Desloratadine: instructions for use, reviews, analogues

Allergic reactions occur in humans only with a hypersensitive immune system. As a rule, they are manifested with repeated exposure to the allergen on the body, previously sensitized to them. Such conditions quite often prevent a person from leading a normal life.

To help patients with hypersensitive immunity, pharmaceutical companies began to produce special anti-allergic drugs that significantly improve the quality of life and the condition of the patient.

The most popular means to combat allergic manifestations is the drug Desloratadine. Instructions for use, analogs, form of production and indications of this medication will be provided below.

Description, packaging, form and composition of

Medication "Desloratadine", the instruction for use of which is placed in a pack of cardboard, is issued in the form of blue tablets of round and biconcave form. They are film-coated and have a white core( on the cross-section).

Active ingredient of this drug is desloratadine. In addition to it, the tablets also contain additional elements in the form of corn starch, calcium hydrophosphate dihydrate, microcrystalline cellulose, magnesium stearate and talc.

As for the film sheath, it is made from a dry mixture consisting of polyvinyl alcohol, titanium dioxide, talc, macragol 3350, an aluminum dye based on a dye and a yellow iron oxide.

You can buy this medication in carton packs and boxes, respectively.

Pharmacodynamics of the preparation

What is an antiallergic agent such as Desloratadine( tablets)?Instructions for use indicate that it is a blocker of H1-histamine receptors, which has a prolonged effect.

This medication is an active metabolite of Loratadine. By its strength of action, it surpasses it 2-4 times.

This drug contributes to the inhibition of a number of allergic inflammation reactions( releases cytokines, chemokines, interleukins and prostaglandin D2).

Antiallergic tablets "Desloratadine" have anti-edematous and antipruritic effect, facilitate the course of allergies, reduce the hyperreactivity of bronchi and the severity of allergen-dependent bronchospasm, and also eliminate spasms of smooth muscles. The effect of a medication taken orally is observed within a day.

It should also be noted that this drug has no effect on the central nervous system, including a dosage of 7.5 mg. He does not have cardiotoxic effects, effects on the rate of psychomotor reactions and sedation.

Kinetic features of

Where is the absorption of the drug Desloratadine? Instructions for use indicate that the absorption of this drug is carried out from the digestive tract.

The lowest concentration of the drug is found in the blood after 35 minutes, and the largest - in 3 hours.

The active substance of the drug is 87% bound to plasma proteins. Taking a dosage of 20 mg for two weeks does not contribute to the appearance of signs of cumulation.

The use of food does not affect the distribution of the drug in the human body.

This agent is metabolized intensively. It is excreted together by calves and urine. The half-life of the drug is 20-35 hours.

Indications for use

In what manifestations of an allergic reaction is it necessary to prescribe the drug Desloratadine Teva? Instructions for use indicate the following indications:

• chronic urticaria;
• is hilarious;
• allergic rhinitis year-round.

Contraindications of tablets

When is it forbidden to use tablets "Desloratadine"?Instructions for use( for children this medication is prescribed only after reaching the age of 12) reports the following contraindications to the medicinal product:

• gestation period;
• hypersensitivity to the ingredients of the medication;
• time of breastfeeding;
• lactose intolerance;
• disorders of absorption of glucose-galactose.

Medication Desloratadine: instructions for use

How should I take this remedy? According to specialists, this drug requires oral administration at the same time.

The use of tablets is not dependent on eating. Antiallergic tablet should be swallowed in its entirety.

Adolescents over 12 years of age, as well as adults, are prescribed medication at a dosage of 5 mg once daily.

As for the synonym "Desloratadine Teva", it is used in the same quantity and with the same multiplicity.

The duration of treatment with this drug depends on the frequency of allergy signs and the course of the disease.

As is known, with intermittent rhinitis, symptoms can be observed for less than four weeks per year. Therapy of such a disease should be completed only after the disappearance of all its signs. Renewal of the drug is desirable when they occur again.

As for persistent rhinitis, the symptoms of such an allergy may be noted more often than 4 weeks per year. As a rule, the appearance of such reactions is associated with a constant contact with the allergen. In such cases, treatment should continue until the contact with the allergen is complete.

Side effects of

What are the undesirable reactions that occur when taking desloratadine tablets? Instructions for use, consumer reviews indicate the following side effects:

• angioedema, headache, anaphylaxis, hallucinations, dyspnea, convulsions, itching, dizziness, rash, insomnia, urticaria;
• drowsiness, tachycardia, psychomotor hyperactivity, palpitation;
• dry mouth, myalgia, abdominal pain, fatigue, nausea, pharyngitis, vomiting, dysmenorrhea, dyspepsia;
• increased activity of liver enzymes, diarrhea, increased bilirubin concentration, hepatitis.

Cases of an overdose of

What happens with increased intake of doses of Desloratadine Teva? The instruction says that the daily use of tablets in the amount of 20 mg for two weeks does not cause any changes on the part of the CCC.

It should also be noted that taking a medication at a dosage of 45 mg for 10 days does not contribute to the prolongation of the QT interval and the occurrence of any significant side effects.

Similar remedies and cost of

If there are contraindications to taking Desloratadine tablets, they can be replaced with such means as AlerigoMax, Erius, Elisei, Nalorius, Lordestin, Ezlor, Dezal,"Eridez".The method of application of such preparations can differ from the method of taking Desloratadine. Therefore, only experienced allergist

should prescribe them. You can buy the medication for 200-320 rubles( 10 tablets).

Reviews about the antiallergic agent

Now you know what the "Desloratadine" medication is needed for. Instructions for use of this medication were presented above.

This drug belongs to the most modern and popular antihistamines.

Patients claim that it is very effective in the treatment of allergic diseases. Receiving the pill quickly eliminates nasal congestion.

Also considered medication is often used in the combination of rhinitis with bronchial asthma( atopic).

In people with chronic urticaria, it quickly enough to stop all the symptoms of the disease.

Another advantage of this drug is that it does not have a sedative effect and a negative effect on the heart.