammatory processes( including VDP), which are manifested by difficulty in separating sputum and increased mucus, and also in order to improve the absorption of antibiotic agents.
• In plastic surgery, Serrata tablets are used to increase microcirculation in order to prevent probable rejection of the graft, as well as to reduce swelling after the operation.
• In dermatology, this medication is recommended in the presence of acute dermatoses, which occur with pain syndrome.
• In gynecology, the drug in question is used to eliminate puffiness of the mammary glands due to various diseases. Also this agent is prescribed for an accelerated process of resorption by hematomas, including mastitis.

Contraindications

What are the contraindications for the Serrat tablets? The use of this drug is prohibited:

• with hypersensitivity to serratiopeptidase, as well as other components of the drug;
• in pathological conditions that lead to an increased risk of bleeding or bleeding disorders.

Dosage and instructions for use

"Serrata"( tablets) is given only inwards. In a day, this drug should be taken in an amount of 30 mg, that is, 1 tablet three times.

Food intake does not affect the absorption and effectiveness of the drug. Tablet "Serrata" must be swallowed whole. In no case can it be chewed, as this will damage its enteric membrane. Drink the medication with plain water.

Different types of disease, as well as their severity, require correction of the daily dose of the drug in one direction or another.

Only the treating doctor should select the minimum effective dose and determine the duration of its administration, based on the specific situation.

Side effects of

What side effects can Serat medication cause? The instruction informs, that at reception of this preparation in rare or infrequent cases disturbance of a chair, pains in GASTROINTESTINAL TRACT, a nausea and vomiting is observed.

People who are predisposed to bleeding may develop frequent nasal bleeding and the appearance of blood in the sputum.

In some cases, this drug may trigger allergic reactions that manifest as itching or rashes on the skin, as well as hives.

Overdose with

tablets Taking high doses of Serrat tablets may cause an increase in the above side effects, and in some cases even lead to the formation of internal bleeding. In this case, you must refuse to take the medication and conduct symptomatic therapy.

Drug Interaction

The combination of serratiopeptidase and anticoagulants increases the effect of the latter. If it is necessary to simultaneously take these medications, the patient must be under regular supervision of an experienced specialist who can adjust the dose of an anticoagulant.

Special recommendations

This drug has a direct effect on blood coagulability. Therefore, it should be used with extreme caution, especially when treating with anticoagulants, as well as a person's predisposition to bleeding and pathologies of blood clotting.

Special care should be exercised when prescribing serratiopeptidase to people with painful kidney and liver conditions.

Reviews and the price of the drug

How much does the "Serrata" medication cost? The price of this drug in the amount of 10 tablets is 100-120 rubles.

Reviews about this tool are more positive. Doctors say that this is a universal medicine that can be used in the treatment of inflammatory processes in surgery, traumatology, gynecology, etc.

Patients are satisfied with the results of therapy. They talk about the high effectiveness of this remedy, especially when combined with antibiotics.