"Fexofast": instructions for use, testimonials and analogues
How should I take the medicine "Fexofast"?Instructions for using this medication will be described below. Also, your attention will be given information about what substances are part of the drug, with what purpose it is prescribed, whether it has contraindications and analogues.
Composition, form and packaging of medicine
Tablets "Fexofast", the instructions of which are in a cardboard pack, contain an active ingredient such as fexofenadine. As for additional components, microcrystalline cellulose, hypromellose, starch, magnesium stearate, povidone, silicon dioxide colloid, lactose and purified water are used as such.
According to the instruction, the agent in question is film coated. Its composition includes such components as propylene glycol, talc, hydroxypropylmethylcellulose, titanium dioxide, isopropyl alcohol, methylene chloride and dye.
You can buy tablets of 180 and 120 mg in blisters and cartons, respectively.
Pharmacological characteristics of the preparation
What features are inherent in the tablets "Fexofast"?Instructions for use indicate that the drug in question is a blocker of H1-histamine receptors. Its active substance is a pharmacologically active metabolite of terfenadine.
The medication has no sedative effect, and also does not cause habituation( after the month of admission).The antihistamine effect of this remedy is manifested after 60 minutes. Its maximum reaches about 6 hours and continues throughout the day.
Specialists have found that with the oral intake of "Fexofast" in an amount of 10-130 mg therapeutic efficacy of the active substance is dose-dependent.
Kinetic features of
How long is the preparation "Fexofast" absorbed? Instructions for use say that after oral administration of tablets, their active substance is absorbed fairly quickly from the intestine.
The highest concentration of active ingredient in the blood is determined after 1-3 hours. After taking the tablet( 180 mg), the average value of the maximum concentration is about 494 ng / ml, and with the application of 120 mg - about 427 ng / ml.
The relationship with plasma proteins varies in the range of 60-70%, and the half-life of the drug after repeated administration is 12-15 hours.
One can not help saying that the medicine in question is excreted together with breast milk. About 5% of the dose is subjected to extrahepatic metabolism( partial).
The drug is mainly taken together with bile( about 80%), and also through the kidneys in unchanged form( about 10%).
Indications for the reception of tablets
What conditions of the patient may require the use of the drug "Fexofast 120"?The instruction informs, that the mentioned medicament possesses a proof antiallergic effect. In this regard, its use is recommended when:
- chronic hives;
- rhinitis is seasonal allergic.
Contraindications to the use of the drug
Do you know what contraindications are available with the "Fexofast" tablets? The instruction says that there are not many prohibitions for this tool. It is not recommended to be taken only under the following conditions:
- hypersensitivity to primary and secondary components;
- baby toddler;
- in childhood( that is, up to 12 years).
Special care should be taken when treating people with chronic renal failure and other disorders in the work of the kidneys and liver.
Medication "Fexofast": instruction on the intake of tablets
How should I take an antiallergic "Fexofast"?The drug in tablets is intended for oral administration with seasonal allergic rhinitis in adults and adolescents from 12 years of age.
The dosage of this remedy should be determined only by a narrow specialist based on the analysis and medical examination. As a rule, with the mentioned disease, the patient is prescribed a drug in the amount of 120 mg once a day.
In such a pathological condition as chronic urticaria, adolescents and adults are prescribed 180 mg of medication once a day.
Duration of treatment is determined on an individual basis, depending on the severity of allergic manifestations and the patient's condition.
Can the side effects of Fexofast 180 tablets cause side effects? The instruction informs, that the given preparation seldom promotes development of undesirable effects. Sometimes patients complain of headaches, nausea, drowsiness and dizziness.
It should also be noted that in rare cases the medication in question can cause a feeling of fatigue, insomnia and other sleep problems, nervousness, as well as hives, skin rashes, itching and other reactions of intolerance.
Symptoms of an overdose of
Before taking the "Fexofast 180" tablets, the instruction must be studied by the patient. It indicates the recommended and effective dosages of this product, as well as the frequency of its administration.
If the indicated amount of the drug is exceeded, the patient may experience symptoms of an overdose such as dizziness, dryness in the mouth and drowsiness.
To eliminate such conditions, standard measures are taken to eliminate unabsorbed medication from the gastrointestinal tract. Symptomatic and supportive therapy is also provided.
Compatibility with other medications
The drug "Fexofast" is not subjected to biological transformation in the liver. In this regard, it does not interact with other medications that are exposed to hepatic metabolism.
It has been proved by specialists that when combined with "Ketoconazole" and "Erythromycin", the concentration of fexofenadine in the blood increases 3 times. This is due to increased absorption of the drug from the gastrointestinal tract, as well as a reduction in the excretion of bile and gastrointestinal secretion.
At simultaneous reception of aluminum and magnesium-containing antacids for ¼ hours before the reception of "Fexofast", a decrease in its bioavailability is observed. The interval between taking these medications should be 120 minutes.
It should be noted that the tablets "Fexofast" does not interact with "Omeprazol" and drugs that are metabolized in the liver.
Drug analogues and its price
How much are Fexofast 120 tablets worth? Instructions for use do not answer the question posed. You can learn it only in the pharmacy. You can buy this medication for 170-230 rubles. As for similar drugs, they include such drugs: Telfadine, Allegra, Fexofenadine, Allerfex, Fexadin, Gifast, Telfast.
Now you have an idea of how to use the medication "Fexofast".The instructions for taking this medication have been described above.
Unfortunately, allergic reactions disturb many people. To get rid of their manifestations, patients are often prescribed "Fexofast" tablets.
Most people leave only positive reviews about this medicine. They say that this is a highly effective drug that helps to eliminate all allergic manifestations.
However, there are also patients who claim that the drug in question only gives temporary relief.