Preparation "Istenon": reviews. Instenon: instructions for use and analogues

What is a tool like "Instenon"?The instructions for use, the price and the properties of this medication will be described below.

Composition, form, description of the medicine

In what form is the above-mentioned drug sold? What does consumers say about this?"Instenon" is available in the following forms:

• Round tablets with a shiny and flat surface, covered with a white coating. The main substances in their composition are: hexabendine( in the form of hexabendine dihydrochloride), as well as ethophylline and etamivan. In addition, the composition of this drug includes additional elements: talc, magnesium stearate, pregelatinized starch, corn starch and lactose monohydrate.
• Transparent and colorless solution "Instenon"( injections), intended for intramuscular or intravenous administration. Its active ingredients are also hexabendine( in the form of hexabendine dihydrochloride), ethophylline and etamivan. As for the auxiliary substances, disodium edetate, water d / and propylene glycol are used as such.

Pharmacology

How does the agent work? What does the doctor say about this?"Instenon" is a combined medicine that improves the metabolism, as well as the blood circulation of the brain.

The effectiveness of this drug is due to the properties of its basic substances. Let us consider them in more detail.

Thanks to activation of the reticular formation, etamivan is able to normalize the work of neural subcortical-stem structures and cortical complexes.

Gekesbordin improves, and also accelerates the process of utilization of glucose and O2 by activating pentose cycles and anaerobic glycolysis. This occurs only in conditions of oxygen starvation and ischemia, when oxidative aerobic phosphorylation is significantly disturbed. Stimulation of anaerobic oxidation is carried out by the energy substrate for the purpose of metabolism and synthesis of mediators, as well as the restoration of synaptic transmissions.

It can not be said that hexobenzidine is able to stabilize the mechanisms of( physiological) autoregulation of blood flow( cardiac and cerebral), which has a direct connection with the action of pyruvate and lactate( i.e., products of anaerobic glycolysis) on the receptor apparatus of capillaries and intracranial arterioles.

What role does etofillin play in the drug "Instenon"?The instruction, the reviews report that this substance activates myocardial metabolism and increases the minute volume of the heart, which further contributes to increasing pressure( perfusion) in ischemic vessels. In this case, systemic blood pressure does not change at all.

The excitatory effect of this phylline on the HC is also manifested by stimulation of the midbrain and other subcortical formations, as well as stem nuclei and centers( including the nuclei of CMN, the center of vegetative regulation, the vasomotor and respiratory centers and the vagus nerve).

When using the drug "Instenon", the analogues of which are listed below, in cases of trauma of the skull and brain( closed), ischemic stroke, neurological disorders are eliminated, the patient's consciousness restored and the vegetative system activated.

Indications

When is the most effective medication? What does this say about the reviews?"Instenon" is indicated for use in:

• post-stroke states;
• diseases of the brain of vascular origin, as well as associated with age-related changes in the patient;
• insufficiency of blood supply to the brain and its consequences;
• dizziness, which was caused by disorders( functional) of the brain.

Prohibitions on the use of

The drug "Instenon"( injections and oral forms of the drug have the same contraindications) is forbidden to appoint with:

• convulsive syndrome;
• state of strong excitement;
• symptoms of increased blood pressure( intracranial), including prolonged headache, vomiting and visual impairment;
• epilepsy;
• hemorrhages in the brain;
• hypersensitivity to ingredient agents.

With care, the medication in question should be used after a stroke, as well as with stenosis of the artery( carotid), arisen due to arteriosclerosis.

Preparation "Instenon": instructions for use

The price of this medication is about 350-400 rubles. How should it be used? Depending on the severity and type of disease, the agent in the form of a solution is administered intramuscularly or slowly intravenously. To do this, apply 1 ampoule of the drug 2 times a day.

The medication can also be administered as a drip intravenous infusion. In this case, it is also prescribed for 1 ampoule 2 times a day together with 250 ml of a 5% solution of levulose.

After improvement of the patient's condition, therapy can be continued with the oral form of the drug. In this case, the tablets are taken orally in an amount of 1-2 pieces three times a day. The maximum daily dosage of this drug is 5 tablets. This therapy is carried out for six weeks.

Side effects

According to experts, the drug "Instenon" rarely causes negative reactions. In some cases, when used in high dosages, the patient may have a headache, as well as decrease blood pressure and develop hyperemia on the skin of the face.

Overdose and interaction

Signs of an overdose of this drug are headaches, facial flushing and tachycardia. To eliminate such conditions, you must cancel the drug, and then resume its use, but at a lower dosage.

With the parallel use of the drug "Instenon" and the means that reduce the activity of platelets( including acid acetylsalicylic), it is possible to increase the antiaggregant effect, which is due to the influence of hexiodine.

When taking caffeine in large doses, it is possible to decrease the therapeutic effectiveness of Instenon.

Special Information

What should patients know about before taking this medication? According to the attached instructions, sometimes with rapid intravenous injection of "Instenon" in the patient significantly lowered blood pressure. In this regard, the duration of infusion of the first dose should not be less than three minutes.

During the period of treatment with this remedy, the patient must be extremely careful when working with dangerous mechanisms and driving a car.

Similar drugs and reviews of

"Instenon" can be replaced by such products as "Cytoflavin", "Armadine", "Glycine", "Boluses of Huato", "Keltikan", "Mexidol", "Cortexin", "Mexiprem", "NucleoCMF Forte "," Neurotropin "," Tryptophan ".It should be noted that these drugs have their own indications and features, so they should be appointed only by an experienced specialist.

What do consumers say about the drug in question? According to their allegations, this medication rarely contributes to the development of any complications, so it is prescribed even for children. His reception significantly improves cerebral circulation, and also eliminates other problems with blood vessels.

The only drawback of this drug is the rapid adaptation of the body to the drug. In this regard, we can safely say that "Instenon" is a course aid that is not intended for continuous use.