"Bronhobos"( syrup): instructions for use, reviews, analogs, prices

In what dose is the drug "Bronhobos"( syrup) prescribed? Instructions for the use of a mucolytic drug are described in detail below. Also in the materials of this article you can find information about the purposes for which the medicine is used, how much it costs, whether it has side reactions, analogues and contraindications.

Composition and packaging

In which packaging is Bronchobos( syrup) sold? Instructions for the use of mucolytic agents are enclosed in a pack of cardboard, where a measuring spoon of polystyrene with labels is located, as well as a bottle of dark brown glass with an aluminum cover that has a sealant, a protective mechanism and a first opening control.

Carbocysteine ​​is the active substance of this drug. It also contains auxiliary compounds in the form of ethanol, glycerol, sodium hydroxide, citric acid monohydrate, carmellose sodium, methylparahydroxybenzoate, propylparahydroxybenzoate, sodium saccharinate, azorubin, raspberry and purified water.

The "Bronhobos" syrup, described below, is a 2.5% or 5% transparent preparation with a slightly viscous consistency, a raspberry flavor and a bright red color.

Pharmacodynamics of the drug

Mucolytic drugs, including the syrup "Bronhobos", have an expectorant effect. This effect of the drug is due to the activation of the enzyme - sialic transferase, which is produced in cells of a cup-shaped form in bronchial mucosa.

The drug normalizes the numerical ratio of acidic, as well as neutral sialomucins in bronchial secretion. In addition, it restores the viscosity of mucus and its elasticity.

What other features do mucolytic drugs have? They contribute to the regeneration of the mucous membranes, normalize the structure, and also activate the work of the ciliary epithelium. The "Bronhobos" syrup restores the secretion of immunoglobulin A as a specific defense, as well as the number of sulfhydryl groups in mucus and its components as a nonspecific defense. Also this drug improves mucociliary clearance.

Pharmacokinetic parameters of the drug

The drug "Bronhobos", the price of which will be indicated below, is absorbed quickly and completely. However, it has a rather low bioavailability( less than 10% of the dose taken).The highest level of active carbocisteine ​​in the mucous membranes and blood is reached after a lapse of 1.5-2 hours. Its therapeutic level persists for 8 hours. The longest drug is delayed in the liver, blood flow and middle ear. At maximum concentrations, it accumulates in the secretion of the bronchi( about 17.5% of the dose taken).

The drug is metabolized in the liver. It is characterized by the effect of the first passage. About 60-90% of the medication is excreted by the kidneys in unmodified form.

The half-life of the drug is 2-3 hours. Its complete excretion takes place after three days.

Indications for the use of the syrup

What is the purpose of Bronhobos for children and adults? According to the instructions, this syrup effectively helps with:

• inflammatory processes occurring in the paranasal sinus and middle ear, including sinusitis, rhinitis and otitis media;
• chronic and acute bronchopulmonary diseases, accompanied by a violation of mucus excretion and secretion( eg, bronchitis, tracheitis, bronchial asthma, tracheobronchitis and bronchiectasis).

In addition to the above, the medicament in question is actively used during the preparation of the patient for bronchography or bronchoscopy.

Contraindications to the use of

When is it not recommended to take Bronhobos( syrup)?Instructions for use indicate the following contraindications for all dosage forms:

• ulcer of the duodenum and stomach( especially with exacerbation);
• Hypersensitivity to the components of the drug;
• cystitis and chronic glomerulonephritis( including with exacerbation);
• age is up to 15 years.

For 2.5% and 5% syrup:

• epilepsy;
• various liver diseases, alcoholism;
• disease of the brain and trauma of this organ;
• breastfeeding and pregnancy.

For 2.5% syrup:

• age is up to 3 years.

Conditions for the cautious use of the drug:

• the presence of an ulcer of the duodenum and stomach in an anamnesis.

Preparation: Bronhobos( syrup): instruction for use

According to the attached instructions, this medication must be taken orally. The dosage of the drug should be determined using a measuring spoon.

For adults, the drug is prescribed in an amount of 15 ml, which is 3 scoops of a 5% syrup( three times a day).

Babies at the age of 3-6 years 2.5% medicament give 5 ml 2-4 times a day, that is, in the amount of 1 measuring spoon for one reception.

For children from 6 years, prescribe 5-10 ml of 2.5% syrup three times a day, that is, 1-2 scoops.

Drug overdose

The patient may experience stomach pain, diarrhea, and nausea when taking higher doses of syrup. To eliminate such deviations prescribe symptomatic treatment.

Adverse events

Taking medication Bronhobos can cause undesirable effects on the part of the following organs and systems:

• GI tract: epigastric pain, nausea, bleeding, vomiting, diarrhea.
• Immune system: allergic reactions in the form of exanthema, urticaria, skin itch, angioedema.
• Other: dizziness, weakness, malaise.
• People with bronchial asthma and elderly patients may have airway obstruction.

Drug interaction

When taking any medicinal forms of the drug:

• The bronchodilator effect of the drug "Theophylline" is increased.
• In the treatment of infectious and inflammatory processes in the lower and upper respiratory tract, there may be a mutual increase in glucocorticoid efficacy, as well as a separate antibacterial effect.
• With atropine-like drugs, the antitussive effect is weakened.

When taking the syrup:

• With extreme caution( because of the presence of ethanol) is used with drugs that cause fever, vomiting, redness and tachycardia.
• With extreme caution( because of the presence of ethanol) is taken with such drugs as "Cefamandol", "Disulfiram", "Cefoperazone", "Latamoxef", "Chloramphenicol", "Glipizide", "Glibenclamide", "Chlorpropamide", "Tolbutamid, Griseofulvin, Metronidazole, Tinidazol, Sequinazole, Ornidazole, Procarbazine, and Ketoconazole.

Special recommendations

Syrup "Bronhobos" contains ethanol. In connection with this, he is cautiously prescribed to children and people suffering from alcoholism. After taking the drug, patients notice impaired attention and speed of psychomotor reactions. In this regard, use this medication is not recommended for drivers of vehicles and those who work with complex mechanisms.

Terms of Sale, Storage and Shelf Life

This drug is sold in pharmacies without a doctor's prescription. Keep it in a place inaccessible to children, observing a temperature regime of 16-30 degrees. The shelf life of the syrup is three years( without compromising the integrity of the package).

Preparation "Bronhobos": Analogues and Cost

Currently, there are many analogues of the drug under consideration. The closest to the mechanism of action is the drug "Fluviert"( syrup).He is also a good mucolytic. In addition, the presented medication can be replaced by such means as "Fljuditik", "Bronkatar", "Libexin Muko", "Mukopron" and "Mukosol".

How much does Bronhobos cost? The price of this medicine depends on its form of release.5% syrup can be purchased for 550-570 rubles, and 2.5% of the drug - for 420 rubles.

Reviews about the drug

As well as the preparation "Fluviert", the syrup "Bronhobos" is a quality and effective mucolytic. This opinion is shared by the majority of patients who used this medication for the treatment of chronic and acute bronchopulmonary diseases.

According to the opinion of experienced specialists, this preparation is able to quickly and efficiently dilute, as well as excrete sputum from the bronchi. Another plus of this tool is that it can be given to young children from two years old, as evidenced by many reviews. This is due to the fact that the syrup in question has virtually no side effects and contraindications.

As for negative reviews, they are most often associated with the price of a mucolytic drug. However, pharmacists claim that the cost of this drug is fully justified, since it is one of the most effective medicines against bronchopulmonary diseases.