"Ciclovir"( tablets): instructions for the use of the drug, description, analogs, reviews

What are the "Ciclovir" tablets for? Instructions for use, testimonials, indications and analogues of this medicine will be presented below. Also, you will learn about how much this drug costs, whether it has contraindications, and what side effects occur against the background of its administration.

Composition, packaging, description and form

In what form is the "Ciclovir" medication manufactured? Instruction for the use of the drug reports that it is sold in the following forms:

• Tablets. Active part of this drug is acyclovir. White flat cylindrical tablets go on sale in contour packs, which, in turn, are sealed in cardboard packs.
• Ointment "Ciclovir".Instruction( application), reviews of people and doctors say that this drug is highly effective. Ointment goes on sale for 5 g in tubes, sealed in boxes of cardboard.

Pharmacodynamics of the drug

How does the ointment and tablets "Ciclovir" work? Instruction for use informs that this medication is a synthetic antiviral drug. Due to the interaction of its active substance with the enzymes of cells that are infected with the virus, the stopping of their replication is triggered.

By its nature, the drug in question has a structural similarity( chemical) with deoxyguanidine. Therefore, it easily interacts with the synthesis of DNA viruses and selectively exerts a detrimental effect on them.

According to the attached instructions, this medication is particularly active against such viruses as chickenpox, cytomegalovirus, Epstein-Barr virus and herpes simplex.

Pharmacokinetics

Is the drug "Ciclovir"( tablets) absorbed? Instruction for use informs that the process of absorption of this drug occurs partly from the intestine. The biological availability of the medicinal product is 20%.Its highest concentration in the blood is observed 1-2 hours after ingestion.

When entering the systemic circulation, the active substance of the drug binds to proteins by 12-15%.

It should be noted that this medication can easily penetrate the BBB.

Indications for use

When is the drug "Ciclovir"( tablets) prescribed? The instructions for use indicate that this medication is for systemic use in the following cases:

• in the treatment of an infection that was caused by the herpes simplex virus, as well as chicken pox;
• for the prevention of infections that were triggered by the herpes simplex virus and chickenpox( especially in people with a decreased immune status);
• as part of complex treatment for severe immunodeficiency( including HIV infection), as well as for people who underwent bone marrow transplantation;
• for the prevention of cytomegalovirus infection in patients.

As for the local form of the drug, it is actively used in ophthalmic practice( including keratitis and other eye injuries that were caused by the herpes simplex virus).

External use of the drug is indicated for infections of the skin that have been caused by herpes simplex virus and varicella zoster.

Contraindications

What conditions of the patient forbid prescribing the drug "Ciclovir"( tablets)?Instruction for use reports such contraindications:

• breastfeeding;
• hypersensitivity reaction to the main and additional components of the drug;
• children under two years;
• pregnancy period.

The drug "Ciclovir": instruction for the use of

"Ciclovir", which is reviewed at the end of the article, is a very effective antiviral drug. Its dosage and methods of use should be determined only by the doctor. If you do not have the opportunity to visit a doctor, you should carefully read the enclosed instructions.

In what dosage is the preparation "Ciclovir"( tablets) prescribed? Instruction for use informs that this medication should be taken orally. Adult patients and children from two years of age, the drug is prescribed 200-400 mg three or five times a day.

If necessary, the dose of tablets is calculated according to this scheme: 20 mg / kg( that is, up to 800 mg per administration) four times a day.

If a "Cyclovir" is required for a child up to two years, it is prescribed in an amount equal to 1/2 the dose for adult patients.

The duration of treatment with this drug is 5-10 days. In case of renal failure, correction of the dosing regimen is necessary.

How to apply ointment?

As a local and external preparation, "Ciclovir" is prescribed five times a day. The ointment is applied a small layer on the affected area and left in this form for several hours. After a while, the medicine is carefully removed with a cotton pad and repeated application is made.

This form of the drug is advisable to use after herpetic eruptions appear above the skin. Its effectiveness is manifested only when the bubbles begin to burst. As a result of local exposure to the ointment, the infection does not spread to other areas of the skin.

Side effects of

Unfortunately, the administration of the drug in question contributes to the development of many side effects. The use of tablets, even at recommended dosages, may cause nausea, skin rash, vomiting, abdominal pain, diarrhea, headaches, fatigue, dizziness, fever, decreased concentration, drowsiness, hallucinations and insomnia.

Very rarely this medication causes hair loss, a transient increase in the concentration of bilirubin in the blood, creatinine, urea and hepatic enzyme activity, as well as lymphocytopenia, erythropenia and leukopenia.

As for the local use of "Ciclovir", it often causes superficial pinpoint keratitis, a burning sensation at the site of application, as well as conjunctivitis and blepharitis.

With external application of the ointment in the place of application, burning sensations are also possible. In addition, the patient can have a skin rash, peeling, itching, dryness and erythema. If the medication in question accidentally gets on the mucous membranes, then there is a risk of their inflammation.

Cases of overdose

When the dosage of the drug "Ciclovir" is exceeded, the patient may show increased side effects. Such conditions are effectively treated by gastric lavage, hemodialysis, the introduction of plasma and a plasma substitute.

Compatibility with other

agents How does the "Ciclovir" drug interact with other drugs? When this drug is combined with probenecids, the tubular secretion of the active substance decreases. This increases its half-life and concentration in the blood plasma.

Simultaneous reception of "Ciclovir" with nephrotoxic agents increases the risk of developing nephrotoxic effect, especially in people with impaired renal function.

The effect of the drug "Ciclovir" is enhanced with the simultaneous administration of immunostimulants.

Special recommendations

It is undesirable to prescribe the drug in question for those who have severe disorders in the work of the kidneys. When taking "Ciclovir" it is necessary to take into account that it can cause the development of acute renal failure. This is due to the formation of a precipitate in the form of crystals of the active substance.

Treatment of elderly patients should be carried out with sufficient water stress and under the strict supervision of a doctor.

In genital herpes, sexual intercourse should be avoided, since the use of "Ciclovir" does not prevent the transmission of the virus.

Cost and analogues

You can replace "Cyclovir" with such means: "Acyclovir", "Acyclovir-Vishfa", "Acyclovir-Farmak", "Valvir" and so on.

The price of the medication in question is not very high. You can buy this drug in the amount of 10 tablets for 20-30 rubles.

Patient Reviews

Now you know what the "Ciclovir" preparation is. Instructions, testimonials, testimonies are presented in the materials of this article.

Herpetic rashes periodically bother many people. Therefore, tablets and ointments, intended for their treatment, are very popular. Patients argue that the drug "Ciclovir" manifests itself only on the positive side. It helps to quickly eliminate the skin lesions, which were caused by the herpes virus. The only drawback of this medication is the presence of many side effects.