Clomifen: reviews."Klomifen": instructions for use, description, price

"Clomiphene citrate" is a synthetic non-steroidal drug characterized in pharmacology as an antiestrogen. It is widely used for medical purposes as a stimulator of ovulation in women, and in bodybuilding as a means for building muscle mass.

The effect of Clomifene is based on its partial structural similarity to estrogen produced in the human body. Due to this, the main substance of the described agent can bind to the hormone receptors of estrogen, which stimulates the increase in the production of gonadotropins of FSH and LH.And this, in turn, increases the secretion of testosterone in men and estrogen in women.

Further in the article, we will describe in more detail the effect of the drug Klomifen in various cases of its use.

As a drug used in medicine

This drug is prescribed for men with androgen deficiency, with oligospermia and delay in sexual and physical development in adolescents.

The drug "Clomiphene citrate" is popular in gynecology as a tool that can help a woman with diagnosed ovarian dysfunction, ranging from minor deviations to serious pathologies.

For women, this drug is indicated for uterine bleeding, postcontraceptive amenorrhea, galactorrhea that has arisen against the background of the tumor, as well as with polycystic ovaries - the result will not be long in coming. The main thing at the same time is precisely to establish the causes of the pathological condition and to form an adequate therapeutic course.

As Clomifene is a tablet with a strong effect, long-term use is not advisable. And to prevent this, the doctor must determine the exact time to start the course. For this, for example, a woman with anovulatory infertility is offered to undergo an ovulation test( usually from the twelfth to the fifteenth day with a 28-day cycle or from the eleventh to the twentieth - with an irregular one) that helps to specify the dates of the first and last day of treatment.

How ovulation induction is performed with Clomiphen: Instruction

Induction of ovulation( stimulation of the process of egg maturation with the help of special medicines) is usually shown to patients with rare menstruation, to those who do not have it, and to whose cause of infertilitycan not figure out. All of them are usually prescribed the most effective drug for such cases, according to experts, which is Clomiphene.

Testimonials of medical practitioners confirm that it should be taken for five days at the very beginning of the cycle( the standard dose is 50 mg per day at bedtime, regardless of food intake).The course of the induction process should be monitored by a specialist, checking its results with ultrasound, baseline temperature measurements and determining the amount of estrogen in the blood.

As a rule, as a result of the drug, ovulation occurs 5 days after the last dose of the drug, but in some patients it can take from 18 to 23 days. In such cases, the development of follicles is monitored by ultrasound.

By the way, taking Clomifene increases the likelihood of multiple pregnancy.

Side effects that prevent pregnancy, with the use of the drug

Despite the relative safety of the described drug, the Klamifen reviews of the specialists emphasize its ability to provoke the inferiority of mucus secreted in the cervix. And this, in turn, can be a barrier to sperm, as a result of which even with good ovulation a woman has problems with conception. To avoid this problem, doctors recommend that patients in the first half of the cycle perform postcoital testing after each induction of Clomiphen.

Another negative consequence of using the described agent is the possibility of reducing the quality of the endometrium. This is manifested in the fact that it is thinned, why successful implantation of the fetal egg becomes practically impossible.

In addition to the listed side effects, some experts note still complaints of patients for hot flashes, visual impairment, vaginal dryness, and also a manifestation of ovarian hyperstimulation syndrome. In some women, the growth of cysts in the ovary can also be observed, which makes it necessary to conduct an ultrasound before the induction course.

Contraindications to the use of

It should be mentioned that this agent is taken orally, while it is well absorbed and metabolized by the liver. The half-life period, as a rule, is from 5 to 7 days.

The Clomifen reviews available warn of contraindications to its use. It can not be administered:

• to pregnant women,
• to patients with severe hepatic or renal dysfunction,
• with uterine bleeding of unclear etiology,
• ovarian cyst,
• susceptibility to thrombosis,
• for tumors or pituitary hypofunction,
• , and in the presence of malignant andbenign neoplasm.

All these diseases serve as a serious obstacle to the prescription of the drug, so they should be reported to the treating doctor in a timely manner.

Use of Clomiphen in bodybuilding

As mentioned above, the described agent is used not only for medical purposes: both novice athletes and professionals actively use the drug Klomifen. Its use in sports is explained by excellent indicators in the buildup of muscle mass and the fact that unlike many similar drugs, it does not reduce the concentration of natural testosterone in the blood, but, on the contrary, leads to its increased production.

In addition, experts suggest that men take the drug and with the occurrence in some cases after the course of steroids of gynecomastia( an increase in men in the breast).By the way, the anti-estrogen "Klomifen" to some extent has anabolic properties, although not as powerful as in steroid preparations.

Preparation "Clomifen": instruction for use in bodybuilding

In heavy sports and bodybuilding, Clomifene is taken, as a rule, regardless of the weight or other indices of the athlete. Its dosage usually ranges from 50 to 150 mg per day at a time. According to experts, a greater amount of the drug is inappropriate, because even its minimum dose( 50 mg) can significantly affect the increase in testosterone and muscle growth.

The course of reception of the described means lasts no more than three weeks. And, as evidenced by the reviews, this period is enough to make the effect of its application obvious.

Comments on the admission of the drug "Clomifen"

About the drug "Clomifene" reviews to find it is not difficult, because it enjoys an enviable popularity among doctors and gynecologists, and athletes-athletes.

However, among the many laudatory reviews there are also negative statements. But they are based, as practice shows, on the wrong and uncontrolled admission of the said remedy, which, naturally, entails negative consequences. As a rule, they include nausea, vomiting, headache, uncomfortable and painful sensations in the area of ​​the mammary glands, as well as an increase in temperature.

Patients' complaints about mood swings and insomnia associated with taking Klomiphen tablets are also frequent.

But experts confirm once again that in most cases all these phenomena are caused by improper selection of the dosage of the drug and disappear soon after it is discontinued.

A little more about the tablets "Clomifen"

To avoid fakes of this very popular drug, it is best to purchase the drug "Klomifen" in the pharmacy. It is available in the form of round white tablets, placed in a contour package of ten pieces or in a plastic jar.

One tablet contains 0.05 g of clomiphene citrate, as well as auxiliaries in the form of lactose, potato starch, food gelatin, magnesium stearate and talc.

Special remarks about the drug "Clomifen"

Judging by the opinions of specialists and consumers, regardless of whether it was people taking it as a medicine or athletes who want to increase the amount of muscle, the described drug is excellent in helping to cope with problems. And that's why, despite the fact that the price of Klomiphen tablets is quite high( up to 3000 rubles), the demand for them does not decrease.

But I want to remind once again: this drug, as well as other medications, in no case can be assigned to yourself and take without consulting a specialist. You can cause irreparable harm to your health! Be careful and prudent!