Tablets "Don": reviews, applications, indications, analogues
Many people have heard about degenerative-inflammatory joint diseases today. This is one of the most common problems with which patients go to medical facilities.
Among the drugs that are prescribed by doctors to eliminate the ailment, there are certainly chondroprotectors. One of the most effective tools of this group are tablets "Don".The experts' feedback is confirmed by the fact that this preparation, which contains only one active substance - glucosamine sulfate, has a positive effect on the state of the articular cartilage tissue with deforming arthroses.
But this chondroprotector not only eliminates the symptoms of the disease. After the patient underwent a course of treatment in which "Don" tablets were included, the specialists' comments receive this drug as a means to bring the articular fluid into normalcy and also improve its lubricating characteristics. Such a complex of effects is especially effective in the initial stages of arthrosis.
Dosage form
The Dona tablets from the joints are manufactured by the well-known pharmacological company Rottafarm( Italy).In addition to this form, the preparation is used in the form of powder, packaged in sachets of 5 grams, as well as ampoules for intramuscular injection( 2 ml each).
Dona tablets are in a white carton. The number of them can be different. So, there are packages with a package of 60, as well as 180 white tablets, which have an oblong shape and are coated with a shell.
Composition of
As already mentioned above, the active ingredient in the composition of the "Don" tablets is glucosamine in the form of sulfate. In addition, there are additional substances, namely: microcrystalline cellulose and macrogol 6000, povidone K25 and croscarmellose sodium, magnesium stearate and talc.
Mechanism of action
How does the pathology of the Dona tablet affect the body? Experts say that the mechanism of action of the drug is due to the presence of glucosamine in its composition. This substance, which is a natural structural component of the cartilaginous tissue of the joints. In addition, without glucosamine synthesis of biologically active substances, which ensure the strength of the cartilage itself, is impossible.
What is this element for? Thanks to glucosamine, active growth of connective tissues takes place in the tendons and joints of the joints.
However, with age, the content of this substance, so necessary for our joints, begins to gradually decrease. This leads to the fact that after forty years a person begins to feel disruptions in the functioning of the motor apparatus. Particularly he is concerned about the disruption of the joint surfaces and the reduction of their functions.
What are the "Don" tablets used for? The doctors' comments confirm that the drug prevents premature wear of the cartilage. And in those cases when pathology has already acquired a neglected form, the medicine allows to restore its tissue.
Tablets, which are part of the group of chondroprotectors, make up the deficiency of glucosamine in the body, and also stimulate biochemical processes of hyaluronic acid and synthesis of proteoglycans in the synovial fluid.
The drug "Don" helps increase the permeability of the joint capsule. In this case, the physiological and enzymatic processes that occur in the cells of the synovial membrane and articular cartilage are restored. In addition, the reception of "Don" tablets makes it possible to accelerate the process of sulfur fixation during the synthesis of chondroitin sulfuric acid, destroy enzymes that cause destruction of cartilage, prevent the appearance of superoxide radicals, and also decrease the activity of lysosomal enzymes.
Therapeutic effect of
"Dona" - tablets, the use of which allows to reduce pain in the joints, restore their efficiency and stop the development of deforming osteoarthritis. The drug stimulates the restoration of cartilaginous tissue, providing anti-inflammatory, anabolic, anti-catabolic and chondroprotective effect.
How effective is the medication "Don"?Tablets, the use of which is recommended to those patients to whom the doctor diagnosed "arthrosis", act primarily on the cause of the disease. Their reception allows you to gradually, day after day, restore the broken joint. This action is similar to the construction of a house. For its erection it is necessary to lay a brick to a brick, and as a result a building is obtained.
That's why sometimes negative receive "Don" tablets reviews. The use of the drug should be long. And only after the patient has completed the full course, a positive result will be seen. So, some reduction in symptoms of arthrosis with the reception of "Don" tablets becomes noticeable only after two to three weeks after the beginning of their admission. And the maximum effect the patient feels only after one or two months. After the end of the course of treatment, the result remains for another fifty days.
Scope of application
About the person who is assigned "Dona" tablets, the instruction tells in some detail. To begin complex therapy with this drug is necessary in those cases when the doctor has established the presence of such ailments:
- arthrosis of joints or osteoarthrosis;
- chondromalacia nadkolenikov;
- osteochondrosis of the spine;
- periarthritis;
- systemic diseases in which the osteoarticular system is involved in the pathological process.
How do all these pathologies affect the joints of the Don? And the patients 'testimonials, and the doctors' opinions, say that this drug is very effective. After all, degenerative-dystrophic diseases that occur in joints become a consequence of metabolic disturbances in tissues. In the older age, these pathologies develop due to disparity in physical activity and resistance of the joints themselves. Gradually, in the cells of the cartilage, which is a kind of natural shock absorber, metabolic disturbances begin. This leads to necrosis and destruction of the tissue. After the bone tissue is erased, as during physical exertion the processes of its proliferation begin to become more active.
A negative process reduces the amount of intra-articular fluid that has served as a kind of lubricant to the joints. The person has pain. There is a violation of the function of the joints. The quality of life decreases. Primary osteoarthritis develops.
This same disease can have a secondary nature. Sometimes osteoarthritis develops in young people. This happens due to the suffered injuries or inflammatory joint diseases. Such osteoarthritis proceeds slowly enough. In this case, it does not interfere with the function of the joints( except the hip).
Pathology is treated with agents that improve blood circulation, anesthetics. Physiotherapeutic procedures are also prescribed. However, the main drugs prescribed for the pathologies described above are those that affect the metabolism. Their list includes tablets "Don".
Indications for use, which are indicated in the manual, as well as clinical studies confirm the high efficacy of this drug.
This chondroprotector is also used for changes in the spine that occur in osteochondrosis. Effective pill "Don" and chondromalacia patella, when there is a softening of his cartilage, which is possible after operations on the joints and the transferred injuries. Also, the drug is prescribed for the complex treatment of patients suffering from inflammatory and autoimmune( causing allergy to their own tissues) joint diseases.
For preventive maintenance also recommends the use of tablets "Don" instructions for use. Reviews of patients after the age of forty and athletes confirm a decrease in pain symptoms with significant physical exertion.
Dosage of
How do they take "Don"( tablets)?The instruction to the preparation explains this question in detail. The dosage of the drug directly depends on the degree and severity of the disease. That is why she should be appointed by the attending physician. However, in general, tablets are taken orally 1-2 times three times a day and always with food. The duration of the course can be from one to three months. In each case, the appointment time is appointed by the attending physician. If necessary, the course of therapy can be increased or decreased.
There were no cases of overdose with "Don" tablets. However, this is a pharmacological drug, and you should not abuse its use. The course of treatment should be based on the prescriptions of the doctor and explanations of the instructions.
Contraindications
Like all pharmacological drugs, some restrictions on their use are tablets "Don".Instructions for use and patient reviews suggest that great caution is required in the presence of hypersensitivity to one of the components and symptoms of allergies.
Do not prescribe pills to children who are under 12 years of age. This is due to the lack of sufficient clinical studies on the safety and usefulness of such therapy.
There are no similar data on the teratogenic effect of the drug on the fetus during pregnancy. There is no information about its negative impact on the child during lactation. That is why the use of the drug is prohibited for pregnant and lactating women.
Due to the fact that there are sodium in the "Don" tablets, they are not recommended for people who are forced to follow a sodium diet. During the treatment period, the patient also needs to refrain from significant physical exertion.
Side effects of
The body of each of us is so individual that no one can say with certainty how we will react to the introduction of this or that drug. Various undesirable phenomena can arise also in the case when the pharmacological agent "Don"( tablets) is used. Instructions for use warns that sometimes a patient appears:
- nausea;
- vomiting;
- constipation;
- diarrhea;
- headaches;
- dizziness;
is a general malaise;
- allergic reaction
- visual impairment.
This is how the central nervous system of a person can react to taking a medicine.
Special instructions
Tablets "Don" with special care should be taken by people who are allergic to seafood. After all, the composition contains glucosamine phosphate, which is extracted from the shells of shellfish. Do not take the pill without the care of a doctor and those who have a chronic disease of the type of diabetes.
Comprehensive treatment of
What else tells us about the drug "Don" instruction? Reviews of the tablet for their compatibility are very different. In some cases, the integrated use of drugs significantly increases the effectiveness of treatment. In others, on the contrary, will direct the process of healing in the opposite direction. That is why complex treatment should be conducted under the direct supervision of a specialist.
So, our medicine knows a lot of drugs, the action of which is similar to that which is a pill of the "Don".However, each of these pharmacological agents has its own characteristics. Most often, the treatment prescribed by a doctor includes the use of one of the representatives of a group of chondroprotectors and a drug from another category. This approach is quite understandable. So, tablets "Don" will affect the joint from the inside, and another drug while ensuring the supply of nutrients to the zone, getting rid of pathology. This will ensure the rapid elimination of the problem, the impact on which will be provided simultaneously from all sides.
Dona tablets are well combined with drugs in the NSAID group, as well as with other chondroprotective agents. With their simultaneous administration with drugs designed to relieve inflammation, the effect of coumarin anticoagulants is enhanced. Combine tablets "Don" with sedatives can only after a preliminary consultation with a doctor. Otherwise, the condition may worsen, as well as the appearance of side effects.
Result of treatment
After the spent therapeutic course in patients it is observed:
- normalization of metabolic processes in the affected cartilage;
- cessation of development of processes of destruction of a lining of a cartilage;
- return to normal levels of synovial fluid;
- reduced risk of osteoarthritis;
- reduction of pain syndromes;
- normalization of motor functions in problem joints;
- improving the quality of life;
- reduced costs for treatment;
- elimination of the need for surgical intervention.
Advantages of the drug
The action of the "Don" tablets is positively evaluated by both specialists and patients who took the drug. Doctors often designate this tool, as it is characterized by the following advantages:
- has a high composition efficiency;
- reduces negative symptoms;
- actively nourishes the cartilage;
- accelerates regeneration processes;
- has a minimum list of restrictions;
- rarely causes side effects;
- easy to use;
- can be used together with drugs that are part of the NSAID group, as well as analgesics;
- can be used for patients of adolescence;
- has a large number of positive feedback from specialists and patients;
- for a long time retains its therapeutic effect.
Reviews of patients
Most often, the pillars of the "Don" people respond positively. After the course of taking this chondroprotector, many noted a decrease in the crunch in the joints. Knees and elbows began to bend and unbend much easier. At the same time, the pain decreased.
People rarely give negative reviews about the drug. After all, this remedy is quite effective, and the side effects from its use are infrequent. However, some patients remain unhappy with the result they received after the end of the therapeutic course. They believed that getting rid of soreness and stiffness of the joints would come faster.
It should be remembered that the decrease in symptoms of the disease with the use of "Don" tablets is observed only two weeks after the start of the drug. Perhaps these people before the start of the course did not sufficiently study the instruction to the facility, which indicates its accumulative effect.
Analogues
Joint diseases are very common. That is why pharmacological companies produce quite a lot of funds, the effect of which is similar to that provided by the drug "Dona"( tablets).
Reviews of analogues are usually also positive, and can be considered when included in the course of therapy. Among such preparations are:
1. "Alfluton". Its main component is concentrate, obtained from sprat fish. This remedy is intended for the removal of inflammatory processes, as well as for the elimination of pain. A solution in the form of a solution is used, which is used for injections.
2. "Hondroguard". This drug increases the speed of recovery of joints and increases their performance This drug is also used for intramuscular injection.
3. " Unicum". For those who for some reason do not fit tablets "Don", analogues can always be found in the network of pharmacies. One of the cheapest of them is the drug "Unicum".In its composition is 750 g of glucosamine sulfate. The use of the preparation allows not only to prevent the growth of the process of destruction of the cartilaginous tissue, but also to stimulate its restoration. However, to obtain the effect, the agent will need to take at least six months. With the regular use of this analogue of the "Don" tablets, joint mobility improves. At the same time, the need for taking other drugs included in the NSAID group is reduced. This medication should be administered with caution to those who are hypersensitive to the substances that make up it. Do not prescribe it to pregnant and lactating women.
4. "Sustilak". This is another analogue of the "Don" tablets. In its composition - all the same active substance. Assign the drug for primary and secondary osteoarthrosis, osteochondrosis, chondromalacia of the patella and periarthal periarthritis. Reception is recommended twice a day. The average course is 6 weeks.
It is not necessary to choose independently the same analog of the "Don" tablets. Only the doctor can determine the best drug that is suitable for the treatment of a specific person's joints.