"Fibrofid"( gel): instructions for use, description, analogues, reviews
How to use and how much does a medicine "Febrofid"( gel) cost? Instructions for use, the price of the drug will be presented below.
From this article you will learn about what components are included in the composition of the drug, what indications it is assigned to, how it affects a person and whether they have analogues.
Description, composition and packaging of
What is an external remedy such as "Fibrofide"( gel)?Instructions for use, reviews of patients report that it is a 2.5% colorless, slightly opalescent or clear drug( may have a light yellow hue), which includes the lysine salt of ketoprofen.
Also included in the composition of the drug are additional components in the form of polyethylene glycol, propylhydroxybenzoate, triethanolamine, methylhydroxybenzoate, carbomer and purified water.
Pharmacodynamics of the external agent
What are the pharmacological characteristics of the drug "Febrofid"?The gel, the instruction for which is enclosed in a cardboard package, is a local remedy belonging to the NSAID group.
This drug has a pronounced anti-inflammatory, anti-exudative and analgesic effect. The area of application of this medicine is painful areas of the musculoskeletal system( injuries of joints, tendons, muscle tissues and ligaments).
Also considered medication is actively used for lesions of veins, lymphatic vessels, lymph nodes and skin.
After applying the gel, joint pains are significantly reduced, swelling and morning stiffness are eliminated.
Pharmacokinetics of the drug
What are the kinetic characteristics of the drug "Febrofid"( gel)?The instruction for use states that ketoprofen( the active ingredient of the drug) has good penetrating power. After applying the gel to the skin, the active ingredient is quickly delivered to the problematic tissues, resulting in a local analgesic and anti-inflammatory effect.
The bioavailability of this drug is at 5%.The connection with plasma proteins is 99%.In this case, cumulation in the body is not noted.
Ketoprofen is metabolized in the liver.
Approximately 10% of the drug is unchanged and 80% in the form of metabolites excreted by the kidneys.
When should I use the drug "Fibrofid"( ointment)?The instructions for use indicate the following list of pathological conditions:
- uncomplicated injuries or injuries( including sports injuries, ligament and tendon ruptures, sprains, posttraumatic pain syndromes, dislocations);
- painful conditions of the musculoskeletal system, which are inflammatory-degenerative in nature( including arthritis, tendinitis, bursitis, synovitis, lumbago);
- vascular pathologies of inflammatory nature( phlebitis, periphlebitis), lesions of lymphatic vessels and lymph nodes( for example, superficial lymphangitis, lymphadenitis) - in complex therapy.
Also it should be said that this medication is often used for symptomatic treatment of myalgia, neuralgia, pain in the spine, etc.
When can not use the drug "Fibrofid"( gel)?Instruction for use informs us that this drug is prohibited from prescribing for:
- of dermatitis;
- infected abrasions, wounds and burns;
- pregnancy( especially in the third trimester);
- hypersensitivity to the main ingredient and other constituents of the gel, as well as drugs that belong to the NSAID group.
Instruction for the use of the drug "Fibrofid"
The gel "Fibrofid" is designed only for outdoor use.
To achieve the maximum effect from the treatment, a small amount of the drug( a strip of 3-5 cm) should be applied to the skin area that is located above the damaged site. After that, the medication should be rubbed with light massaging movements.
The application of a dry dressing after the procedure is not required. This is due to the fact that the drug in question is well absorbed, does not include dyes, has no smell and does not leave sticky and greasy stains on clothing.
Side effects of
Sometimes, against the background of the use of the drug "Febrofid" in patients there are negative manifestations of an allergic nature. These include reactions such as skin hyperemia, photosensitivity, purpura and skin exanthema.
With frequent and long-term use of the drug "Fibrofid" various manifestations of interaction with other medicines can be formed.
This drug increases the content of "Verapamil" and "Nifedipine" in the blood.
Combination of "Febrofid" with oral anticoagulants, "Cefamandol", antiaggregants, "Cefoperazone", thrombolytic agents and heparin increases the risk of bleeding.
Simultaneous use of gel with glucocorticoids, corticotropin, other NSAIDs and ethanol increases the risk of ulceration and bleeding in the digestive tract.
Joint use of the drug with insulin and oral hypoglycemic agents increases their hypoglycemic effectiveness.
Ketoprofen worsens the effect of antihypertensive and diuretic drugs due to the inhibition of prostaglandin synthesis.
When combined with sodium valproate, platelet aggregation may be impaired.
Special recommendations for the use of an external agent
What should I know before using the drug "Fibrofid"( gel)?Instruction for use informs that this medication can not be applied to areas of skin that are prone to festering or mechanical damage. Also, all precautions should be taken to prevent the gel from getting into the eyes.
If you need to use ointment in a patient with severe kidney or liver pathology, especially for a long time, you need to constantly monitor his health.
If skin rashes occur, discontinue therapy and consult a doctor.
Price and analogues
The cost of the drug "Fibrofid" is about 250 rubles for 30 g. You can replace this medication by such means as Nimulide, Diclofenac, Ketoprofen, Butadion, Bystrumgel, Indomethacin,"Arthrosilen", "Orthofen", "Finalgel", etc.
Feedback from patients
Now you have an idea of how to use the drug "Fibrofid"( gel).Instructions for use, price, reviews about this tool are described in this article.
Most patients respond to the medication in question solely with the positivity of the party. They argue that this drug quickly and effectively removes pain, and also eliminates swelling and inflammation in injured areas.
Also, patients note that after applying the gel, it is quickly absorbed, not stained clothes and leaving sticky spots on it.
As for negative responses, they are extremely rare. As a rule, the latter indicate the occurrence of allergic reactions in patients.